Daily Papers

Federated learning alleviates the privacy risk in distributed learning by transmitting only the local model updates to the central server. However, it faces challenges including statistical heterogeneity of clients' datasets and resource constraints of client devices, which severely impact the training performance and user experience. Prior works have tackled these challenges by combining personalization with model compression schemes including quantization and pruning. However, the pruning is data-dependent and thus must be done on the client side which requires considerable computation cost. Moreover, the pruning normally trains a binary supermask in {0, 1} which significantly limits the model capacity yet with no computation benefit. Consequently, the training requires high computation cost and a long time to converge while the model performance does not pay off. In this work, we propose HideNseek which employs one-shot data-agnostic pruning at initialization to get a subnetwork based on weights' synaptic saliency. Each client then optimizes a sign supermask in {-1, +1} multiplied by the unpruned weights to allow faster convergence with the same compression rates as state-of-the-art. Empirical results from three datasets demonstrate that compared to state-of-the-art, HideNseek improves inferences accuracies by up to 40.6\% while reducing the communication cost and training time by up to 39.7\% and 46.8\% respectively.

The prediction of saliency areas in images has been traditionally addressed with hand crafted features based on neuroscience principles. This paper however addresses the problem with a completely data-driven approach by training a convolutional network. The learning process is formulated as a minimization of a loss function that measures the Euclidean distance of the predicted saliency map with the provided ground truth. The recent publication of large datasets of saliency prediction has provided enough data to train a not very deep architecture which is both fast and accurate. The convolutional network in this paper, named JuntingNet, won the LSUN 2015 challenge on saliency prediction with a superior performance in all considered metrics.

Recent progress in brain-guided image generation has improved the quality of fMRI-based reconstructions; however, fundamental challenges remain in preserving object-level structure and semantic fidelity. Many existing approaches overlook the spatial arrangement of salient objects, leading to conceptually inconsistent outputs. We propose a saliency-driven decoding framework that employs graph-informed saliency priors to translate structural cues from brain signals into spatial masks. These masks, together with semantic information extracted from embeddings, condition a diffusion model to guide image regeneration, helping preserve object conformity while maintaining natural scene composition. In contrast to pipelines that invoke multiple diffusion stages, our approach relies on a single frozen model, offering a more lightweight yet effective design. Experiments show that this strategy improves both conceptual alignment and structural similarity to the original stimuli, while also introducing a new direction for efficient, interpretable, and structurally grounded brain decoding.

Vision-language models are increasingly deployed in high-stakes settings, yet their susceptibility to sycophantic manipulation remains poorly understood, particularly in relation to how these models represent visual information internally. Whether models whose visual representations more closely mirror human neural processing are also more resistant to adversarial pressure is an open question with implications for both neuroscience and AI safety. We investigate this question by evaluating 12 open-weight vision-language models spanning 6 architecture families and a 40times parameter range (256M--10B) along two axes: brain alignment, measured by predicting fMRI responses from the Natural Scenes Dataset across 8 human subjects and 6 visual cortex regions of interest, and sycophancy, measured through 76,800 two-turn gaslighting prompts spanning 5 categories and 10 difficulty levels. Region-of-interest analysis reveals that alignment specifically in early visual cortex (V1--V3) is a reliable negative predictor of sycophancy (r = -0.441, BCa 95\% CI [-0.740, -0.031]), with all 12 leave-one-out correlations negative and the strongest effect for existence denial attacks (r = -0.597, p = 0.040). This anatomically specific relationship is absent in higher-order category-selective regions, suggesting that faithful low-level visual encoding provides a measurable anchor against adversarial linguistic override in vision-language models. We release our code on https://github.com/aryashah2k/Gaslight-Gatekeep-Sycophantic-Manipulation{GitHub} and dataset on https://huggingface.co/datasets/aryashah00/Gaslight-Gatekeep-V1-V3{Hugging Face}

The spectral behaviour of the synaptic matrix, representing the neuronal connection strengths, is an important tool to analyze the stability and transient dynamics of a typical brain as well as its learning process and memory capacity. The complexity of the brain due to large number of neurons as well as underlying transient mechanisms e.g. homeostasis, seizure or synaptic plasticity can lead to networks with time-varying degree and type of sparsity. This renders an exact determination of the synaptic matrix not only technically difficult but also meaningless, leaving its statistical analysis as the best available theoretical approach. This motivates us to pursue a spectral analysis of the synaptic matrix models with different type of sparsity and thereby analyze latter's role on various aspects of network dynamics and stability. Our results have potential relevance for detemining the type of synaptic sparsity required to induce a specific brain function or desired transient mechanism e.g for pharmacological effects or physiological modulators.

Vital to primary visual processing, retinal circuitry shows many similar structures across a very broad array of species, both vertebrate and non-vertebrate, especially functional components such as lateral inhibition. This surprisingly conservative pattern raises a question of how evolution leads to it, and whether there is any alternative that can also prompt helpful preprocessing. Here we design a method using genetic algorithm that, with many degrees of freedom, leads to architectures whose functions are similar to biological retina, as well as effective alternatives that are different in structures and functions. We compare this model to natural evolution and discuss how our framework can come into goal-driven search and sustainable enhancement of neural network models in machine learning.

We propose a formal mathematical model for sparse representations and active dendrites in neocortex. Our model is inspired by recent experimental findings on active dendritic processing and NMDA spikes in pyramidal neurons. These experimental and modeling studies suggest that the basic unit of pattern memory in the neocortex is instantiated by small clusters of synapses operated on by localized non-linear dendritic processes. We derive a number of scaling laws that characterize the accuracy of such dendrites in detecting activation patterns in a neuronal population under adverse conditions. We introduce the union property which shows that synapses for multiple patterns can be randomly mixed together within a segment and still lead to highly accurate recognition. We describe simulation results that provide further insight into sparse representations as well as two primary results. First we show that pattern recognition by a neuron with active dendrites can be extremely accurate and robust with high dimensional sparse inputs even when using a tiny number of synapses to recognize large patterns. Second, equations representing recognition accuracy of a dendrite predict optimal NMDA spiking thresholds under a generous set of assumptions. The prediction tightly matches NMDA spiking thresholds measured in the literature. Our model matches many of the known properties of pyramidal neurons. As such the theory provides a mathematical framework for understanding the benefits and limits of sparse representations in cortical networks.

From a falcon detecting prey to humans recognizing faces, many species exhibit extraordinary abilities in rapid visual localization and classification. These are made possible by a specialized retinal region called the fovea, which provides high acuity at the center of vision while maintaining lower resolution in the periphery. This distinctive spatial organization, preserved along the early visual pathway through retinotopic mapping, is fundamental to biological vision, yet remains largely unexplored in machine learning. Our study investigates how incorporating foveated retinotopy may benefit deep convolutional neural networks (CNNs) in image classification tasks. By implementing a foveated retinotopic transformation in the input layer of standard ResNet models and re-training them, we maintain comparable classification accuracy while enhancing the network's robustness to scale and rotational perturbations. Although this architectural modification introduces increased sensitivity to fixation point shifts, we demonstrate how this apparent limitation becomes advantageous: variations in classification probabilities across different gaze positions serve as effective indicators for object localization. Our findings suggest that foveated retinotopic mapping encodes implicit knowledge about visual object geometry, offering an efficient solution to the visual search problem - a capability crucial for many living species.

Attention Model has now become an important concept in neural networks that has been researched within diverse application domains. This survey provides a structured and comprehensive overview of the developments in modeling attention. In particular, we propose a taxonomy which groups existing techniques into coherent categories. We review salient neural architectures in which attention has been incorporated, and discuss applications in which modeling attention has shown a significant impact. We also describe how attention has been used to improve the interpretability of neural networks. Finally, we discuss some future research directions in attention. We hope this survey will provide a succinct introduction to attention models and guide practitioners while developing approaches for their applications.

Redundancies and correlations in the responses of sensory neurons seem to waste neural resources but can carry cues about structured stimuli and may help the brain to correct for response errors. To assess how the retina negotiates this tradeoff, we measured simultaneous responses from populations of ganglion cells presented with natural and artificial stimuli that varied greatly in correlation structure. We found that pairwise correlations in the retinal output remained similar across stimuli with widely different spatio-temporal correlations including white noise and natural movies. Meanwhile, purely spatial correlations tended to increase correlations in the retinal response. Responding to more correlated stimuli, ganglion cells had faster temporal kernels and tended to have stronger surrounds. These properties of individual cells, along with gain changes that opposed changes in effective contrast at the ganglion cell input, largely explained the similarity of pairwise correlations across stimuli where receptive field measurements were possible.

Large Vision Language Models (LVLMs) have demonstrated remarkable capabilities in understanding and describing visual content, achieving state-of-the-art performance across various vision-language tasks. However, these models frequently exhibit hallucination behavior, where they generate descriptions containing objects or details absent in the input image. Our work investigates this phenomenon by analyzing attention patterns across transformer layers and heads, revealing that hallucinations often stem from progressive degradation of visual grounding in deeper layers. We propose a novel attention modification approach that combines selective token emphasis and head-specific modulation to maintain visual grounding throughout the generation process. Our method introduces two key components: (1) a dual-stream token selection mechanism that identifies and prioritizes both locally informative and spatially significant visual tokens, and (2) an attention head-specific modulation strategy that differentially amplifies visual information processing based on measured visual sensitivity of individual attention heads. Through extensive experimentation on the MSCOCO dataset, we demonstrate that our approach reduces hallucination rates by up to 62.3\% compared to baseline models while maintaining comparable task performance. Our analysis reveals that selectively modulating tokens across attention heads with varying levels of visual sensitivity can significantly improve visual grounding without requiring model retraining.

Saliency methods seek to explain the predictions of a model by producing an importance map across each input sample. A popular class of such methods is based on backpropagating a signal and analyzing the resulting gradient. Despite much research on such methods, relatively little work has been done to clarify the differences between such methods as well as the desiderata of these techniques. Thus, there is a need for rigorously understanding the relationships between different methods as well as their failure modes. In this work, we conduct a thorough analysis of backpropagation-based saliency methods and propose a single framework under which several such methods can be unified. As a result of our study, we make three additional contributions. First, we use our framework to propose NormGrad, a novel saliency method based on the spatial contribution of gradients of convolutional weights. Second, we combine saliency maps at different layers to test the ability of saliency methods to extract complementary information at different network levels (e.g.~trading off spatial resolution and distinctiveness) and we explain why some methods fail at specific layers (e.g., Grad-CAM anywhere besides the last convolutional layer). Third, we introduce a class-sensitivity metric and a meta-learning inspired paradigm applicable to any saliency method for improving sensitivity to the output class being explained.

Understanding of human visual perception has historically inspired the design of computer vision architectures. As an example, perception occurs at different scales both spatially and temporally, suggesting that the extraction of salient visual information may be made more effective by paying attention to specific features at varying scales. Visual changes in the body due to physiological processes also occur at different scales and with modality-specific characteristic properties. Inspired by this, we present BigSmall, an efficient architecture for physiological and behavioral measurement. We present the first joint camera-based facial action, cardiac, and pulmonary measurement model. We propose a multi-branch network with wrapping temporal shift modules that yields both accuracy and efficiency gains. We observe that fusing low-level features leads to suboptimal performance, but that fusing high level features enables efficiency gains with negligible loss in accuracy. Experimental results demonstrate that BigSmall significantly reduces the computational costs. Furthermore, compared to existing task-specific models, BigSmall achieves comparable or better results on multiple physiological measurement tasks simultaneously with a unified model.

The precise timing of spikes emitted by neurons plays a crucial role in shaping the response of efferent biological neurons. This temporal dimension of neural activity holds significant importance in understanding information processing in neurobiology, especially for the performance of neuromorphic hardware, such as event-based cameras. Nonetheless, many artificial neural models disregard this critical temporal dimension of neural activity. In this study, we present a model designed to efficiently detect temporal spiking motifs using a layer of spiking neurons equipped with heterogeneous synaptic delays. Our model capitalizes on the diverse synaptic delays present on the dendritic tree, enabling specific arrangements of temporally precise synaptic inputs to synchronize upon reaching the basal dendritic tree. We formalize this process as a time-invariant logistic regression, which can be trained using labeled data. To demonstrate its practical efficacy, we apply the model to naturalistic videos transformed into event streams, simulating the output of the biological retina or event-based cameras. To evaluate the robustness of the model in detecting visual motion, we conduct experiments by selectively pruning weights and demonstrate that the model remains efficient even under significantly reduced workloads. In conclusion, by providing a comprehensive, event-driven computational building block, the incorporation of heterogeneous delays has the potential to greatly improve the performance of future spiking neural network algorithms, particularly in the context of neuromorphic chips.

Learning synaptic weights of spiking neural network (SNN) models that can reproduce target spike trains from provided neural firing data is a central problem in computational neuroscience and spike-based computing. The discovery of the optimal weight values can be posed as a supervised learning task wherein the weights of the model network are chosen to maximize the similarity between the target spike trains and the model outputs. It is still largely unknown whether optimizing spike train similarity of highly recurrent SNNs produces weight matrices similar to those of the ground truth model. To this end, we propose flexible heuristic supervised learning rules, termed Pre-Synaptic Pool Modification (PSPM), that rely on stochastic weight updates in order to produce spikes within a short window of the desired times and eliminate spikes outside of this window. PSPM improves spike train similarity for all-to-all SNNs and makes no assumption about the post-synaptic potential of the neurons or the structure of the network since no gradients are required. We test whether optimizing for spike train similarity entails the discovery of accurate weights and explore the relative contributions of local and homeostatic weight updates. Although PSPM improves similarity between spike trains, the learned weights often differ from the weights of the ground truth model, implying that connectome inference from spike data may require additional constraints on connectivity statistics. We also find that spike train similarity is sensitive to local updates, but other measures of network activity such as avalanche distributions, can be learned through synaptic homeostasis.

In the study of LLMs, sycophancy represents a prevalent hallucination that poses significant challenges to these models. Specifically, LLMs often fail to adhere to original correct responses, instead blindly agreeing with users' opinions, even when those opinions are incorrect or malicious. However, research on sycophancy in visual language models (VLMs) has been scarce. In this work, we extend the exploration of sycophancy from LLMs to VLMs, introducing the MM-SY benchmark to evaluate this phenomenon. We present evaluation results from multiple representative models, addressing the gap in sycophancy research for VLMs. To mitigate sycophancy, we propose a synthetic dataset for training and employ methods based on prompts, supervised fine-tuning, and DPO. Our experiments demonstrate that these methods effectively alleviate sycophancy in VLMs. Additionally, we probe VLMs to assess the semantic impact of sycophancy and analyze the attention distribution of visual tokens. Our findings indicate that the ability to prevent sycophancy is predominantly observed in higher layers of the model. The lack of attention to image knowledge in these higher layers may contribute to sycophancy, and enhancing image attention at high layers proves beneficial in mitigating this issue.

