Sync hep
Browse files- README.md +38 -0
- config.json +34 -0
- hep.pt +3 -0
README.md
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---
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license: bsd-3-clause
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library_name: pyaging
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tags:
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- pyaging
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- aging-clock
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- biology
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- dna-methylation
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---
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# hep
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HepClock is a hepatocyte-specific chronological-age clock trained by lasso on hepatocyte age-DMCTs identified with CellDMC after estimating five liver cell fractions.
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|---|---|
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| **Predicts** | chronological age |
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| **Species** | Homo sapiens |
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| **Tissue** | liver |
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| **Data type** | DNA methylation |
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| **Model type** | LASSO regression |
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| **Year** | 2024 |
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## Use with pyaging
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```python
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import pyaging as pya
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pya.pred.predict_age(adata, ["hep"])
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```
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Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
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## Citation
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Tong, Huige, et al. "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution." Aging 16 (2024): 14204–14237.
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https://doi.org/10.18632/aging.206184
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config.json
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{
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"approved_by_author": "\u231b",
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"citation": "Tong, Huige, et al. \"Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution.\" Aging 16 (2024): 14204\u201314237.",
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"citations": 25,
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"citations_date": "2026-07-05",
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"clock_name": "hep",
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"data_type": "DNA methylation",
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"doi": "https://doi.org/10.18632/aging.206184",
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"journal": "Aging",
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"last_author": "Andrew E. Teschendorff",
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"model_type": "LASSO regression",
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"n_features": 70,
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"notes": "HepClock is a hepatocyte-specific chronological-age clock trained by lasso on hepatocyte age-DMCTs identified with CellDMC after estimating five liver cell fractions.",
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"platform": [
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"Illumina EPIC"
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],
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"population": "adults",
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"predicts": [
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"chronological age"
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],
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"research_only": null,
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"species": "Homo sapiens",
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"tissue": [
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"liver"
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],
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"training_target": [
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"chronological age"
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],
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"unit": [
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"years"
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],
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"version": "v0.3.0",
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"year": 2024
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}
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hep.pt
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version https://git-lfs.github.com/spec/v1
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oid sha256:197b0a8eb5e78fdb92375b2382a13ddb94367cf3ea366f059edfea26dd3b66a2
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size 6245
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