Correct publication references, input guidance and output units
Browse files- README.md +1 -1
- config.json +1 -1
- cpgptpcgrimage3.pt +2 -2
README.md
CHANGED
|
@@ -9,7 +9,7 @@ tags:
|
|
| 9 |
|
| 10 |
# cpgptpcgrimage3
|
| 11 |
|
| 12 |
-
Principal-component CpGPTGrimAge3 implementation combining chronological age, GrimAge2 DNAm proxies, and CpGPT-predicted plasma-protein proxies; 30 proxy inputs are projected to 29 PCs, entered with age into a Cox linear predictor, and calibrated to years.
|
| 13 |
|
| 14 |
Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.
|
| 15 |
|
|
|
|
| 9 |
|
| 10 |
# cpgptpcgrimage3
|
| 11 |
|
| 12 |
+
Principal-component CpGPTGrimAge3 implementation combining chronological age, GrimAge2 DNAm proxies, and CpGPT-predicted plasma-protein proxies; 30 proxy inputs are projected to 29 PCs, entered with age into a Cox linear predictor, and calibrated to years. Supply derived methylation protein/lifestyle proxies and age, not a raw CpG matrix or measured proteomics. CpGPT protein proxies come from the proteins checkpoint on its trained standardized scale; required proxies must be present.
|
| 13 |
|
| 14 |
Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.
|
| 15 |
|
config.json
CHANGED
|
@@ -10,7 +10,7 @@
|
|
| 10 |
"last_author": "Bo Wang",
|
| 11 |
"model_type": "PCA + Cox regression",
|
| 12 |
"n_features": 31,
|
| 13 |
-
"notes": "Principal-component CpGPTGrimAge3 implementation combining chronological age, GrimAge2 DNAm proxies, and CpGPT-predicted plasma-protein proxies; 30 proxy inputs are projected to 29 PCs, entered with age into a Cox linear predictor, and calibrated to years.",
|
| 14 |
"platform": [
|
| 15 |
"Illumina 450K"
|
| 16 |
],
|
|
|
|
| 10 |
"last_author": "Bo Wang",
|
| 11 |
"model_type": "PCA + Cox regression",
|
| 12 |
"n_features": 31,
|
| 13 |
+
"notes": "Principal-component CpGPTGrimAge3 implementation combining chronological age, GrimAge2 DNAm proxies, and CpGPT-predicted plasma-protein proxies; 30 proxy inputs are projected to 29 PCs, entered with age into a Cox linear predictor, and calibrated to years. Supply derived methylation protein/lifestyle proxies and age, not a raw CpG matrix or measured proteomics. CpGPT protein proxies come from the proteins checkpoint on its trained standardized scale; required proxies must be present.",
|
| 14 |
"platform": [
|
| 15 |
"Illumina 450K"
|
| 16 |
],
|
cpgptpcgrimage3.pt
CHANGED
|
@@ -1,3 +1,3 @@
|
|
| 1 |
version https://git-lfs.github.com/spec/v1
|
| 2 |
-
oid sha256:
|
| 3 |
-
size
|
|
|
|
| 1 |
version https://git-lfs.github.com/spec/v1
|
| 2 |
+
oid sha256:5b3ffaf5c54f9ae9b68f68e059f912bb37acceeb162486d79224156baea28fbc
|
| 3 |
+
size 16470
|