| { |
| "approved_by_author": "\u231b", |
| "citation": "Lu, A. T., et al. \u201cDNA methylation GrimAge version 2.\u201d Aging 14(23): 9484\u20139549 (2022).", |
| "citations": 291, |
| "citations_date": "2026-07-05", |
| "clock_name": "grimage2packyrs", |
| "data_type": "DNA methylation", |
| "doi": "https://doi.org/10.18632/aging.204434", |
| "journal": "Aging", |
| "last_author": "Steve Horvath", |
| "model_type": "elastic net regression", |
| "n_features": 173, |
| "notes": "DNAm PACKYRS is a methylation surrogate for cumulative smoking exposure and a GrimAge component.", |
| "platform": [ |
| "Illumina 450K" |
| ], |
| "population": "older adults", |
| "postprocess": "cox_to_years", |
| "predicts": [ |
| "smoking exposure" |
| ], |
| "reference_values": true, |
| "research_only": true, |
| "species": "Homo sapiens", |
| "tissue": [ |
| "whole blood" |
| ], |
| "training_target": [ |
| "smoking exposure" |
| ], |
| "unit": [ |
| "pack-years" |
| ], |
| "version": "0.5.0", |
| "year": 2022 |
| } |
