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library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
---
# grimage2packyrs
DNAm PACKYRS is a methylation surrogate for cumulative smoking exposure and a GrimAge component.
Model weights retain the original authors' terms; the pyaging software license does not relicense them. These weights are restricted to research use under the authors' terms.
| | |
|---|---|
| **Predicts** | smoking exposure |
| **Species** | Homo sapiens |
| **Tissue** | whole blood |
| **Data type** | DNA methylation |
| **Model type** | elastic net regression |
| **Year** | 2022 |
## Use with pyaging
```python
import pyaging as pya
pya.pred.predict_age(adata, ["grimage2packyrs"])
```
Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
## Citation
Lu, A. T., et al. “DNA methylation GrimAge version 2.” Aging 14(23): 9484–9549 (2022).
https://doi.org/10.18632/aging.204434
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