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library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---
# dnamfili
Epigenetic frailty risk score (eFRS), a weighted 20-CpG whole-blood DNA-methylation score selected by LASSO from replicated frailty-associated loci.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| | |
|---|---|
| **Predicts** | frailty risk |
| **Species** | Homo sapiens |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | LASSO regression |
| **Year** | 2022 |
## Use with pyaging
```python
import pyaging as pya
pya.pred.predict_age(adata, ["dnamfili"])
```
Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
## Citation
Li, X. et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nature Communications 13, 5269 (2022).
https://doi.org/10.1038/s41467-022-32893-x
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