By computing the rank correlation between attention weights and feature-additive explanation methods, previous analyses either invalidate or support the role of attention-based explanations as a faithful and plausible measure of salience. To investigate whether this approach is appropriate, we compare LIME, Integrated Gradients, DeepLIFT, Grad-SHAP, Deep-SHAP, and attention-based explanations, applied to two neural architectures trained on single- and pair-sequence language tasks. In most cases, we find that none of our chosen methods agree. Based on our empirical observations and theoretical objections, we conclude that rank correlation does not measure the quality of feature-additive methods. Practitioners should instead use the numerous and rigorous diagnostic methods proposed by the community.

Recent studies have examined attention dynamics in large vision-language models (LVLMs) to detect hallucinations. However, existing approaches remain limited in reliably distinguishing hallucinated from factually grounded outputs, as they rely solely on forward-pass attention patterns and neglect gradient-based signals that reveal how token influence propagates through the network. To bridge this gap, we introduce LVLMs-Saliency, a gradient-aware diagnostic framework that quantifies the visual grounding strength of each output token by fusing attention weights with their input gradients. Our analysis uncovers a decisive pattern: hallucinations frequently arise when preceding output tokens exhibit low saliency toward the prediction of the next token, signaling a breakdown in contextual memory retention. Leveraging this insight, we propose a dual-mechanism inference-time framework to mitigate hallucinations: (1) Saliency-Guided Rejection Sampling (SGRS), which dynamically filters candidate tokens during autoregressive decoding by rejecting those whose saliency falls below a context-adaptive threshold, thereby preventing coherence-breaking tokens from entering the output sequence; and (2) Local Coherence Reinforcement (LocoRE), a lightweight, plug-and-play module that strengthens attention from the current token to its most recent predecessors, actively counteracting the contextual forgetting behavior identified by LVLMs-Saliency. Extensive experiments across multiple LVLMs demonstrate that our method significantly reduces hallucination rates while preserving fluency and task performance, offering a robust and interpretable solution for enhancing model reliability. Code is available at: https://github.com/zhangbaijin/LVLMs-Saliency

Sensory systems across all modalities and species exhibit adaptation to continuously changing input statistics. Individual neurons have been shown to modulate their response gains so as to maximize information transmission in different stimulus contexts. Experimental measurements have revealed additional, nuanced sensory adaptation effects including changes in response maxima and minima, tuning curve repulsion from the adapter stimulus, and stimulus-driven response decorrelation. Existing explanations of these phenomena rely on changes in inter-neuronal synaptic efficacy, which, while more flexible, are unlikely to operate as rapidly or reversibly as single neuron gain modulations. Using published V1 population adaptation data, we show that propagation of single neuron gain changes in a recurrent network is sufficient to capture the entire set of observed adaptation effects. We propose a novel adaptive efficient coding objective with which single neuron gains are modulated, maximizing the fidelity of the stimulus representation while minimizing overall activity in the network. From this objective, we analytically derive a set of gains that optimize the trade-off between preserving information about the stimulus and conserving metabolic resources. Our model generalizes well-established concepts of single neuron adaptive gain control to recurrent populations, and parsimoniously explains experimental adaptation data.

How different populations visually explore artworks bears on cognitive science and on accessibility design, yet most eye-tracking work in autism has used social scenes rather than art, and has analysed where the eyes land while ignoring when and in what order. We present a comparative free-viewing study across three groups, autistic adults (ASD), trained artists, and neurotypical observers, who each viewed 30 paintings for 15s. We introduce a directed, metric-grounded framework that compares groups along two complementary axes: a spatial axis, in which one group's fixation-density map predicts another's fixations under six saliency metrics (AUC-Judd, NSS, CC, SIM, KL, Information Gain); and a temporal axis, in which individual scanpaths are compared with MultiMatch, ScanMatch, a foveal-disc IoU score (FDISS), and dynamic time warping (DTW). Fixations are extracted uniformly for all groups with a dispersion-threshold algorithm. Three results converge. (i)Artists and neurotypicals are almost indistinguishable in both space (density-map correlation CC=0.96) and time (they form the most alignable scanpath pair), whereas ASD gaze diverges from both. (ii)ASD attention is dissociated: it matches artists' wide spatial exploration (dispersion, explored area) but carries a distinct temporal signature, shorter fixations, less dwell, and the most idiosyncratic (least self-consistent) scanpaths of any group. (iii)ASD gaze is not selectively artist-like on any metric; if anything it is marginally closer to neurotypical. Together these findings indicate that autistic viewing of art is a distinct, group-specific attentional profile in both space and time, and they motivate population-conditioned models of aesthetic attention. We release all analysis code and per-stimulus results.

How neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience. Various studies have suggested plausible solutions for back-propagating error signals through multi-layer networks. These purely functionally motivated models assume distinct neuronal compartments to represent local error signals that determine the sign of synaptic plasticity. However, this explicit error modulation is inconsistent with phenomenological plasticity models in which the sign depends primarily on postsynaptic activity. Here we show how a plausible microcircuit model and Hebbian learning rule derived within an adaptive control theory framework can resolve this discrepancy. Assuming errors are encoded in top-down dis-inhibitory synaptic afferents, we show that error-modulated learning emerges naturally at the circuit level when recurrent inhibition explicitly influences Hebbian plasticity. The same learning rule accounts for experimentally observed plasticity in the absence of inhibition and performs comparably to back-propagation of error (BP) on several non-linearly separable benchmarks. Our findings bridge the gap between functional and experimentally observed plasticity rules and make concrete predictions on inhibitory modulation of excitatory plasticity.

Large multimodal models (LMMs) "see" images by leveraging the attention mechanism between text and visual tokens in the transformer decoder. Ideally, these models should focus on key visual information relevant to the text token. However, recent findings indicate that LMMs have an extraordinary tendency to consistently allocate high attention weights to specific visual tokens, even when these tokens are irrelevant to the corresponding text. In this study, we investigate the property behind the appearance of these irrelevant visual tokens and examine their characteristics. Our findings show that this behavior arises due to the massive activation of certain hidden state dimensions, which resembles the attention sink found in language models. Hence, we refer to this phenomenon as the visual attention sink. In particular, our analysis reveals that removing the irrelevant visual sink tokens does not impact model performance, despite receiving high attention weights. Consequently, we recycle the attention to these tokens as surplus resources, redistributing the attention budget to enhance focus on the image. To achieve this, we introduce Visual Attention Redistribution (VAR), a method that redistributes attention in image-centric heads, which we identify as innately focusing on visual information. VAR can be seamlessly applied across different LMMs to improve performance on a wide range of tasks, including general vision-language tasks, visual hallucination tasks, and vision-centric tasks, all without the need for additional training, models, or inference steps. Experimental results demonstrate that VAR enables LMMs to process visual information more effectively by adjusting their internal attention mechanisms, offering a new direction to enhancing the multimodal capabilities of LMMs.

A striking feature of the human visual system is that it ingests visual information through a series of local foveated glimpses, rather than a single global computation. This makes human vision distinctly different from most popular computer vision models in use today, which input images globally and in a single shot. A natural question therefore is whether local, sequential vision models may provide any fundamental computational benefits in addition to being biologically more plausible than global models. In this work, we investigate this question from the perspective of visual state tracking and length generalization. Inspired by recent studies of length generalization in language models, we study the behavior of vision models trained on simple vision tasks that require the aggregation of local information across an image. Our experiments reveal that, similar to language models, vision models can learn to exploit global shortcuts and thereby fail to generalize over task length or complexity. We also show that recurrent vision policies based on strictly local perception can mitigate these failures, thereby allowing models to generalize on these tasks. Our results show that local attention may be an essential overlooked requirement for robust compositional generalization.

The approximation capability of ANNs and their RNN instantiations, is strongly correlated with the number of parameters packed into these networks. However, the complexity barrier for human understanding, is arguably related to the number of neurons and synapses in the networks, and to the associated nonlinear transformations. In this paper we show that the use of biophysical synapses, as found in LTCs, have two main benefits. First, they allow to pack more parameters for a given number of neurons and synapses. Second, they allow to formulate the nonlinear-network transformation, as a linear system with state-dependent coefficients. Both increase interpretability, as for a given task, they allow to learn a system linear in its input features, that is smaller in size compared to the state of the art. We substantiate the above claims on various time-series prediction tasks, but we believe that our results are applicable to any feedforward or recurrent ANN.

Mamba has recently garnered attention as an effective backbone for vision tasks. However, its underlying mechanism in visual domains remains poorly understood. In this work, we systematically investigate Mamba's representational properties and make three primary contributions. First, we theoretically analyze Mamba's relationship to Softmax and Linear Attention, confirming that it can be viewed as a low-rank approximation of Softmax Attention and thereby bridging the representational gap between Softmax and Linear forms. Second, we introduce a novel binary segmentation metric for activation map evaluation, extending qualitative assessments to a quantitative measure that demonstrates Mamba's capacity to model long-range dependencies. Third, by leveraging DINO for self-supervised pretraining, we obtain clearer activation maps than those produced by standard supervised approaches, highlighting Mamba's potential for interpretability. Notably, our model also achieves a 78.5 percent linear probing accuracy on ImageNet, underscoring its strong performance. We hope this work can provide valuable insights for future investigations of Mamba-based vision architectures.

Block-sparse attention is promising for accelerating long-context LLM pre-filling, yet identifying relevant blocks efficiently remains a bottleneck. Existing methods typically employ coarse-grained attention as a proxy for block importance estimation, but often resort to expensive token-level searching or scoring, resulting in significant selection overhead. In this work, we trace the inaccuracy of standard coarse-grained attention via mean pooling to a theoretical root cause: the interaction between mean pooling and Rotary Positional Embeddings (RoPE). We prove that mean pooling acts as a low-pass filter that induces destructive interference in high-frequency dimensions, effectively creating a "blind spot" for local positional information (e.g., slash patterns). To address this, we introduce Prism, a training-free spectral-aware approach that decomposes block selection into high-frequency and low-frequency branches. By applying energy-based temperature calibration, Prism restores the attenuated positional signals directly from pooled representations, enabling block importance estimation using purely block-level operations, thereby improving efficiency. Extensive evaluations confirm that Prism maintains accuracy parity with full attention while delivering up to 5.1times speedup.

Visual attention modeling, important for interpreting and prioritizing visual stimuli, plays a significant role in applications such as marketing, multimedia, and robotics. Traditional saliency prediction models, especially those based on Convolutional Neural Networks (CNNs) or Transformers, achieve notable success by leveraging large-scale annotated datasets. However, the current state-of-the-art (SOTA) models that use Transformers are computationally expensive. Additionally, separate models are often required for each image type, lacking a unified approach. In this paper, we propose Saliency Unification through Mamba (SUM), a novel approach that integrates the efficient long-range dependency modeling of Mamba with U-Net to provide a unified model for diverse image types. Using a novel Conditional Visual State Space (C-VSS) block, SUM dynamically adapts to various image types, including natural scenes, web pages, and commercial imagery, ensuring universal applicability across different data types. Our comprehensive evaluations across five benchmarks demonstrate that SUM seamlessly adapts to different visual characteristics and consistently outperforms existing models. These results position SUM as a versatile and powerful tool for advancing visual attention modeling, offering a robust solution universally applicable across different types of visual content.

Recent breakthroughs in synaptic-resolution network connectomics have revealed that brain circuits feature fine-scale structural connectivity, such as pairs of correlated synaptic couplings known as second-order motifs. Large-scale recordings of neuronal activity in networks containing nonlinear neurons reveal macroscopic heterogeneous population dynamics throughout the brain. These findings rekindle the inquiry into this intriguing question: Can microscale synaptic structures contribute to macroscopic heterogeneous dynamics and computations in ways that canonical brain circuit models cannot? To answer this question, we create random RNNs with various cell types, nonlinear non-negative neural responses, and arbitrary marginal and second-order correlated synaptic statistics. We derive mean-field low-rank equations for P-population networks in which the pre- and postsynaptic neuronal population identities determine the synaptic and motif strengths. Our framework requires 2P latent dynamic variables with P variables describing mean population activity and P variables capturing within-population variability. Theoretical and simulational results demonstrate that chain motifs induce correlations in synaptic variability, enabling microscopic fluctuations to be integrated and influence mesoscopic mean population dynamics. We apply this framework to reverse engineer network connectivity that recapitulates the heterogeneous activity across the population in the mouse primary visual cortex. By bridging the gap between synaptic organization and nonlinear heterogeneous population dynamics, our results offer a principled approach and testable predictions regarding the relationship between fine-scale connectivity, heterogeneous dynamics, and functional computations.

Visual search is a ubiquitous and often challenging daily task, exemplified by looking for the car keys at home or a friend in a crowd. An intriguing property of some classical search tasks is an asymmetry such that finding a target A among distractors B can be easier than finding B among A. To elucidate the mechanisms responsible for asymmetry in visual search, we propose a computational model that takes a target and a search image as inputs and produces a sequence of eye movements until the target is found. The model integrates eccentricity-dependent visual recognition with target-dependent top-down cues. We compared the model against human behavior in six paradigmatic search tasks that show asymmetry in humans. Without prior exposure to the stimuli or task-specific training, the model provides a plausible mechanism for search asymmetry. We hypothesized that the polarity of search asymmetry arises from experience with the natural environment. We tested this hypothesis by training the model on augmented versions of ImageNet where the biases of natural images were either removed or reversed. The polarity of search asymmetry disappeared or was altered depending on the training protocol. This study highlights how classical perceptual properties can emerge in neural network models, without the need for task-specific training, but rather as a consequence of the statistical properties of the developmental diet fed to the model. All source code and data are publicly available at https://github.com/kreimanlab/VisualSearchAsymmetry.

Statistical whitening transformations play a fundamental role in many computational systems, and may also play an important role in biological sensory systems. Existing neural circuit models of adaptive whitening operate by modifying synaptic interactions; however, such modifications would seem both too slow and insufficiently reversible. Motivated by the extensive neuroscience literature on gain modulation, we propose an alternative model that adaptively whitens its responses by modulating the gains of individual neurons. Starting from a novel whitening objective, we derive an online algorithm that whitens its outputs by adjusting the marginal variances of an overcomplete set of projections. We map the algorithm onto a recurrent neural network with fixed synaptic weights and gain-modulating interneurons. We demonstrate numerically that sign-constraining the gains improves robustness of the network to ill-conditioned inputs, and a generalization of the circuit achieves a form of local whitening in convolutional populations, such as those found throughout the visual or auditory systems.

In some medical imaging tasks and other settings where only small parts of the image are informative for the classification task, traditional CNNs can sometimes struggle to generalise. Manually annotated Regions of Interest (ROI) are sometimes used to isolate the most informative parts of the image. However, these are expensive to collect and may vary significantly across annotators. To overcome these issues, we propose a framework that employs saliency maps to obtain soft spatial attention masks that modulate the image features at different scales. We refer to our method as Adversarial Counterfactual Attention (ACAT). ACAT increases the baseline classification accuracy of lesions in brain CT scans from 71.39% to 72.55% and of COVID-19 related findings in lung CT scans from 67.71% to 70.84% and exceeds the performance of competing methods. We investigate the best way to generate the saliency maps employed in our architecture and propose a way to obtain them from adversarially generated counterfactual images. They are able to isolate the area of interest in brain and lung CT scans without using any manual annotations. In the task of localising the lesion location out of 6 possible regions, they obtain a score of 65.05% on brain CT scans, improving the score of 61.29% obtained with the best competing method.

