lucascamillomd commited on
Commit
2b4245b
·
verified ·
1 Parent(s): 6c2be8d

Sync grimage2pai1

Browse files
Files changed (3) hide show
  1. README.md +38 -0
  2. config.json +35 -0
  3. grimage2pai1.pt +3 -0
README.md ADDED
@@ -0,0 +1,38 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ ---
2
+ license: bsd-3-clause
3
+ library_name: pyaging
4
+ tags:
5
+ - pyaging
6
+ - aging-clock
7
+ - biology
8
+ - dna-methylation
9
+ ---
10
+
11
+ # grimage2pai1
12
+
13
+ PAI-1 is linked to inflammation and metabolic conditions; DNAm PAI-1 is a GrimAge component.
14
+
15
+ | | |
16
+ |---|---|
17
+ | **Predicts** | PAI-1 |
18
+ | **Species** | Homo sapiens |
19
+ | **Tissue** | whole blood |
20
+ | **Data type** | DNA methylation |
21
+ | **Model type** | elastic net regression |
22
+ | **Year** | 2022 |
23
+
24
+ ## Use with pyaging
25
+
26
+ ```python
27
+ import pyaging as pya
28
+
29
+ pya.pred.predict_age(adata, ["grimage2pai1"])
30
+ ```
31
+
32
+ Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
33
+
34
+ ## Citation
35
+
36
+ Lu, A. T., et al. “DNA methylation GrimAge version 2.” Aging 14(23): 9484–9549 (2022).
37
+
38
+ https://doi.org/10.18632/aging.204434
config.json ADDED
@@ -0,0 +1,35 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ {
2
+ "approved_by_author": "\u231b",
3
+ "citation": "Lu, A. T., et al. \u201cDNA methylation GrimAge version 2.\u201d Aging 14(23): 9484\u20139549 (2022).",
4
+ "citations": 291,
5
+ "citations_date": "2026-07-05",
6
+ "clock_name": "grimage2pai1",
7
+ "data_type": "DNA methylation",
8
+ "doi": "https://doi.org/10.18632/aging.204434",
9
+ "journal": "Aging",
10
+ "last_author": "Steve Horvath",
11
+ "model_type": "elastic net regression",
12
+ "n_features": 211,
13
+ "notes": "PAI-1 is linked to inflammation and metabolic conditions; DNAm PAI-1 is a GrimAge component.",
14
+ "platform": [
15
+ "Illumina 450K"
16
+ ],
17
+ "population": "older adults",
18
+ "predicts": [
19
+ "PAI-1"
20
+ ],
21
+ "reference_values": true,
22
+ "research_only": true,
23
+ "species": "Homo sapiens",
24
+ "tissue": [
25
+ "whole blood"
26
+ ],
27
+ "training_target": [
28
+ "PAI-1"
29
+ ],
30
+ "unit": [
31
+ "picograms per milliliter"
32
+ ],
33
+ "version": "v0.3.0",
34
+ "year": 2022
35
+ }
grimage2pai1.pt ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:d539fe532f485b56bc9cff16f0bbe88b121cedb41bff76216d7771a6e99a4690
3
+ size 12069