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---
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---

# grimage2b2m

B2M is linked to kidney function, cardiovascular disease and inflammation; DNAm B2M is a GrimAge component.

Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.

| | |
|---|---|
| **Predicts** | beta-2-microglobulin |
| **Species** | Homo sapiens |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | elastic net regression |
| **Year** | 2022 |

## Use with pyaging

```python
import pyaging as pya

pya.pred.predict_age(adata, ["grimage2b2m"])
```

Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).

## Citation

Lu, A. T., et al. “DNA methylation GrimAge version 2.” Aging 14(23): 9484–9549 (2022).

https://doi.org/10.18632/aging.204434