We can better understand deep neural networks by identifying which features each of their neurons have learned to detect. To do so, researchers have created Deep Visualization techniques including activation maximization, which synthetically generates inputs (e.g. images) that maximally activate each neuron. A limitation of current techniques is that they assume each neuron detects only one type of feature, but we know that neurons can be multifaceted, in that they fire in response to many different types of features: for example, a grocery store class neuron must activate either for rows of produce or for a storefront. Previous activation maximization techniques constructed images without regard for the multiple different facets of a neuron, creating inappropriate mixes of colors, parts of objects, scales, orientations, etc. Here, we introduce an algorithm that explicitly uncovers the multiple facets of each neuron by producing a synthetic visualization of each of the types of images that activate a neuron. We also introduce regularization methods that produce state-of-the-art results in terms of the interpretability of images obtained by activation maximization. By separately synthesizing each type of image a neuron fires in response to, the visualizations have more appropriate colors and coherent global structure. Multifaceted feature visualization thus provides a clearer and more comprehensive description of the role of each neuron.

Multimodal large language models (MLLMs) have achieved remarkable progress on various vision-language tasks, yet their visual perception remains limited. Humans, in comparison, perceive complex scenes efficiently by dynamically scanning and focusing on salient regions in a sequential "blink-like" process. Motivated by this strategy, we first investigate whether MLLMs exhibit similar behavior. Our pilot analysis reveals that MLLMs naturally attend to different visual regions across layers and that selectively allocating more computation to salient tokens can enhance visual perception. Building on this insight, we propose Blink, a dynamic visual token resolution framework that emulates the human-inspired process within a single forward pass. Specifically, Blink includes two modules: saliency-guided scanning and dynamic token resolution. It first estimates the saliency of visual tokens in each layer based on the attention map, and extends important tokens through a plug-and-play token super-resolution (TokenSR) module. In the next layer, it drops the extended tokens when they lose focus. This dynamic mechanism balances broad exploration and fine-grained focus, thereby enhancing visual perception adaptively and efficiently. Extensive experiments validate Blink, demonstrating its effectiveness in enhancing visual perception and multimodal understanding.

Convolutional Neural Networks (CNNs) have demonstrated superiority in learning patterns, but are sensitive to label noises and may overfit noisy labels during training. The early stopping strategy averts updating CNNs during the early training phase and is widely employed in the presence of noisy labels. Motivated by biological findings that the amplitude spectrum (AS) and phase spectrum (PS) in the frequency domain play different roles in the animal's vision system, we observe that PS, which captures more semantic information, can increase the robustness of DNNs to label noise, more so than AS can. We thus propose early stops at different times for AS and PS by disentangling the features of some layer(s) into AS and PS using Discrete Fourier Transform (DFT) during training. Our proposed Phase-AmplituDe DisentangLed Early Stopping (PADDLES) method is shown to be effective on both synthetic and real-world label-noise datasets. PADDLES outperforms other early stopping methods and obtains state-of-the-art performance.

A major goal of neuroscience is to understand brain computations during visual processing in naturalistic settings. A dominant approach is to use image-computable deep neural networks trained with different task objectives as a basis for linear encoding models. However, in addition to requiring tuning a large number of parameters, the linear encoding approach ignores the structure of the feature maps both in the brain and the models. Recently proposed alternatives have focused on decomposing the linear mapping to spatial and feature components but focus on finding static receptive fields for units that are applicable only in early visual areas. In this work, we employ the attention mechanism used in the transformer architecture to study how retinotopic visual features can be dynamically routed to category-selective areas in high-level visual processing. We show that this computational motif is significantly more powerful than alternative methods in predicting brain activity during natural scene viewing, across different feature basis models and modalities. We also show that this approach is inherently more interpretable, without the need to create importance maps, by interpreting the attention routing signal for different high-level categorical areas. Our approach proposes a mechanistic model of how visual information from retinotopic maps can be routed based on the relevance of the input content to different category-selective regions.

A growing literature in computational neuroscience leverages gradient descent and learning algorithms that approximate it to study synaptic plasticity in the brain. However, the vast majority of this work ignores a critical underlying assumption: the choice of distance for synaptic changes - i.e. the geometry of synaptic plasticity. Gradient descent assumes that the distance is Euclidean, but many other distances are possible, and there is no reason that biology necessarily uses Euclidean geometry. Here, using the theoretical tools provided by mirror descent, we show that the distribution of synaptic weights will depend on the geometry of synaptic plasticity. We use these results to show that experimentally-observed log-normal weight distributions found in several brain areas are not consistent with standard gradient descent (i.e. a Euclidean geometry), but rather with non-Euclidean distances. Finally, we show that it should be possible to experimentally test for different synaptic geometries by comparing synaptic weight distributions before and after learning. Overall, our work shows that the current paradigm in theoretical work on synaptic plasticity that assumes Euclidean synaptic geometry may be misguided and that it should be possible to experimentally determine the true geometry of synaptic plasticity in the brain.

Saliency maps can explain a neural model's predictions by identifying important input features. They are difficult to interpret for laypeople, especially for instances with many features. In order to make them more accessible, we formalize the underexplored task of translating saliency maps into natural language and compare methods that address two key challenges of this approach -- what and how to verbalize. In both automatic and human evaluation setups, using token-level attributions from text classification tasks, we compare two novel methods (search-based and instruction-based verbalizations) against conventional feature importance representations (heatmap visualizations and extractive rationales), measuring simulatability, faithfulness, helpfulness and ease of understanding. Instructing GPT-3.5 to generate saliency map verbalizations yields plausible explanations which include associations, abstractive summarization and commonsense reasoning, achieving by far the highest human ratings, but they are not faithfully capturing numeric information and are inconsistent in their interpretation of the task. In comparison, our search-based, model-free verbalization approach efficiently completes templated verbalizations, is faithful by design, but falls short in helpfulness and simulatability. Our results suggest that saliency map verbalization makes feature attribution explanations more comprehensible and less cognitively challenging to humans than conventional representations.

The human brain processes dynamic visual input through hierarchically organized, functionally specialized regions. While recent in silico brain encoding models can synthesize optimal stimuli to probe selectivity in different brain regions, prior work has been largely limited to static images, leaving dynamic visual processing underexplored. We introduce a novel neural-guided video synthesis framework that generates stimuli optimized for target brain regions across visual cortex. Our method performs evolutionary search over a structured prompt space, guided by a dynamic encoding model that predicts voxel-level responses to video inputs. By maximizing predicted activity for a target ROI, the framework efficiently discovers hyper-activating dynamic stimuli that consistently surpass handcrafted localizer videos. The synthesized videos recover known selectivities across ventral, dorsal, and lateral pathways, and further reveal systematic differences in sensitivity to temporal dynamics. A searchlight analysis provides new insight into the progression toward increasingly complex social-dynamic features along the lateral stream, further supported by probing with synthesized abstract, non-naturalistic stimuli. Taken together, our framework enables in silico exploration of dynamic visual selectivity, with new predictions for in vivo experiments

Large Vision-Language Models (LVLMs) generate contextually relevant responses by jointly interpreting visual and textual inputs. However, our finding reveals they often mistakenly perceive text inputs lacking visual evidence as being part of the image, leading to erroneous responses. In light of this finding, we probe whether LVLMs possess an internal capability to determine if textual concepts are grounded in the image, and discover a specific subset of Feed-Forward Network (FFN) neurons, termed Visual Absence-aware (VA) neurons, that consistently signal the visual absence through a distinctive activation pattern. Leveraging these patterns, we develop a detection module that systematically classifies whether an input token is visually grounded. Guided by its prediction, we propose a method to refine the outputs by reinterpreting question prompts or replacing the detected absent tokens during generation. Extensive experiments show that our method effectively mitigates the models' tendency to falsely presume the visual presence of text input and its generality across various LVLMs.

Saliency methods have emerged as a popular tool to highlight features in an input deemed relevant for the prediction of a learned model. Several saliency methods have been proposed, often guided by visual appeal on image data. In this work, we propose an actionable methodology to evaluate what kinds of explanations a given method can and cannot provide. We find that reliance, solely, on visual assessment can be misleading. Through extensive experiments we show that some existing saliency methods are independent both of the model and of the data generating process. Consequently, methods that fail the proposed tests are inadequate for tasks that are sensitive to either data or model, such as, finding outliers in the data, explaining the relationship between inputs and outputs that the model learned, and debugging the model. We interpret our findings through an analogy with edge detection in images, a technique that requires neither training data nor model. Theory in the case of a linear model and a single-layer convolutional neural network supports our experimental findings.

Understanding the hidden mechanisms behind human's visual perception is a fundamental question in neuroscience. To that end, investigating into the neural responses of human mind activities, such as functional Magnetic Resonance Imaging (fMRI), has been a significant research vehicle. However, analyzing fMRI signals is challenging, costly, daunting, and demanding for professional training. Despite remarkable progress in fMRI analysis, existing approaches are limited to generating 2D images and far away from being biologically meaningful and practically useful. Under this insight, we propose to generate visually plausible and functionally more comprehensive 3D outputs decoded from brain signals, enabling more sophisticated modeling of fMRI data. Conceptually, we reformulate this task as a {\em fMRI conditioned 3D object generation} problem. We design a novel 3D object representation learning method, Brain3D, that takes as input the fMRI data of a subject who was presented with a 2D image, and yields as output the corresponding 3D object images. The key capabilities of this model include tackling the noises with high-level semantic signals and a two-stage architecture design for progressive high-level information integration. Extensive experiments validate the superior capability of our model over previous state-of-the-art 3D object generation methods. Importantly, we show that our model captures the distinct functionalities of each region of human vision system as well as their intricate interplay relationships, aligning remarkably with the established discoveries in neuroscience. Further, preliminary evaluations indicate that Brain3D can successfully identify the disordered brain regions in simulated scenarios, such as V1, V2, V3, V4, and the medial temporal lobe (MTL) within the human visual system. Our data and code will be available at https://brain-3d.github.io/.

Attending to what is relevant is fundamental to both the mammalian brain and modern machine learning models such as Transformers. Yet, determining relevance remains a core challenge, traditionally offloaded to learning algorithms like backpropagation. Inspired by recent cellular neurobiological evidence linking neocortical pyramidal cells to distinct mental states, this work shows how models (e.g., Transformers) can emulate high-level perceptual processing and awake thought (imagination) states to pre-select relevant information before applying attention. Triadic neuronal-level modulation loops among questions (Q), clues (keys, K), and hypotheses (values, V) enable diverse, deep, parallel reasoning chains at the representation level and allow a rapid shift from initial biases to refined understanding. This leads to orders-of-magnitude faster learning with significantly reduced computational demand (e.g., fewer heads, layers, and tokens), at an approximate cost of O(N), where N is the number of input tokens. Results span reinforcement learning (e.g., CarRacing in a high-dimensional visual setup), computer vision, and natural language question answering.

Predicting salient regions in natural images requires the detection of objects that are present in a scene. To develop robust representations for this challenging task, high-level visual features at multiple spatial scales must be extracted and augmented with contextual information. However, existing models aimed at explaining human fixation maps do not incorporate such a mechanism explicitly. Here we propose an approach based on a convolutional neural network pre-trained on a large-scale image classification task. The architecture forms an encoder-decoder structure and includes a module with multiple convolutional layers at different dilation rates to capture multi-scale features in parallel. Moreover, we combine the resulting representations with global scene information for accurately predicting visual saliency. Our model achieves competitive and consistent results across multiple evaluation metrics on two public saliency benchmarks and we demonstrate the effectiveness of the suggested approach on five datasets and selected examples. Compared to state of the art approaches, the network is based on a lightweight image classification backbone and hence presents a suitable choice for applications with limited computational resources, such as (virtual) robotic systems, to estimate human fixations across complex natural scenes.

Human visual reasoning typically follows a coarse-to-fine attention process, starting from global scene understanding and gradually focusing on question-relevant regions. However, multimodal large language models may deviate from this pattern due to attention drift and the underutilization of visual evidence, which can lead to hallucinations. To mitigate these issues, this study proposes a Dual-Indicator Guided Contrastive Alignment (DICA), which tracks two information-theoretic indicators during inference: Visual Attention Entropy (VAE), which reflects the concentration of visual attention, and Output Image Correlation (OIC), which measures the dependence of generated outputs on the visual input. An abnormal increase in VAE or a decrease in OIC corresponds to different failure modes, which trigger targeted contrastive alignment to restore visual grounding. Experimental results across multiple benchmarks demonstrate that DICA consistently outperforms existing approaches and substantially reduces hallucinations, highlighting the effectiveness of indicator-driven intervention in improving multimodal inference reliability. The code is publicly available at https://github.com/BGWH123/DICA/.

Over the past decade, predictive modeling of neural responses in the primate visual system has advanced significantly, largely driven by various DNN approaches. These include models optimized directly for visual recognition, cross-modal alignment through contrastive objectives, neural response prediction from scratch, and large language model embeddings.Likewise, different readout mechanisms, ranging from fully linear to spatial-feature factorized methods have been explored for mapping network activations to neural responses. Despite the diversity of these approaches, it remains unclear which method performs best across different visual regions. In this study, we systematically compare these approaches for modeling the human visual system and investigate alternative strategies to improve response predictions. Our findings reveal that for early to mid-level visual areas, response-optimized models with visual inputs offer superior prediction accuracy, while for higher visual regions, embeddings from LLMs based on detailed contextual descriptions of images and task-optimized models pretrained on large vision datasets provide the best fit. Through comparative analysis of these modeling approaches, we identified three distinct regions in the visual cortex: one sensitive primarily to perceptual features of the input that are not captured by linguistic descriptions, another attuned to fine-grained visual details representing semantic information, and a third responsive to abstract, global meanings aligned with linguistic content. We also highlight the critical role of readout mechanisms, proposing a novel scheme that modulates receptive fields and feature maps based on semantic content, resulting in an accuracy boost of 3-23% over existing SOTAs for all models and brain regions. Together, these findings offer key insights into building more precise models of the visual system.

Vision-Language Models (VLMs) have demonstrated remarkable progress in multimodal tasks, but remain susceptible to hallucinations, where generated text deviates from the underlying visual content. Existing hallucination detection methods primarily rely on output logits or external verification tools, often overlooking their internal mechanisms. In this work, we investigate the outputs of internal attention heads, postulating that specific heads carry the primary signals for truthful generation.However, directly probing these high-dimensional states is challenging due to the entanglement of visual-linguistic syntax and noise. To address this, we propose VIB-Probe, a novel hallucination detection and mitigation framework leveraging the Variational Information Bottleneck (VIB) theory. Our method extracts discriminative patterns across layers and heads while filtering out semantic nuisances through the information bottleneck principle. Furthermore, by leveraging the gradients of our VIB probe, we identify attention heads with strong causal influence on hallucinations and introduce an inference-time intervention strategy for hallucination mitigation. Extensive experiments across diverse benchmarks demonstrate that VIB-Probe significantly outperforms existing baselines in both settings. Our code will be made publicly available.

