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"created": "2026-10-02",
"authors": {
"PCBrainAge": {
"repository": "https://github.com/MorganLevineLab/calcPCBrainAge",
"commit": "8a4a0bf93fe715e48d495af46edf17f10d988afa",
"doi": "10.18632/aging.204196",
"license_declaration": "MIT License",
"license_source": "DESCRIPTION",
"separate_license_file": false
},
"PCGrimAge": {
"repository": "https://github.com/MorganLevineLab/PC-Clocks",
"commit": "5e65bce1eeb600949fce0853e46ed2aa6210051d",
"doi": "10.1038/s43587-022-00248-2",
"weights_url": "https://yale.app.box.com/s/kq0b0a7lxckxjvaz7x5n4keaug7tewry",
"weights_file_id": "904007593153",
"license_declaration": null,
"license_note": "No explicit code or weight license was found in the pinned original PC-Clocks repository."
}
},
"source_sha256": {
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},
"derivation": "Original double-precision PCA rotation multiplied by original regression; subtract centered weighted mean from original intercept. Selected sex and age coefficients retained unchanged.",
"reference_engine": "R 4.5.3 (2026-03-11), arm64",
"oracle": "PCBrainAge: unmodified author calcPCBrainAge function; PCGrimAge components: unmodified PCA and eight prediction assignment lines from author run_calcPCClocks.R",
"third_party_reimplementations_used": false,
"input_contract": "PCBrainAge includes all 357,852 original cg/ch probes. PCGrimAge proxies require finite supplied age/female only when selected by the original component, with no demographic defaults. Missing methylation probes use original author reference means.",
"clock_name": "pcbrainage",
"source_model": "PCBrainAge_Model",
"artifact_sha256": "61f52de2e59ae5d586e77f085ac4ecf100bebfad6f930d3066b743e517e1b763",
"coefficient_archive_sha256": "fa7ef1945d2736fafeee7010b32ab76675fd3db9d9c4e5774c80918e67bd6ab3"
}
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