Correct publication references, input guidance and output units
Browse files- README.md +1 -1
- config.json +1 -1
- mccartneyldlcholesterol.pt +2 -2
README.md
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# mccartneyldlcholesterol
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Whole-blood DNAm LASSO score for LDL with remnant cholesterol, trained in Generation Scotland on an age-, sex-, and ancestry-adjusted phenotype residual and evaluated out of sample in LBC1936.
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Model weights retain the original authors' terms; the pyaging software license does not relicense them.
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# mccartneyldlcholesterol
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Whole-blood DNAm LASSO score for LDL with remnant cholesterol, trained in Generation Scotland on an age-, sex-, and ancestry-adjusted phenotype residual and evaluated out of sample in LBC1936. The current pyaging implementation applies a sigmoid to the linear score, so the returned value is bounded and unitless. It is neither the original continuous phenotype residual nor a calibrated probability; the paper does not specify this sigmoid.
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Model weights retain the original authors' terms; the pyaging software license does not relicense them.
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config.json
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"last_author": "Riccardo E. Marioni",
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"model_type": "LASSO regression",
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"n_features": 233,
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"notes": "Whole-blood DNAm LASSO score for LDL with remnant cholesterol, trained in Generation Scotland on an age-, sex-, and ancestry-adjusted phenotype residual and evaluated out of sample in LBC1936.",
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"platform": [
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"Illumina EPIC"
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],
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"last_author": "Riccardo E. Marioni",
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"model_type": "LASSO regression",
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"n_features": 233,
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"notes": "Whole-blood DNAm LASSO score for LDL with remnant cholesterol, trained in Generation Scotland on an age-, sex-, and ancestry-adjusted phenotype residual and evaluated out of sample in LBC1936. The current pyaging implementation applies a sigmoid to the linear score, so the returned value is bounded and unitless. It is neither the original continuous phenotype residual nor a calibrated probability; the paper does not specify this sigmoid.",
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"platform": [
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"Illumina EPIC"
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],
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mccartneyldlcholesterol.pt
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version https://git-lfs.github.com/spec/v1
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oid sha256:
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size
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version https://git-lfs.github.com/spec/v1
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size 12581
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