The structure of biological neural circuits-modular, hierarchical, and sparsely interconnected-reflects an efficient trade-off between wiring cost, functional specialization, and robustness. These principles offer valuable insights for artificial neural network (ANN) design, especially as networks grow in depth and scale. Sparsity, in particular, has been widely explored for reducing memory and computation, improving speed, and enhancing generalization. Motivated by systems neuroscience findings, we explore how patterns of functional connectivity in the mouse visual cortex-specifically, ensemble-to-ensemble communication, can inform ANN design. We introduce G2GNet, a novel architecture that imposes sparse, modular connectivity across feedforward layers. Despite having significantly fewer parameters than fully connected models, G2GNet achieves superior accuracy on standard vision benchmarks. To our knowledge, this is the first architecture to incorporate biologically observed functional connectivity patterns as a structural bias in ANN design. We complement this static bias with a dynamic sparse training (DST) mechanism that prunes and regrows edges during training. We also propose a Hebbian-inspired rewiring rule based on activation correlations, drawing on principles of biological plasticity. G2GNet achieves up to 75% sparsity while improving accuracy by up to 4.3% on benchmarks, including Fashion-MNIST, CIFAR-10, and CIFAR-100, outperforming dense baselines with far fewer computations.

Over the past few years, deep neural models have made considerable advances in image quality assessment (IQA). However, the underlying reasons for their success remain unclear, owing to the complex nature of deep neural networks. IQA aims to describe how the human visual system (HVS) works and to create its efficient approximations. On the other hand, Saliency Prediction task aims to emulate HVS via determining areas of visual interest. Thus, we believe that saliency plays a crucial role in human perception. In this work, we conduct an empirical study that reveals the relation between IQA and Saliency Prediction tasks, demonstrating that the former incorporates knowledge of the latter. Moreover, we introduce a novel SACID dataset of saliency-aware compressed images and conduct a large-scale comparison of classic and neural-based IQA methods. All supplementary code and data will be available at the time of publication.

As machine learning algorithms are increasingly applied to high impact yet high risk tasks, such as medical diagnosis or autonomous driving, it is critical that researchers can explain how such algorithms arrived at their predictions. In recent years, a number of image saliency methods have been developed to summarize where highly complex neural networks "look" in an image for evidence for their predictions. However, these techniques are limited by their heuristic nature and architectural constraints. In this paper, we make two main contributions: First, we propose a general framework for learning different kinds of explanations for any black box algorithm. Second, we specialise the framework to find the part of an image most responsible for a classifier decision. Unlike previous works, our method is model-agnostic and testable because it is grounded in explicit and interpretable image perturbations.

We present a simple approach to make pre-trained Vision Transformers (ViTs) interpretable for fine-grained analysis, aiming to identify and localize the traits that distinguish visually similar categories, such as bird species. Pre-trained ViTs, such as DINO, have demonstrated remarkable capabilities in extracting localized, discriminative features. However, saliency maps like Grad-CAM often fail to identify these traits, producing blurred, coarse heatmaps that highlight entire objects instead. We propose a novel approach, Prompt Class Attention Map (Prompt-CAM), to address this limitation. Prompt-CAM learns class-specific prompts for a pre-trained ViT and uses the corresponding outputs for classification. To correctly classify an image, the true-class prompt must attend to unique image patches not present in other classes' images (i.e., traits). As a result, the true class's multi-head attention maps reveal traits and their locations. Implementation-wise, Prompt-CAM is almost a ``free lunch,'' requiring only a modification to the prediction head of Visual Prompt Tuning (VPT). This makes Prompt-CAM easy to train and apply, in stark contrast to other interpretable methods that require designing specific models and training processes. Extensive empirical studies on a dozen datasets from various domains (e.g., birds, fishes, insects, fungi, flowers, food, and cars) validate the superior interpretation capability of Prompt-CAM. The source code and demo are available at https://github.com/Imageomics/Prompt_CAM.

Recent work has shown that the attention maps of the widely popular DINOv2 model exhibit artifacts, which hurt both model interpretability and performance on dense image tasks. These artifacts emerge due to the model repurposing patch tokens with redundant local information for the storage of global image information. To address this problem, additional register tokens have been incorporated in which the model can store such information instead. We carefully examine the influence of these register tokens on the relationship between global and local image features, showing that while register tokens yield cleaner attention maps, these maps do not accurately reflect the integration of local image information in large models. Instead, global information is dominated by information extracted from register tokens, leading to a disconnect between local and global features. Inspired by these findings, we show that the [CLS] token itself leads to a very similar phenomenon in models without explicit register tokens. Our work shows that care must be taken when interpreting attention maps of large ViTs. Further, by clearly attributing the faulty behavior to register and [CLS] tokens, we show a path towards more interpretable vision models.

Understanding the functional organization of higher visual cortex is a central focus in neuroscience. Past studies have primarily mapped the visual and semantic selectivity of neural populations using hand-selected stimuli, which may potentially bias results towards pre-existing hypotheses of visual cortex functionality. Moving beyond conventional approaches, we introduce a data-driven method that generates natural language descriptions for images predicted to maximally activate individual voxels of interest. Our method -- Semantic Captioning Using Brain Alignments ("BrainSCUBA") -- builds upon the rich embedding space learned by a contrastive vision-language model and utilizes a pre-trained large language model to generate interpretable captions. We validate our method through fine-grained voxel-level captioning across higher-order visual regions. We further perform text-conditioned image synthesis with the captions, and show that our images are semantically coherent and yield high predicted activations. Finally, to demonstrate how our method enables scientific discovery, we perform exploratory investigations on the distribution of "person" representations in the brain, and discover fine-grained semantic selectivity in body-selective areas. Unlike earlier studies that decode text, our method derives voxel-wise captions of semantic selectivity. Our results show that BrainSCUBA is a promising means for understanding functional preferences in the brain, and provides motivation for further hypothesis-driven investigation of visual cortex.

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors at different times. We introduce an unsupervised approach to learn the dynamic affinities between neurons in live, behaving animals, and to reveal which communities form among neurons at different times. The inference occurs in two major steps. First, pairwise non-linear affinities between neuronal traces from brain-wide calcium activity are organized by non-negative tensor factorization (NTF). Each factor specifies which groups of neurons are most likely interacting for an inferred interval in time, and for which animals. Finally, a generative model that allows for weighted community detection is applied to the functional motifs produced by NTF to reveal a dynamic functional connectome. Since time codes the different experimental variables (e.g., application of chemical stimuli), this provides an atlas of neural motifs active during separate stages of an experiment (e.g., stimulus application or spontaneous behaviors). Results from our analysis are experimentally validated, confirming that our method is able to robustly predict causal interactions between neurons to generate behavior. Code is available at https://github.com/dyballa/dynamic-connectomes.

We introduce a new tool for interpreting neural net responses, namely full-gradients, which decomposes the neural net response into input sensitivity and per-neuron sensitivity components. This is the first proposed representation which satisfies two key properties: completeness and weak dependence, which provably cannot be satisfied by any saliency map-based interpretability method. For convolutional nets, we also propose an approximate saliency map representation, called FullGrad, obtained by aggregating the full-gradient components. We experimentally evaluate the usefulness of FullGrad in explaining model behaviour with two quantitative tests: pixel perturbation and remove-and-retrain. Our experiments reveal that our method explains model behaviour correctly, and more comprehensively than other methods in the literature. Visual inspection also reveals that our saliency maps are sharper and more tightly confined to object regions than other methods.

This study addresses the issue observed in Large Vision Language Models (LVLMs), where excessive attention on a few image tokens, referred to as blind tokens, leads to hallucinatory responses in tasks requiring fine-grained understanding of visual objects. We found that tokens receiving lower attention weights often hold essential information for identifying nuanced object details -- ranging from merely recognizing object existence to identifying their attributes (color, position, etc.) and understanding their relationships. To counteract the over-emphasis on blind tokens and to accurately respond to user queries, we introduce a technique called Attentional Vision Calibration (AVC). During the decoding phase, AVC identifies blind tokens by analyzing the image-related attention distribution. It then dynamically adjusts the logits for the next token prediction by contrasting the logits conditioned on the original visual tokens with those conditioned on the blind tokens. This effectively lowers the dependency on blind tokens and promotes a more balanced consideration of all tokens. We validate AVC on benchmarks such as POPE, MME, and AMBER, where it consistently outperforms existing decoding techniques in mitigating object hallucinations in LVLMs.

Excluding irrelevant features in a pattern recognition task plays an important role in maintaining a simpler machine learning model and optimizing the computational efficiency. Nowadays with the rise of large scale datasets, feature selection is in great demand as it becomes a central issue when facing high-dimensional datasets. The present study provides a new measure of saliency for features by employing a Sensitivity Analysis (SA) technique called the extended Fourier amplitude sensitivity test, and a well-trained Feedforward Neural Network (FNN) model, which ultimately leads to the selection of a promising optimal feature subset. Ideas of the paper are mainly demonstrated based on adopting FNN model for feature selection in classification problems. But in the end, a generalization framework is discussed in order to give insights into the usage in regression problems as well as expressing how other function approximate models can be deployed. Effectiveness of the proposed method is verified by result analysis and data visualization for a series of experiments over several well-known datasets drawn from UCI machine learning repository.

Existing Large Vision-Language Models (LVLMs) exhibit insufficient visual attention, leading to hallucinations. To alleviate this problem, some previous studies adjust and amplify visual attention. These methods present a limitation that boosting attention for all visual tokens inevitably increases attention to task irrelevant tokens. To tackle this challenge, we propose a training free attentional intervention algorithm to enhance the attention of task-relevant tokens based on the argument that task-relevant tokens generally demonstrate high visual-textual similarities. Specifically, the vision-text cross-attention submatrices, which represent visual-textual correlations, are extracted to construct the reweighting matrices to reallocate attention. Besides, to enhance the contribution of visual tokens, we inject visual attention values into the beam search decoding to identify solutions with higher visual attention. Extensive experiments demonstrate that this method significantly reduces hallucinations across mainstream LVLMs, while preserving the accuracy and coherence of generated content.

Attention mechanisms are a central property of cognitive systems allowing them to selectively deploy cognitive resources in a flexible manner. Attention has been long studied in the neurosciences and there are numerous phenomenological models that try to capture its core properties. Recently attentional mechanisms have become a dominating architectural choice of machine learning and are the central innovation of Transformers. The dominant intuition and formalism underlying their development has drawn on ideas of keys and queries in database management systems. In this work, we propose an alternative Bayesian foundation for attentional mechanisms and show how this unifies different attentional architectures in machine learning. This formulation allows to to identify commonality across different attention ML architectures as well as suggest a bridge to those developed in neuroscience. We hope this work will guide more sophisticated intuitions into the key properties of attention architectures and suggest new ones.

Vision-Language Models (VLMs) have been shown to be blind, often underutilizing their visual inputs even on tasks that require visual reasoning. In this work, we demonstrate that VLMs are selectively blind. They modulate the amount of attention applied to visual inputs based on linguistic framing even when alternative framings demand identical visual reasoning. Using visual attention as a probe, we quantify how framing alters both the amount and distribution of attention over the image. Constrained framings, such as multiple choice and yes/no, induce substantially lower attention to image context compared to open-ended, reduce focus on task-relevant regions, and shift attention towards uninformative tokens. We further demonstrate that this attention misallocation is the principal cause of degraded accuracy and cross-framing inconsistency. Building on this mechanistic insight, we introduce a lightweight prompt-tuning method using learnable tokens that encourages the robust, visually grounded attention patterns observed in open-ended settings, improving visual grounding and improving performance across framings.

Spiking Neural Networks (SNNs) are well known as a promising energy-efficient alternative to conventional artificial neural networks. Subject to the preconceived impression that SNNs are sparse firing, the analysis and optimization of inherent redundancy in SNNs have been largely overlooked, thus the potential advantages of spike-based neuromorphic computing in accuracy and energy efficiency are interfered. In this work, we pose and focus on three key questions regarding the inherent redundancy in SNNs. We argue that the redundancy is induced by the spatio-temporal invariance of SNNs, which enhances the efficiency of parameter utilization but also invites lots of noise spikes. Further, we analyze the effect of spatio-temporal invariance on the spatio-temporal dynamics and spike firing of SNNs. Then, motivated by these analyses, we propose an Advance Spatial Attention (ASA) module to harness SNNs' redundancy, which can adaptively optimize their membrane potential distribution by a pair of individual spatial attention sub-modules. In this way, noise spike features are accurately regulated. Experimental results demonstrate that the proposed method can significantly drop the spike firing with better performance than state-of-the-art SNN baselines. Our code is available in https://github.com/BICLab/ASA-SNN.

Recently, many methods to interpret and visualize deep neural network predictions have been proposed and significant progress has been made. However, a more class-discriminative and visually pleasing explanation is required. Thus, this paper proposes a region-based approach that estimates feature importance in terms of appropriately segmented regions. By fusing the saliency maps generated from multi-scale segmentations, a more class-discriminative and visually pleasing map is obtained. We incorporate this regional multi-scale concept into a prediction difference method that is model-agnostic. An input image is segmented in several scales using the super-pixel method, and exclusion of a region is simulated by sampling a normal distribution constructed using the boundary prior. The experimental results demonstrate that the regional multi-scale method produces much more class-discriminative and visually pleasing saliency maps.

Large vision-language models (LVLMs) have made substantial progress in integrating large language models (LLMs) with visual inputs, enabling advanced multimodal reasoning. Despite their success, a persistent challenge is hallucination-where generated text fails to accurately reflect visual content-undermining both accuracy and reliability. Existing methods focus on alignment training or decoding refinements but primarily address symptoms at the generation stage without probing the underlying causes. In this work, we investigate the internal mechanisms driving hallucination in LVLMs, with an emphasis on the multi-head attention module. Specifically, we introduce Vision-aware Head Divergence (VHD), a metric that quantifies the sensitivity of attention head outputs to visual context. Based on this, our findings reveal the presence of vision-aware attention heads that are more attuned to visual information; however, the model's overreliance on its prior language patterns is closely related to hallucinations. Building on these insights, we propose Vision-aware Head Reinforcement (VHR), a training-free approach to mitigate hallucination by enhancing the role of vision-aware attention heads. Extensive experiments demonstrate that our method achieves superior performance compared to state-of-the-art approaches in mitigating hallucinations, while maintaining high efficiency with negligible additional time overhead.

Identifying cell types and understanding their functional properties is crucial for unraveling the mechanisms underlying perception and cognition. In the retina, functional types can be identified by carefully selected stimuli, but this requires expert domain knowledge and biases the procedure towards previously known cell types. In the visual cortex, it is still unknown what functional types exist and how to identify them. Thus, for unbiased identification of the functional cell types in retina and visual cortex, new approaches are needed. Here we propose an optimization-based clustering approach using deep predictive models to obtain functional clusters of neurons using Most Discriminative Stimuli (MDS). Our approach alternates between stimulus optimization with cluster reassignment akin to an expectation-maximization algorithm. The algorithm recovers functional clusters in mouse retina, marmoset retina and macaque visual area V4. This demonstrates that our approach can successfully find discriminative stimuli across species, stages of the visual system and recording techniques. The resulting most discriminative stimuli can be used to assign functional cell types fast and on the fly, without the need to train complex predictive models or show a large natural scene dataset, paving the way for experiments that were previously limited by experimental time. Crucially, MDS are interpretable: they visualize the distinctive stimulus patterns that most unambiguously identify a specific type of neuron.

