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Sync cellpopage

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  1. README.md +38 -0
  2. cellpopage.pt +3 -0
  3. config.json +34 -0
README.md ADDED
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+ ---
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+ license: bsd-3-clause
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+ library_name: pyaging
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+ tags:
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+ - pyaging
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+ - aging-clock
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+ - biology
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+ - dna-methylation
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+ ---
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+
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+ # cellpopage
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+
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+ CellPopAge is an elastic-net DNA-methylation clock using 42 selected CpGs to predict passage-based age of serially cultured adult primary human fibroblast populations and screen compounds that decelerate this measure.
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+
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+ | | |
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+ |---|---|
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+ | **Predicts** | cell-population passage age |
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+ | **Species** | Homo sapiens |
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+ | **Tissue** | cultured fibroblasts |
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+ | **Data type** | DNA methylation |
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+ | **Model type** | elastic net regression |
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+ | **Year** | 2024 |
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+
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+ ## Use with pyaging
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+
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+ ```python
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+ import pyaging as pya
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+
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+ pya.pred.predict_age(adata, ["cellpopage"])
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+ ```
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+
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+ Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
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+
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+ ## Citation
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+
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+ Lujan, Celia, et al. "An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo." Genome Medicine 16 (2024): 85.
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+
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+ https://doi.org/10.1186/s13073-024-01349-w
cellpopage.pt ADDED
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:0ef38f53a061e3a649fd6a2f51ebeae8253674f7196da26805ad70931d3cb9bc
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+ size 75621
config.json ADDED
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+ {
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+ "approved_by_author": "\u231b",
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+ "citation": "Lujan, Celia, et al. \"An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo.\" Genome Medicine 16 (2024): 85.",
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+ "citations": 6,
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+ "citations_date": "2026-07-05",
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+ "clock_name": "cellpopage",
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+ "data_type": "DNA methylation",
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+ "doi": "https://doi.org/10.1186/s13073-024-01349-w",
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+ "journal": "Genome Medicine",
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+ "last_author": "Ivana Bjedov",
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+ "model_type": "elastic net regression",
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+ "n_features": 42,
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+ "notes": "CellPopAge is an elastic-net DNA-methylation clock using 42 selected CpGs to predict passage-based age of serially cultured adult primary human fibroblast populations and screen compounds that decelerate this measure.",
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+ "platform": [
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+ "Illumina EPIC"
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+ ],
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+ "population": "human cell cultures",
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+ "predicts": [
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+ "cell-population passage age"
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+ ],
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+ "research_only": null,
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+ "species": "Homo sapiens",
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+ "tissue": [
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+ "cultured fibroblasts"
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+ ],
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+ "training_target": [
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+ "cell passage number"
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+ ],
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+ "unit": [
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+ "passages"
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+ ],
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+ "version": "v0.3.0",
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+ "year": 2024
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+ }