The human brain is autonomously active, being characterized by a self-sustained neural activity which would be present even in the absence of external sensory stimuli. Here we study the interrelation between the self-sustained activity in autonomously active recurrent neural nets and external sensory stimuli. There is no a priori semantical relation between the influx of external stimuli and the patterns generated internally by the autonomous and ongoing brain dynamics. The question then arises when and how are semantic correlations between internal and external dynamical processes learned and built up? We study this problem within the paradigm of transient state dynamics for the neural activity in recurrent neural nets, i.e. for an autonomous neural activity characterized by an infinite time-series of transiently stable attractor states. We propose that external stimuli will be relevant during the sensitive periods, {\it viz} the transition period between one transient state and the subsequent semi-stable attractor. A diffusive learning signal is generated unsupervised whenever the stimulus influences the internal dynamics qualitatively. For testing we have presented to the model system stimuli corresponding to the bars and stripes problem. We found that the system performs a non-linear independent component analysis on its own, being continuously and autonomously active. This emergent cognitive capability results here from a general principle for the neural dynamics, the competition between neural ensembles.

In visual-based Reinforcement Learning (RL), agents often struggle to generalize well to environmental variations in the state space that were not observed during training. The variations can arise in both task-irrelevant features, such as background noise, and task-relevant features, such as robot configurations, that are related to the optimal decisions. To achieve generalization in both situations, agents are required to accurately understand the impact of changed features on the decisions, i.e., establishing the true associations between changed features and decisions in the policy model. However, due to the inherent correlations among features in the state space, the associations between features and decisions become entangled, making it difficult for the policy to distinguish them. To this end, we propose Saliency-Guided Features Decorrelation (SGFD) to eliminate these correlations through sample reweighting. Concretely, SGFD consists of two core techniques: Random Fourier Functions (RFF) and the saliency map. RFF is utilized to estimate the complex non-linear correlations in high-dimensional images, while the saliency map is designed to identify the changed features. Under the guidance of the saliency map, SGFD employs sample reweighting to minimize the estimated correlations related to changed features, thereby achieving decorrelation in visual RL tasks. Our experimental results demonstrate that SGFD can generalize well on a wide range of test environments and significantly outperforms state-of-the-art methods in handling both task-irrelevant variations and task-relevant variations.

Many papers have shown that attention heads work in conjunction with each other to perform complex tasks. It's frequently assumed that communication between attention heads is via the addition of specific features to token residuals. In this work we seek to isolate and identify the features used to effect communication and coordination among attention heads in GPT-2 small. Our key leverage on the problem is to show that these features are very often sparsely coded in the singular vectors of attention head matrices. We characterize the dimensionality and occurrence of these signals across the attention heads in GPT-2 small when used for the Indirect Object Identification (IOI) task. The sparse encoding of signals, as provided by attention head singular vectors, allows for efficient separation of signals from the residual background and straightforward identification of communication paths between attention heads. We explore the effectiveness of this approach by tracing portions of the circuits used in the IOI task. Our traces reveal considerable detail not present in previous studies, shedding light on the nature of redundant paths present in GPT-2. And our traces go beyond previous work by identifying features used to communicate between attention heads when performing IOI.

Human sketch has already proved its worth in various visual understanding tasks (e.g., retrieval, segmentation, image-captioning, etc). In this paper, we reveal a new trait of sketches - that they are also salient. This is intuitive as sketching is a natural attentive process at its core. More specifically, we aim to study how sketches can be used as a weak label to detect salient objects present in an image. To this end, we propose a novel method that emphasises on how "salient object" could be explained by hand-drawn sketches. To accomplish this, we introduce a photo-to-sketch generation model that aims to generate sequential sketch coordinates corresponding to a given visual photo through a 2D attention mechanism. Attention maps accumulated across the time steps give rise to salient regions in the process. Extensive quantitative and qualitative experiments prove our hypothesis and delineate how our sketch-based saliency detection model gives a competitive performance compared to the state-of-the-art.

Recent studies show that LLM hidden states encode reward-related information, such as answer correctness and model confidence. However, existing approaches typically fit black-box probes on the full hidden states, offering little insight into how this information is structured across neurons. In this paper, we show that reward-related information is concentrated in a sparse subset of neurons. Using simple probing, we identify two types of neurons: value neurons, whose activations predict state value, and dopamine neurons, whose activations encode step-level temporal difference (TD) errors. Together, these neurons form a sparse reward subsystem within LLM hidden states. These names are drawn by analogy with neuroscience, where value neurons and dopamine neurons in the biological reward subsystem also encode value and reward prediction errors, respectively. We demonstrate that value neurons are robust and transferable across diverse datasets and models, and provide causal evidence that they encode reward-related information. Finally, we show applications of the reward subsystem: value neurons serve as effective predictors of model confidence, and dopamine neurons can function as a process reward model (PRM) to guide inference-time search.

Attractor dynamics are a fundamental computational motif in neural circuits, supporting diverse cognitive functions through stable, self-sustaining patterns of neural activity. In these lecture notes, we review four key examples that demonstrate how autoassociative neural network models can elucidate the computational mechanisms underlying attractor-based information processing in biological neural systems performing cognitive functions. Drawing on empirical evidence, we explore hippocampal spatial representations, visual classification in the inferotemporal cortex, perceptual adaptation and priming, and working-memory biases shaped by sensory history. Across these domains, attractor network models reveal common computational principles and provide analytical insights into how experience shapes neural activity and behavior. Our synthesis underscores the value of attractor models as powerful tools for probing the neural basis of cognition and behavior.

Understanding what individual neurons encode is a core question in neuroscience. In primary visual cortex (V1), mathematical models (e.g., Gabor functions) capture neural selectivity, but no comparable framework exists for higher areas. We show that natural language can fill this role: across macaque V1 and V4, the selectivity of most neurons is captured by concise, verifiable semantic descriptions. Using digital twins of V1 and V4, we develop a closed-loop framework that translates each neuron's high- and low-activating images into dense captions, generates a semantic hypothesis and synthesized images, and verifies the hypothesis in silico. Descriptions range from oriented edges and spatial frequency in V1 to conjunctions of form, color, and texture in V4. In V4, images generated from activating and suppressing hypotheses drove 96.1% of neurons above the 95th and 97.6% below the 5th percentile of natural-image responses, respectively (vs. ~10% for random images); V1 activation results matched V4, while V1 suppression was less describable in language. Representational similarity analysis reveals partial alignment between neural activity, vision embeddings, and language embeddings, with vision most aligned to neural activity; alignment lost in the text bottleneck is recovered when hypotheses are rendered back into images, showing that linguistic compression is lossy yet semantically faithful. Together, these results show that combining generative models with neural digital twins enables interpretable, testable descriptions of neural function at scale, toward agentic scientific discovery.

Video saliency models typically apply a single fixation strategy across crowd scenes, despite systematic changes in attention with crowd density. Sparse scenes encourage tracking individuals, whereas dense scenes shift attention toward collective motion and scene-level landmarks. We introduce DensFiLM, a density-conditioned video saliency model that inserts a lightweight Feature-wise Linear Modulation layer at the bottleneck of a Video Swin Transformer. A learned density embedding produces channel-wise scale and shift parameters, allowing the decoder to reconstruct saliency from features selected for each density regime. The module adds only ~100K parameters and can use either CrowdFix density labels or the model's own density prediction. On CrowdFix, DensFiLM achieves mean NSS 1.434 and CC 0.517 over four seeds, improving over ACLNet by 14.7% and 14.9%, respectively, while predicted-density conditioning matches oracle-label performance. Ablations show that explicit RAFT optical flow and larger temporal and social-force extensions provide no further improvement in this setting. In a centre-prior-subtraction diagnostic, density conditioning yields an NSS gain of 0.462 over the unconditioned backbone, compared with 0.124 under standard evaluation. These results show that lightweight bottleneck conditioning provides a more effective inductive bias than increasing model capacity for crowd-video saliency. Our code is available at https://github.com/aniskhan25/crowdfix-saliency.

We present SAM4EM, a novel approach for 3D segmentation of complex neural structures in electron microscopy (EM) data by leveraging the Segment Anything Model (SAM) alongside advanced fine-tuning strategies. Our contributions include the development of a prompt-free adapter for SAM using two stage mask decoding to automatically generate prompt embeddings, a dual-stage fine-tuning method based on Low-Rank Adaptation (LoRA) for enhancing segmentation with limited annotated data, and a 3D memory attention mechanism to ensure segmentation consistency across 3D stacks. We further release a unique benchmark dataset for the segmentation of astrocytic processes and synapses. We evaluated our method on challenging neuroscience segmentation benchmarks, specifically targeting mitochondria, glia, and synapses, with significant accuracy improvements over state-of-the-art (SOTA) methods, including recent SAM-based adapters developed for the medical domain and other vision transformer-based approaches. Experimental results indicate that our approach outperforms existing solutions in the segmentation of complex processes like glia and post-synaptic densities. Our code and models are available at https://github.com/Uzshah/SAM4EM.

The whole-brain connectome of a fruit fly comprises over 130K neurons connected with a probability of merely 0.02%, yet achieves an average shortest path of only 4.4 hops. Despite being highly structured at the circuit level, the network's long-range connections are broadly distributed across brain regions, functioning as stochastic shortcuts that enable efficient global communication. Inspired by this observation, we propose Stochastic Attention (SA), a drop-in enhancement for sliding-window attention (SWA) that applies a random permutation to the token sequence before windowed attention and restores the original order afterward. This transforms the fixed local window into a stochastic global one within the same O(nw) per-layer budget. Through depth, independently sampled permutations yield exponentially growing receptive fields, achieving full sequence coverage in O(log_w n) layers versus O(n/w) for SWA. We validate SA in two settings: pre-training language models from scratch, where a gated SA + SWA combination achieves the best average zero-shot accuracy, and training-free inference on Qwen3-8B and Qwen3-30B-A3B, where SA consistently outperforms SWA and matches or exceeds Mixture of Block Attention at comparable compute budgets. These results suggest that connectome-inspired stochastic routing is a practical primitive for improving the expressivity of efficient attention, complementary to existing linear and sparse approaches.

Some neurons in deep networks specialize in recognizing highly specific perceptual, structural, or semantic features of inputs. In computer vision, techniques exist for identifying neurons that respond to individual concept categories like colors, textures, and object classes. But these techniques are limited in scope, labeling only a small subset of neurons and behaviors in any network. Is a richer characterization of neuron-level computation possible? We introduce a procedure (called MILAN, for mutual-information-guided linguistic annotation of neurons) that automatically labels neurons with open-ended, compositional, natural language descriptions. Given a neuron, MILAN generates a description by searching for a natural language string that maximizes pointwise mutual information with the image regions in which the neuron is active. MILAN produces fine-grained descriptions that capture categorical, relational, and logical structure in learned features. These descriptions obtain high agreement with human-generated feature descriptions across a diverse set of model architectures and tasks, and can aid in understanding and controlling learned models. We highlight three applications of natural language neuron descriptions. First, we use MILAN for analysis, characterizing the distribution and importance of neurons selective for attribute, category, and relational information in vision models. Second, we use MILAN for auditing, surfacing neurons sensitive to human faces in datasets designed to obscure them. Finally, we use MILAN for editing, improving robustness in an image classifier by deleting neurons sensitive to text features spuriously correlated with class labels.

Large Vision-Language Models (LVLMs) have recently demonstrated strong multimodal understanding, yet their fine-grained visual perception is often constrained by low input resolutions. A common remedy is to partition high-resolution images into multiple sub-images for separate encoding, but this approach drastically inflates the number of visual tokens and introduces prohibitive inference overhead. To overcome this challenge, we propose Pyramid Token Pruning (PTP), a training-free strategy that hierarchically integrates bottom-up visual saliency at both region and token levels with top-down instruction-guided relevance. Inspired by human visual cognition, PTP selectively preserves more tokens from salient regions while further emphasizing those most relevant to task instructions. Extensive experiments on 13 diverse benchmarks show that PTP substantially reduces computational cost, memory usage, and inference latency, with negligible performance degradation.

Effectively representing medical images, especially retinal images, presents a considerable challenge due to variations in appearance, size, and contextual information of pathological signs called lesions. Precise discrimination of these lesions is crucial for diagnosing vision-threatening issues such as diabetic retinopathy. While visual attention-based neural networks have been introduced to learn spatial context and channel correlations from retinal images, they often fall short in capturing localized lesion context. Addressing this limitation, we propose a novel attention mechanism called Guided Context Gating, an unique approach that integrates Context Formulation, Channel Correlation, and Guided Gating to learn global context, spatial correlations, and localized lesion context. Our qualitative evaluation against existing attention mechanisms emphasize the superiority of Guided Context Gating in terms of explainability. Notably, experiments on the Zenodo-DR-7 dataset reveal a substantial 2.63% accuracy boost over advanced attention mechanisms & an impressive 6.53% improvement over the state-of-the-art Vision Transformer for assessing the severity grade of retinopathy, even with imbalanced and limited training samples for each class.

Large language models (LLMs) frequently generate hallucinations -- plausible but factually incorrect outputs -- undermining their reliability. While prior work has examined hallucinations from macroscopic perspectives such as training data and objectives, the underlying neuron-level mechanisms remain largely unexplored. In this paper, we conduct a systematic investigation into hallucination-associated neurons (H-Neurons) in LLMs from three perspectives: identification, behavioral impact, and origins. Regarding their identification, we demonstrate that a remarkably sparse subset of neurons (less than 0.1% of total neurons) can reliably predict hallucination occurrences, with strong generalization across diverse scenarios. In terms of behavioral impact, controlled interventions reveal that these neurons are causally linked to over-compliance behaviors. Concerning their origins, we trace these neurons back to the pre-trained base models and find that these neurons remain predictive for hallucination detection, indicating they emerge during pre-training. Our findings bridge macroscopic behavioral patterns with microscopic neural mechanisms, offering insights for developing more reliable LLMs.

Adversarial examples are often cited by neuroscientists and machine learning researchers as an example of how computational models diverge from biological sensory systems. Recent work has proposed adding biologically-inspired components to visual neural networks as a way to improve their adversarial robustness. One surprisingly effective component for reducing adversarial vulnerability is response stochasticity, like that exhibited by biological neurons. Here, using recently developed geometrical techniques from computational neuroscience, we investigate how adversarial perturbations influence the internal representations of standard, adversarially trained, and biologically-inspired stochastic networks. We find distinct geometric signatures for each type of network, revealing different mechanisms for achieving robust representations. Next, we generalize these results to the auditory domain, showing that neural stochasticity also makes auditory models more robust to adversarial perturbations. Geometric analysis of the stochastic networks reveals overlap between representations of clean and adversarially perturbed stimuli, and quantitatively demonstrates that competing geometric effects of stochasticity mediate a tradeoff between adversarial and clean performance. Our results shed light on the strategies of robust perception utilized by adversarially trained and stochastic networks, and help explain how stochasticity may be beneficial to machine and biological computation.

Backpropagation algorithm has driven the remarkable success of deep neural networks, but its lack of biological plausibility and high computational costs have motivated the ongoing search for alternative training methods. Hebbian learning has attracted considerable interest as a biologically plausible alternative to backpropagation. Nevertheless, its exclusive reliance on local information, without consideration of global task objectives, fundamentally limits its scalability. Inspired by the biological synergy between neuromodulators and local plasticity, we introduce a novel model-agnostic Global-guided Hebbian Learning (GHL) framework, which seamlessly integrates local and global information to scale up across diverse networks and tasks. In specific, the local component employs Oja's rule with competitive learning to ensure stable and effective local updates. Meanwhile, the global component introduces a sign-based signal that guides the direction of local Hebbian plasticity updates. Extensive experiments demonstrate that our method consistently outperforms existing Hebbian approaches. Notably, on large-scale network and complex datasets like ImageNet, our framework achieves the competitive results and significantly narrows the gap with standard backpropagation.

Cortical visual prostheses aim to restore sight by electrically stimulating neurons in early visual cortex (V1). With the emergence of high-density and flexible neural interfaces, electrode placement within three-dimensional cortex has become a critical surgical planning problem. Existing strategies emphasize visual field coverage and anatomical heuristics but do not directly optimize predicted perceptual outcomes under safety constraints. We present a percept-aware framework for surgical planning of cortical visual prostheses that formulates electrode placement as a constrained optimization problem in anatomical space. Electrode coordinates are treated as learnable parameters and optimized end-to-end using a differentiable forward model of prosthetic vision. The objective minimizes task-level perceptual error while incorporating vascular avoidance and gray matter feasibility constraints. Evaluated on simulated reading and natural image tasks using realistic folded cortical geometry (FreeSurfer fsaverage), percept-aware optimization consistently improves reconstruction fidelity relative to coverage-based placement strategies. Importantly, vascular safety constraints eliminate margin violations while preserving perceptual performance. The framework further enables co-optimization of multi-electrode thread configurations under fixed insertion budgets. These results demonstrate how differentiable percept models can inform anatomically grounded, safety-aware computer-assisted planning for cortical neural interfaces and provide a foundation for optimizing next-generation visual prostheses.

Efficiently exploiting multi-modal inputs for accurate RGB-D saliency detection is a topic of high interest. Most existing works leverage cross-modal interactions to fuse the two streams of RGB-D for intermediate features' enhancement. In this process, a practical aspect of the low quality of the available depths has not been fully considered yet. In this work, we aim for RGB-D saliency detection that is robust to the low-quality depths which primarily appear in two forms: inaccuracy due to noise and the misalignment to RGB. To this end, we propose a robust RGB-D fusion method that benefits from (1) layer-wise, and (2) trident spatial, attention mechanisms. On the one hand, layer-wise attention (LWA) learns the trade-off between early and late fusion of RGB and depth features, depending upon the depth accuracy. On the other hand, trident spatial attention (TSA) aggregates the features from a wider spatial context to address the depth misalignment problem. The proposed LWA and TSA mechanisms allow us to efficiently exploit the multi-modal inputs for saliency detection while being robust against low-quality depths. Our experiments on five benchmark datasets demonstrate that the proposed fusion method performs consistently better than the state-of-the-art fusion alternatives.

Transformer architectures have revolutionized artificial intelligence (AI) through their attention mechanisms, yet the computational principles underlying their success remain opaque. We present a novel theoretical framework that reinterprets the core computation of attention as Pavlovian conditioning. Our model finds a direct mathematical analogue in linear attention, which simplifies the analysis of the underlying associative process. We demonstrate that attention's queries, keys, and values can be mapped to the three elements of classical conditioning: test stimuli that probe associations, conditional stimuli (CS) that serve as retrieval cues, and unconditional stimuli (US) that contain response information. Through this lens, we suggest that each attention operation constructs a transient associative memory via a Hebbian rule, where CS-US pairs form dynamic associations that test stimuli can later retrieve. Our framework yields several theoretical insights grounded in this linearized model: (1) a capacity theorem showing that attention heads can store O(d_k) associations before interference degrades retrieval; (2) an error propagation analysis revealing fundamental architectural trade-offs of balancing model depth, width, and head redundancy to maintain reliability; and (3) an understanding of how biologically plausible learning rules could enhance transformer architectures. By establishing this deep connection, we suggest that the success of modern AI may stem not from architectural novelty alone, but from implementing computational principles that biology optimized over millions of years of evolution.

Explainable Artificial Intelligence (XAI) techniques, such as Gradient-weighted Class Activation Mapping (Grad-CAM), have become indispensable for visualizing the reasoning process of deep neural networks in medical image analysis. Despite their popularity, the faithfulness and reliability of these heatmap-based explanations remain under scrutiny. This study critically investigates whether Grad-CAM truly represents the internal decision-making of deep models trained for lung cancer image classification. Using the publicly available IQ-OTH/NCCD dataset, we evaluate five representative architectures: ResNet-50, ResNet-101, DenseNet-161, EfficientNet-B0, and ViT-Base-Patch16-224, to explore model-dependent variations in Grad-CAM interpretability. We introduce a quantitative evaluation framework that combines localization accuracy, perturbation-based faithfulness, and explanation consistency to assess Grad-CAM reliability across architectures. Experimental findings reveal that while Grad-CAM effectively highlights salient tumor regions in most convolutional networks, its interpretive fidelity significantly degrades for Vision Transformer models due to non-local attention behavior. Furthermore, cross-model comparisons indicate substantial variability in saliency localization, implying that Grad-CAM explanations may not always correspond to the true diagnostic evidence used by the networks. This work exposes critical limitations of current saliency-based XAI approaches in medical imaging and emphasizes the need for model-aware interpretability methods that are both computationally sound and clinically meaningful. Our findings aim to inspire a more cautious and rigorous adoption of visual explanation tools in medical AI, urging the community to rethink what it truly means to "trust" a model's explanation.

We study a fully connected Hopfield-type associative memory network with online activity-dependent synaptic plasticity, where neural states and synaptic couplings coevolve during retrieval. Using the generating-functional formalism, we derive a dynamical mean-field theory (DMFT) in the large-system limit with extensively many stored random patterns, and show that the many-body dynamics reduces to an effective single-site stochastic process with colored Gaussian crosstalk noise and delayed feedback terms. Numerical solutions of the DMFT equations agree well with direct simulations. We find that moderate plasticity enlarges the basin of attraction and increases the maximum retrievable memory load by generating a positive delayed feedback that stabilizes retrieval against crosstalk noise. However, excessively strong plasticity causes the network to imprint the imperfect initial cue itself, leading to spurious attractors and degraded retrieval performance. Consequently, an optimal plasticity strength emerges from the trade-off between memory stabilization and premature cue imprinting. These results extend the DMFT description of associative memory to networks with coevolving neural and synaptic dynamics.

Understanding human visual attention on a scene over time has applications in domains such as interface design and inferring cognitive states. Modeling visual scanpaths has historically relied on specialized architectures with hand-crafted priors. While these architectures can model fixation sequences, their rigid structural biases restrict easy extendability and flexible conditioning. For instance, integrating task-specific instructions or adapting to distinct viewer identities requires custom, disjoint architectural additions. We frame scanpath prediction purely as a discrete sequence modeling task. By mapping coordinates into a text vocabulary, we leverage the pretrained representations of Vision-Language Models. This framing absorbs diverse factors of variation: simple prompting allows for global conditioning, such as providing viewer identities to capture personalized biases, or task-specific objectives like visual search. The framework can also integrate per-fixation attributes, such as individual fixation durations, alongside spatial locations. The autoregressive alignment enables the scalable, exact computation of per-fixation log-likelihoods, directly equivalent to the commonly used Information Gain (IG) metric. Our model, DeepGaze3.5-VL, establishes a new state-of-the-art across multiple datasets, achieving 2.18 bits of IG on MIT1003, a 46% improvement over DeepGaze III. This advantage persists even when baselines use identical high-capacity vision encoders. Beyond predictive performance, our generative framework serves as a powerful computational tool for direct behavioral interventions, allowing for controlled in-silico simulations that would be experimentally difficult or impossible to conduct in vivo. We demonstrate this ability by performing controlled interventions on the durations of pre-saccadic fixations, recovering known oculomotor phenomena purely from data.

We interpret the function of individual neurons in CLIP by automatically describing them using text. Analyzing the direct effects (i.e. the flow from a neuron through the residual stream to the output) or the indirect effects (overall contribution) fails to capture the neurons' function in CLIP. Therefore, we present the "second-order lens", analyzing the effect flowing from a neuron through the later attention heads, directly to the output. We find that these effects are highly selective: for each neuron, the effect is significant for <2% of the images. Moreover, each effect can be approximated by a single direction in the text-image space of CLIP. We describe neurons by decomposing these directions into sparse sets of text representations. The sets reveal polysemantic behavior - each neuron corresponds to multiple, often unrelated, concepts (e.g. ships and cars). Exploiting this neuron polysemy, we mass-produce "semantic" adversarial examples by generating images with concepts spuriously correlated to the incorrect class. Additionally, we use the second-order effects for zero-shot segmentation and attribute discovery in images. Our results indicate that a scalable understanding of neurons can be used for model deception and for introducing new model capabilities.

We present a simple mathematical model for the mammalian low visual pathway, taking into account its key elements: retina, lateral geniculate nucleus (LGN), primary visual cortex (V1). The analogies between the cortical level of the visual system and the structure of popular CNNs, used in image classification tasks, suggests the introduction of an additional preliminary convolutional module inspired to precortical neuronal circuits to improve robustness with respect to global light intensity and contrast variations in the input images. We validate our hypothesis on the popular databases MNIST, FashionMNIST and SVHN, obtaining significantly more robust CNNs with respect to these variations, once such extra module is added.

Partially inspired by features of computation in visual cortex, deep neural networks compute hierarchical representations of their inputs. While these networks have been highly successful in machine learning, it remains unclear to what extent they can aid our understanding of cortical function. Several groups have developed metrics that provide a quantitative comparison between representations computed by networks and representations measured in cortex. At the same time, neuroscience is well into an unprecedented phase of large-scale data collection, as evidenced by projects such as the Allen Brain Observatory. Despite the magnitude of these efforts, in a given experiment only a fraction of units are recorded, limiting the information available about the cortical representation. Moreover, only a finite number of stimuli can be shown to an animal over the course of a realistic experiment. These limitations raise the question of how and whether metrics that compare representations of deep networks are meaningful on these datasets. Here, we empirically quantify the capabilities and limitations of these metrics due to limited image presentations and neuron samples. We find that the comparison procedure is robust to different choices of stimuli set and the level of subsampling that one might expect in a large-scale brain survey with thousands of neurons. Using these results, we compare the representations measured in the Allen Brain Observatory in response to natural image presentations to deep neural network. We show that the visual cortical areas are relatively high order representations (in that they map to deeper layers of convolutional neural networks). Furthermore, we see evidence of a broad, more parallel organization rather than a sequential hierarchy, with the primary area VISp(V1) being lower order relative to the other areas.

Spiking neural networks (SNNs) offer both compelling potential advantages, including energy efficiency and low latencies and challenges including the non-differentiable nature of event spikes. Much of the initial research in this area has converted deep neural networks to equivalent SNNs, but this conversion approach potentially negates some of the advantages of SNN-based approaches developed from scratch. One promising area for high-performance SNNs is template matching and image recognition. This research introduces the first high-performance SNN for the Visual Place Recognition (VPR) task: given a query image, the SNN has to find the closest match out of a list of reference images. At the core of this new system is a novel assignment scheme that implements a form of ambiguity-informed salience, by up-weighting single-place-encoding neurons and down-weighting "ambiguous" neurons that respond to multiple different reference places. In a range of experiments on the challenging Nordland, Oxford RobotCar, SPEDTest, Synthia, and St Lucia datasets, we show that our SNN achieves comparable VPR performance to state-of-the-art and classical techniques, and degrades gracefully in performance with an increasing number of reference places. Our results provide a significant milestone towards SNNs that can provide robust, energy-efficient, and low latency robot localization.

The truthfulness of existing explanation methods in authentically elucidating the underlying model's decision-making process has been questioned. Existing methods have deviated from faithfully representing the model, thus susceptible to adversarial attacks. To address this, we propose a novel eXplainable AI (XAI) method called SRD (Sharing Ratio Decomposition), which sincerely reflects the model's inference process, resulting in significantly enhanced robustness in our explanations. Different from the conventional emphasis on the neuronal level, we adopt a vector perspective to consider the intricate nonlinear interactions between filters. We also introduce an interesting observation termed Activation-Pattern-Only Prediction (APOP), letting us emphasize the importance of inactive neurons and redefine relevance encapsulating all relevant information including both active and inactive neurons. Our method, SRD, allows for the recursive decomposition of a Pointwise Feature Vector (PFV), providing a high-resolution Effective Receptive Field (ERF) at any layer.

Modeling invasive neural spike data is fundamental to advancing high-performance brain-computer interfaces (BCIs). However, existing approaches face critical challenges, including limited-scale heterogeneous data, cross-domain distribution shift, and the intrinsic spatiotemporal complexity of invasive neural signals. In this work, we propose UniBCI, a unified pretrained model for invasive Brain-Computer Interfaces. The model integrates three key components: (1) a context-conditioned spatio-temporal tokenization (CST) scheme that embeds neural signals together with metadata into a shared representation space; (2) a hierarchical Interval-Area Attention (IAA) mechanism that captures patterns of spike dynamics in slots via linear attention and locality dependencies via sliding-window attention; and (3) a scalable self-supervised masked signals reconstruction objective for learning generalizable neural representations from large-scale unlabeled data. We construct a pretraining corpus spanning multiple species, subjects, brain regions, and behavioral experiment paradigms. These heterogeneous recordings are standardize via our proposed unified normalization and tokenization. Comprehensive experiments demonstrate that UniBCI achieves SOTA performance across diverse downstream tasks while improving generalization. Moreover, the model achieves a strong balance between accuracy and efficiency, with fewer trainable parameters and lower inference latency. These results suggest that UniBCI provides a practical step toward general-purpose neural foundation models, enabling robust, scalable, and transferable representation learning for invasive neural data. The code for this paper is available at: https://anonymous.4open.science/r/UniBCI-C805.

Training-free image editing with large diffusion models has become practical, yet faithfully performing complex non-rigid edits (e.g., pose or shape changes) remains highly challenging. We identify a key underlying cause: attention collapse in existing attention sharing mechanisms, where either positional embeddings or semantic features dominate visual content retrieval, leading to over-editing or under-editing. To address this issue, we introduce SynPS, a method that Synergistically leverages Positional embeddings and Semantic information for faithful non-rigid image editing. We first propose an editing measurement that quantifies the required editing magnitude at each denoising step. Based on this measurement, we design an attention synergy pipeline that dynamically modulates the influence of positional embeddings, enabling SynPS to balance semantic modifications and fidelity preservation. By adaptively integrating positional and semantic cues, SynPS effectively avoids both over- and under-editing. Extensive experiments on public and newly curated benchmarks demonstrate the superior performance and faithfulness of our approach.

Networks capture our intuition about relationships in the world. They describe the friendships between Facebook users, interactions in financial markets, and synapses connecting neurons in the brain. These networks are richly structured with cliques of friends, sectors of stocks, and a smorgasbord of cell types that govern how neurons connect. Some networks, like social network friendships, can be directly observed, but in many cases we only have an indirect view of the network through the actions of its constituents and an understanding of how the network mediates that activity. In this work, we focus on the problem of latent network discovery in the case where the observable activity takes the form of a mutually-excitatory point process known as a Hawkes process. We build on previous work that has taken a Bayesian approach to this problem, specifying prior distributions over the latent network structure and a likelihood of observed activity given this network. We extend this work by proposing a discrete-time formulation and developing a computationally efficient stochastic variational inference (SVI) algorithm that allows us to scale the approach to long sequences of observations. We demonstrate our algorithm on the calcium imaging data used in the Chalearn neural connectomics challenge.

Models of neural responses to stimuli with complex spatiotemporal correlation structure often assume that neurons are only selective for a small number of linear projections of a potentially high-dimensional input. Here we explore recent modeling approaches where the neural response depends on the quadratic form of the input rather than on its linear projection, that is, the neuron is sensitive to the local covariance structure of the signal preceding the spike. To infer this quadratic dependence in the presence of arbitrary (e.g. naturalistic) stimulus distribution, we review several inference methods, focussing in particular on two information-theory-based approaches (maximization of stimulus energy or of noise entropy) and a likelihood-based approach (Bayesian spike-triggered covariance, extensions of generalized linear models). We analyze the formal connection between the likelihood-based and information-based approaches to show how they lead to consistent inference. We demonstrate the practical feasibility of these procedures by using model neurons responding to a flickering variance stimulus.

In this work, we study the Efficient Multimodal Large Language Model. Redundant vision tokens consume a significant amount of computational memory and resources. Therefore, many previous works compress them in the Vision Projector to reduce the number of vision tokens. However, simply compressing in the Vision Projector can lead to the loss of visual information, especially for tasks that rely on fine-grained spatial relationships, such as OCR and Chart \& Table Understanding. To address this problem, we propose Vision Remember, which is inserted between the LLM decoder layers to allow vision tokens to re-memorize vision features. Specifically, we retain multi-level vision features and resample them with the vision tokens that have interacted with the text token. During the resampling process, each vision token only attends to a local region in vision features, which is referred to as saliency-enhancing local attention. Saliency-enhancing local attention not only improves computational efficiency but also captures more fine-grained contextual information and spatial relationships within the region. Comprehensive experiments on multiple visual understanding benchmarks validate the effectiveness of our method when combined with various Efficient Vision Projectors, showing performance gains without sacrificing efficiency. Based on Vision Remember, LLaVA-VR with only 2B parameters is also superior to previous representative MLLMs such as Tokenpacker-HD-7B and DeepSeek-VL-7B.

Decoding approaches are widely used in neuroscience and machine learning to compare stimulus representations across neural systems, such as different brain regions, organisms, and deep learning models. Popular methods include decoding (perceptual) manifolds and alignment metrics such as Representational Similarity Analysis (RSA) and Dynamic Similarity Analysis (DSA), where similarity in decoding representations is interpreted as evidence for similar computation. This paper demonstrates a fundamental weakness behind this approach: it is misleading to assume that representational geometry is representative of a neuronal population as a whole, when such representations may actually be shaped by a very small subset of neurons. We show that the complementary encoding paradigm addresses this issue directly: it characterizes how neurons are organized globally in terms of their responses to a set of data, providing insight into how the decoding representation is implemented by neurons within a population. We demonstrate across experiments in biological systems and deep learning models that (i) surprisingly, similar decoding behavior and high representational alignment can arise from small, non-representative subpopulations of neurons; and critically, (ii) alignment metrics are insensitive to encoding manifold topology (how function is distributed across neurons), despite this being a key signature of differentiation across biological systems. A controlled MNIST experiment provides causal evidence: decoding metrics remain unchanged even when encoding topology is causally manipulated via the training loss. Overall, similarity in decoding behavior, as measured by classic alignment metrics, does not imply similarity in function or computation, motivating the use of encoding manifolds as a complementary tool for comparing neural systems.

With the growing accessibility and wide adoption of large language models, concerns about their safety and alignment with human values have become paramount. In this paper, we identify a concerning phenomenon: Reasoning-Induced Misalignment (RIM), in which misalignment emerges when reasoning capabilities strengthened-particularly when specific types of reasoning patterns are introduced during inference or training. Beyond reporting this vulnerability, we provide the first mechanistic account of its origins. Through representation analysis, we discover that specific attention heads facilitate refusal by reducing their attention to CoT tokens, a mechanism that modulates the model's rationalization process during inference. During training, we find significantly higher activation entanglement between reasoning and safety in safety-critical neurons than in control neurons, particularly after fine-tuning with those identified reasoning patterns. This entanglement strongly correlates with catastrophic forgetting, providing a neuron-level explanation for RIM.

A neuroscience method to understanding the brain is to find and study the preferred stimuli that highly activate an individual cell or groups of cells. Recent advances in machine learning enable a family of methods to synthesize preferred stimuli that cause a neuron in an artificial or biological brain to fire strongly. Those methods are known as Activation Maximization (AM) or Feature Visualization via Optimization. In this chapter, we (1) review existing AM techniques in the literature; (2) discuss a probabilistic interpretation for AM; and (3) review the applications of AM in debugging and explaining networks.

Recent self-supervised learning (SSL) models trained on human-like egocentric visual inputs substantially underperform on image recognition tasks compared to humans. These models train on raw, uniform visual inputs collected from head-mounted cameras. This is different from humans, as the anatomical structure of the retina and visual cortex relatively amplifies the central visual information, i.e. around humans' gaze location. This selective amplification in humans likely aids in forming object-centered visual representations. Here, we investigate whether focusing on central visual information boosts egocentric visual object learning. We simulate 5-months of egocentric visual experience using the large-scale Ego4D dataset and generate gaze locations with a human gaze prediction model. To account for the importance of central vision in humans, we crop the visual area around the gaze location. Finally, we train a time-based SSL model on these modified inputs. Our experiments demonstrate that focusing on central vision leads to better object-centered representations. Our analysis shows that the SSL model leverages the temporal dynamics of the gaze movements to build stronger visual representations. Overall, our work marks a significant step toward bio-inspired learning of visual representations.

Representation learning constitutes a pivotal cornerstone in contemporary deep learning paradigms, offering a conduit to elucidate distinctive features within the latent space and interpret the deep models. Nevertheless, the inherent complexity of anatomical patterns and the random nature of lesion distribution in medical image segmentation pose significant challenges to the disentanglement of representations and the understanding of salient features. Methods guided by the maximization of mutual information, particularly within the framework of contrastive learning, have demonstrated remarkable success and superiority in decoupling densely intertwined representations. However, the effectiveness of contrastive learning highly depends on the quality of the positive and negative sample pairs, i.e. the unselected average mutual information among multi-views would obstruct the learning strategy so the selection of the views is vital. In this work, we introduce a novel approach predicated on representation distance-based mutual information (MI) maximization for measuring the significance of different views, aiming at conducting more efficient contrastive learning and representation disentanglement. Additionally, we introduce an MI re-ranking strategy for representation selection, benefiting both the continuous MI estimating and representation significance distance measuring. Specifically, we harness multi-view representations extracted from the frequency domain, re-evaluating their significance based on mutual information across varying frequencies, thereby facilitating a multifaceted contrastive learning approach to bolster semantic comprehension. The statistical results under the five metrics demonstrate that our proposed framework proficiently constrains the MI maximization-driven representation selection and steers the multi-view contrastive learning process.

We develop a method for comparing hierarchical image representations in terms of their ability to explain perceptual sensitivity in humans. Specifically, we utilize Fisher information to establish a model-derived prediction of sensitivity to local perturbations of an image. For a given image, we compute the eigenvectors of the Fisher information matrix with largest and smallest eigenvalues, corresponding to the model-predicted most- and least-noticeable image distortions, respectively. For human subjects, we then measure the amount of each distortion that can be reliably detected when added to the image. We use this method to test the ability of a variety of representations to mimic human perceptual sensitivity. We find that the early layers of VGG16, a deep neural network optimized for object recognition, provide a better match to human perception than later layers, and a better match than a 4-stage convolutional neural network (CNN) trained on a database of human ratings of distorted image quality. On the other hand, we find that simple models of early visual processing, incorporating one or more stages of local gain control, trained on the same database of distortion ratings, provide substantially better predictions of human sensitivity than either the CNN, or any combination of layers of VGG16.

In the pursuit to understand the intricacies of human brain's visual processing, reconstructing dynamic visual experiences from brain activities emerges as a challenging yet fascinating endeavor. While recent advancements have achieved success in reconstructing static images from non-invasive brain recordings, the domain of translating continuous brain activities into video format remains underexplored. In this work, we introduce NeuroCine, a novel dual-phase framework to targeting the inherent challenges of decoding fMRI data, such as noises, spatial redundancy and temporal lags. This framework proposes spatial masking and temporal interpolation-based augmentation for contrastive learning fMRI representations and a diffusion model enhanced by dependent prior noise for video generation. Tested on a publicly available fMRI dataset, our method shows promising results, outperforming the previous state-of-the-art models by a notable margin of {20.97%}, {31.00%} and {12.30%} respectively on decoding the brain activities of three subjects in the fMRI dataset, as measured by SSIM. Additionally, our attention analysis suggests that the model aligns with existing brain structures and functions, indicating its biological plausibility and interpretability.

Deep saliency prediction algorithms complement the object recognition features, they typically rely on additional information, such as scene context, semantic relationships, gaze direction, and object dissimilarity. However, none of these models consider the temporal nature of gaze shifts during image observation. We introduce a novel saliency prediction model that learns to output saliency maps in sequential time intervals by exploiting human temporal attention patterns. Our approach locally modulates the saliency predictions by combining the learned temporal maps. Our experiments show that our method outperforms the state-of-the-art models, including a multi-duration saliency model, on the SALICON benchmark. Our code will be publicly available on GitHub.

High-resolution brain imaging can now capture not just synapse locations but their molecular composition, with the cost of such mapping falling exponentially. Yet such ultrastructural data has so far told us little about local neuronal physiology - specifically, the parameters (e.g., synaptic efficacies, local conductances) that govern neural dynamics. We propose to translate molecularly annotated ultrastructure into physiology, introducing the concept of an ultrastructure-to-dynamics compiler: a learned mapping from molecularly annotated ultrastructure to simulator-ready, uncertainty-aware physiological parameters. The requirement is paired training data, with jointly acquired ultrastructure from imaging, and dynamical responses to perturbations from physiological experiments. With this data we can train models that predict local physiology directly from structure. Such a compiler would support biophysical simulations by turning anatomical maps into models of circuit dynamics, shifting structure-to-function from a descriptive program to a predictive one and opening routes to understanding neural computation and forecasting intervention effects.

The goal of this work is to characterize the representational impact that foveation operations have for machine vision systems, inspired by the foveated human visual system, which has higher acuity at the center of gaze and texture-like encoding in the periphery. To do so, we introduce models consisting of a first-stage fixed image transform followed by a second-stage learnable convolutional neural network, and we varied the first stage component. The primary model has a foveated-textural input stage, which we compare to a model with foveated-blurred input and a model with spatially-uniform blurred input (both matched for perceptual compression), and a final reference model with minimal input-based compression. We find that: 1) the foveated-texture model shows similar scene classification accuracy as the reference model despite its compressed input, with greater i.i.d. generalization than the other models; 2) the foveated-texture model has greater sensitivity to high-spatial frequency information and greater robustness to occlusion, w.r.t the comparison models; 3) both the foveated systems, show a stronger center image-bias relative to the spatially-uniform systems even with a weight sharing constraint. Critically, these results are preserved over different classical CNN architectures throughout their learning dynamics. Altogether, this suggests that foveation with peripheral texture-based computations yields an efficient, distinct, and robust representational format of scene information, and provides symbiotic computational insight into the representational consequences that texture-based peripheral encoding may have for processing in the human visual system, while also potentially inspiring the next generation of computer vision models via spatially-adaptive computation. Code + Data available here: https://github.com/ArturoDeza/EmergentProperties

Growing evidence indicates that only a sparse subset from a pool of sensory neurons is active for the encoding of visual stimuli at any instant in time. Traditionally, to replicate such biological sparsity, generative models have been using the ell_1 norm as a penalty due to its convexity, which makes it amenable to fast and simple algorithmic solvers. In this work, we use biological vision as a test-bed and show that the soft thresholding operation associated to the use of the ell_1 norm is highly suboptimal compared to other functions suited to approximating ell_q with 0 leq q < 1 (including recently proposed Continuous Exact relaxations), both in terms of performance and in the production of features that are akin to signatures of the primary visual cortex. We show that ell_1 sparsity produces a denser code or employs a pool with more neurons, i.e. has a higher degree of overcompleteness, in order to maintain the same reconstruction error as the other methods considered. For all the penalty functions tested, a subset of the neurons develop orientation selectivity similarly to V1 neurons. When their code is sparse enough, the methods also develop receptive fields with varying functionalities, another signature of V1. Compared to other methods, soft thresholding achieves this level of sparsity at the expense of much degraded reconstruction performance, that more likely than not is not acceptable in biological vision. Our results indicate that V1 uses a sparsity inducing regularization that is closer to the ell_0 pseudo-norm rather than to the ell_1 norm.

The problem of visual metamerism is defined as finding a family of perceptually indistinguishable, yet physically different images. In this paper, we propose our NeuroFovea metamer model, a foveated generative model that is based on a mixture of peripheral representations and style transfer forward-pass algorithms. Our gradient-descent free model is parametrized by a foveated VGG19 encoder-decoder which allows us to encode images in high dimensional space and interpolate between the content and texture information with adaptive instance normalization anywhere in the visual field. Our contributions include: 1) A framework for computing metamers that resembles a noisy communication system via a foveated feed-forward encoder-decoder network -- We observe that metamerism arises as a byproduct of noisy perturbations that partially lie in the perceptual null space; 2) A perceptual optimization scheme as a solution to the hyperparametric nature of our metamer model that requires tuning of the image-texture tradeoff coefficients everywhere in the visual field which are a consequence of internal noise; 3) An ABX psychophysical evaluation of our metamers where we also find that the rate of growth of the receptive fields in our model match V1 for reference metamers and V2 between synthesized samples. Our model also renders metamers at roughly a second, presenting a times1000 speed-up compared to the previous work, which allows for tractable data-driven metamer experiments.

Understanding how the brain represents visual information is a fundamental challenge in neuroscience and artificial intelligence. While AI-driven decoding of neural data has provided insights into the human visual system, integrating multimodal neuroimaging signals, such as EEG, MEG, and fMRI, remains a critical hurdle due to their inherent spatiotemporal misalignment. Current approaches often analyze these modalities in isolation, limiting a holistic view of neural representation. In this study, we introduce BrainFLORA, a unified framework for integrating cross-modal neuroimaging data to construct a shared neural representation. Our approach leverages multimodal large language models (MLLMs) augmented with modality-specific adapters and task decoders, achieving state-of-the-art performance in joint-subject visual retrieval task and has the potential to extend multitasking. Combining neuroimaging analysis methods, we further reveal how visual concept representations align across neural modalities and with real world object perception. We demonstrate that the brain's structured visual concept representations exhibit an implicit mapping to physical-world stimuli, bridging neuroscience and machine learning from different modalities of neural imaging. Beyond methodological advancements, BrainFLORA offers novel implications for cognitive neuroscience and brain-computer interfaces (BCIs). Our code is available at https://github.com/ncclab-sustech/BrainFLORA.

Contextual memory integration remains a high challenge in the development of language models, particularly in tasks that require maintaining coherence over extended sequences. Traditional approaches, such as self-attention mechanisms and memory-augmented architectures, often prioritize short-term dependencies, leading to fragmentation and inconsistency in long-range contextual understanding. Inspired by principles of synaptic plasticity observed in biological neural systems, a novel mechanism, Synaptic Resonance, is introduced to dynamically reinforce relevant memory pathways during training and inference. Unlike static memory representations, this mechanism continuously adjusts synaptic weight matrices based on contextual relevance, allowing for improved information retention without excessive computational overhead. Evaluations conducted on an open-source language model demonstrate reductions in perplexity, enhancements in contextual coherence, and increased robustness against input noise, highlighting the effectiveness of reinforcement-driven memory modulation. Comparative analysis against baseline models further reveals that the proposed approach achieves higher memory retention efficiency while maintaining computational feasibility. The architectural modifications integrate seamlessly into existing transformer-based frameworks, ensuring stable convergence and efficient inference without sacrificing scalability. Applications benefiting from improved long-term contextual consistency, such as dialogue systems and document summarization, stand to gain from this approach. Empirical findings suggest that dynamically reinforced memory pathways offer a promising alternative to conventional memory mechanisms, addressing longstanding limitations in extended sequence modeling.

The brain is the perfect place to look for inspiration to develop more efficient neural networks. The inner workings of our synapses and neurons provide a glimpse at what the future of deep learning might look like. This paper serves as a tutorial and perspective showing how to apply the lessons learnt from several decades of research in deep learning, gradient descent, backpropagation and neuroscience to biologically plausible spiking neural neural networks. We also explore the delicate interplay between encoding data as spikes and the learning process; the challenges and solutions of applying gradient-based learning to spiking neural networks (SNNs); the subtle link between temporal backpropagation and spike timing dependent plasticity, and how deep learning might move towards biologically plausible online learning. Some ideas are well accepted and commonly used amongst the neuromorphic engineering community, while others are presented or justified for the first time here. The fields of deep learning and spiking neural networks evolve very rapidly. We endeavour to treat this document as a 'dynamic' manuscript that will continue to be updated as the common practices in training SNNs also change. A series of companion interactive tutorials complementary to this paper using our Python package, snnTorch, are also made available. See https://snntorch.readthedocs.io/en/latest/tutorials/index.html .

Medical image analysis continues to hold interesting challenges given the subtle characteristics of certain diseases and the significant overlap in appearance between diseases. In this work, we explore the concept of self-attention for tackling such subtleties in and between diseases. To this end, we introduce MEDUSA, a multi-scale encoder-decoder self-attention mechanism tailored for medical image analysis. While self-attention deep convolutional neural network architectures in existing literature center around the notion of multiple isolated lightweight attention mechanisms with limited individual capacities being incorporated at different points in the network architecture, MEDUSA takes a significant departure from this notion by possessing a single, unified self-attention mechanism with significantly higher capacity with multiple attention heads feeding into different scales in the network architecture. To the best of the authors' knowledge, this is the first "single body, multi-scale heads" realization of self-attention and enables explicit global context amongst selective attention at different levels of representational abstractions while still enabling differing local attention context at individual levels of abstractions. With MEDUSA, we obtain state-of-the-art performance on multiple challenging medical image analysis benchmarks including COVIDx, RSNA RICORD, and RSNA Pneumonia Challenge when compared to previous work. Our MEDUSA model is publicly available.

A key requirement for the development of effective learning representations is their evaluation and comparison to representations we know to be effective. In natural sensory domains, the community has viewed the brain as a source of inspiration and as an implicit benchmark for success. However, it has not been possible to directly test representational learning algorithms directly against the representations contained in neural systems. Here, we propose a new benchmark for visual representations on which we have directly tested the neural representation in multiple visual cortical areas in macaque (utilizing data from [Majaj et al., 2012]), and on which any computer vision algorithm that produces a feature space can be tested. The benchmark measures the effectiveness of the neural or machine representation by computing the classification loss on the ordered eigendecomposition of a kernel matrix [Montavon et al., 2011]. In our analysis we find that the neural representation in visual area IT is superior to visual area V4. In our analysis of representational learning algorithms, we find that three-layer models approach the representational performance of V4 and the algorithm in [Le et al., 2012] surpasses the performance of V4. Impressively, we find that a recent supervised algorithm [Krizhevsky et al., 2012] achieves performance comparable to that of IT for an intermediate level of image variation difficulty, and surpasses IT at a higher difficulty level. We believe this result represents a major milestone: it is the first learning algorithm we have found that exceeds our current estimate of IT representation performance. We hope that this benchmark will assist the community in matching the representational performance of visual cortex and will serve as an initial rallying point for further correspondence between representations derived in brains and machines.

Attention sinks are tokens, often the beginning-of-sequence (BOS) token, that receive disproportionately high attention despite limited semantic relevance. In this work, we identify a class of attention sinks, which we term secondary sinks, that differ fundamentally from the sinks studied in prior works, which we term primary sinks. While prior works have identified that tokens other than BOS can sometimes become sinks, they were found to exhibit properties analogous to the BOS token. Specifically, they emerge at the same layer, persist throughout the network and draw a large amount of attention mass. Whereas, we find the existence of secondary sinks that arise primarily in middle layers and can persist for a variable number of layers, and draw a smaller, but still significant, amount of attention mass. Through extensive experiments across 11 model families, we analyze where these secondary sinks appear, their properties, how they are formed, and their impact on the attention mechanism. Specifically, we show that: (1) these sinks are formed by specific middle-layer MLP modules; these MLPs map token representations to vectors that align with the direction of the primary sink of that layer. (2) The ell_2-norm of these vectors determines the sink score of the secondary sink, and also the number of layers it lasts for, thereby leading to different impacts on the attention mechanisms accordingly. (3) The primary sink weakens in middle layers, coinciding with the emergence of secondary sinks. We observe that in larger-scale models, the location and lifetime of the sinks, together referred to as sink levels, appear in a more deterministic and frequent manner. Specifically, we identify three sink levels in QwQ-32B and six levels in Qwen3-14B.

Salient segmentation aims to segment out attention-grabbing regions, a critical yet challenging task and the foundation of many high-level computer vision applications. It requires semantic-aware grouping of pixels into salient regions and benefits from the utilization of global multi-scale contexts to achieve good local reasoning. Previous works often address it as two-class segmentation problems utilizing complicated multi-step procedures including refinement networks and complex graphical models. We argue that semantic salient segmentation can instead be effectively resolved by reformulating it as a simple yet intuitive pixel-pair based connectivity prediction task. Following the intuition that salient objects can be naturally grouped via semantic-aware connectivity between neighboring pixels, we propose a pure Connectivity Net (ConnNet). ConnNet predicts connectivity probabilities of each pixel with its neighboring pixels by leveraging multi-level cascade contexts embedded in the image and long-range pixel relations. We investigate our approach on two tasks, namely salient object segmentation and salient instance-level segmentation, and illustrate that consistent improvements can be obtained by modeling these tasks as connectivity instead of binary segmentation tasks for a variety of network architectures. We achieve state-of-the-art performance, outperforming or being comparable to existing approaches while reducing inference time due to our less complex approach.

Every day, humans perceive objects and communicate these perceptions through various channels. In this paper, we present a computational model designed to track and simulate the perception of objects, as well as their representations as conveyed in communication. We delineate two fundamental components of our internal representation, termed "observed" and "seen", which we correlate with established concepts in computer vision, namely encoding and decoding. These components are integrated into semiotic networks, which simulate perceptual inference of object perception and human communication. Our model of object perception by a person allows us to define object perception by {\em a network}. We demonstrate this with an example of an image baseline classifier by constructing a new network that includes the baseline classifier and an additional layer. This layer produces the images "perceived" by the entire network, transforming it into a perceptualized image classifier. This facilitates visualization of the acquired network. Within our network, the image representations become more efficient for classification tasks when they are assembled and randomized. In our experiments, the perceptualized network outperformed the baseline classifier on MNIST training databases consisting of a restricted number of images. Our model is not limited to persons and can be applied to any system featuring a loop involving the processing from "internal" to "external" representations.

In deep learning, visualization techniques extract the salient patterns exploited by deep networks for image classification, focusing on single images; no effort has been spent in investigating whether these patterns are systematically related to precise semantic entities over multiple images belonging to a same class, thus failing to capture the very understanding of the image class the network has realized. This paper goes in this direction, presenting a visualization framework which produces a group of clusters or summaries, each one formed by crisp salient image regions focusing on a particular part that the network has exploited with high regularity to decide for a given class. The approach is based on a sparse optimization step providing sharp image saliency masks that are clustered together by means of a semantic flow similarity measure. The summaries communicate clearly what a network has exploited of a particular image class, and this is proved through automatic image tagging and with a user study. Beyond the deep network understanding, summaries are also useful for many quantitative reasons: their number is correlated with ability of a network to classify (more summaries, better performances), and they can be used to improve the classification accuracy of a network through summary-driven specializations.

Spiking neural networks (SNNs) possess energy-efficient potential due to event-based computation. However, supervised training of SNNs remains a challenge as spike activities are non-differentiable. Previous SNNs training methods can be generally categorized into two basic classes, i.e., backpropagation-like training methods and plasticity-based learning methods. The former methods are dependent on energy-inefficient real-valued computation and non-local transmission, as also required in artificial neural networks (ANNs), whereas the latter are either considered to be biologically implausible or exhibit poor performance. Hence, biologically plausible (bio-plausible) high-performance supervised learning (SL) methods for SNNs remain deficient. In this paper, we proposed a novel bio-plausible SNN model for SL based on the symmetric spike-timing dependent plasticity (sym-STDP) rule found in neuroscience. By combining the sym-STDP rule with bio-plausible synaptic scaling and intrinsic plasticity of the dynamic threshold, our SNN model implemented SL well and achieved good performance in the benchmark recognition task (MNIST dataset). To reveal the underlying mechanism of our SL model, we visualized both layer-based activities and synaptic weights using the t-distributed stochastic neighbor embedding (t-SNE) method after training and found that they were well clustered, thereby demonstrating excellent classification ability. Furthermore, to verify the robustness of our model, we trained it on another more realistic dataset (Fashion-MNIST), which also showed good performance. As the learning rules were bio-plausible and based purely on local spike events, our model could be easily applied to neuromorphic hardware for online training and may be helpful for understanding SL information processing at the synaptic level in biological neural systems.

The objective of this study is to investigate the application of various channel attention mechanisms within the domain of brain-computer interface (BCI) for motor imagery decoding. Channel attention mechanisms can be seen as a powerful evolution of spatial filters traditionally used for motor imagery decoding. This study systematically compares such mechanisms by integrating them into a lightweight architecture framework to evaluate their impact. We carefully construct a straightforward and lightweight baseline architecture designed to seamlessly integrate different channel attention mechanisms. This approach is contrary to previous works which only investigate one attention mechanism and usually build a very complex, sometimes nested architecture. Our framework allows us to evaluate and compare the impact of different attention mechanisms under the same circumstances. The easy integration of different channel attention mechanisms as well as the low computational complexity enables us to conduct a wide range of experiments on four datasets to thoroughly assess the effectiveness of the baseline model and the attention mechanisms. Our experiments demonstrate the strength and generalizability of our architecture framework as well as how channel attention mechanisms can improve the performance while maintaining the small memory footprint and low computational complexity of our baseline architecture. Our architecture emphasizes simplicity, offering easy integration of channel attention mechanisms, while maintaining a high degree of generalizability across datasets, making it a versatile and efficient solution for EEG motor imagery decoding within brain-computer interfaces.

Due to the capability of dynamic state space models (SSMs) in capturing long-range dependencies with linear-time computational complexity, Mamba has shown notable performance in NLP tasks. This has inspired the rapid development of Mamba-based vision models, resulting in promising results in visual recognition tasks. However, such models are not capable of distilling features across layers through feature aggregation, interaction, and selection. Moreover, existing cross-layer feature aggregation methods designed for CNNs or ViTs are not practical in Mamba-based models due to high computational costs. Therefore, this paper aims to introduce an efficient cross-layer feature aggregation mechanism for vision backbone networks. Inspired by the Retinal Ganglion Cells (RGCs) in the human visual system, we propose a new sparse cross-layer connection mechanism termed SparX to effectively improve cross-layer feature interaction and reuse. Specifically, we build two different types of network layers: ganglion layers and normal layers. The former has higher connectivity and complexity, enabling multi-layer feature aggregation and interaction in an input-dependent manner. In contrast, the latter has lower connectivity and complexity. By interleaving these two types of layers, we design a new family of vision backbone networks with sparsely cross-connected layers, achieving an excellent trade-off among model size, computational cost, memory cost, and accuracy in comparison to its counterparts. For instance, with fewer parameters, SparX-Mamba-T improves the top-1 accuracy of VMamba-T from 82.5\% to 83.5\%, while SparX-Swin-T achieves a 1.3\% increase in top-1 accuracy compared to Swin-T. Extensive experimental results demonstrate that our new connection mechanism possesses both superior performance and generalization capabilities on various vision tasks.

Vision-Language Models (VLMs) have recently demonstrated remarkable capabilities in comprehending complex visual content. However, the mechanisms underlying how VLMs process visual information remain largely unexplored. In this paper, we conduct a thorough empirical analysis, focusing on attention modules across layers. We reveal several key insights about how these models process visual data: (i) the internal representation of the query tokens (e.g., representations of "describe the image"), is utilized by VLMs to store global image information; we demonstrate that these models generate surprisingly descriptive responses solely from these tokens, without direct access to image tokens. (ii) Cross-modal information flow is predominantly influenced by the middle layers (approximately 25% of all layers), while early and late layers contribute only marginally.(iii) Fine-grained visual attributes and object details are directly extracted from image tokens in a spatially localized manner, i.e., the generated tokens associated with a specific object or attribute attend strongly to their corresponding regions in the image. We propose novel quantitative evaluation to validate our observations, leveraging real-world complex visual scenes. Finally, we demonstrate the potential of our findings in facilitating efficient visual processing in state-of-the-art VLMs.