| { | |
| "approved_by_author": "\u231b", | |
| "citation": "Kasamoto, K., Gibson, J., Moqri, M., Smith, R. & Higgins-Chen, A.T. DNA methylation signatures of cellular senescence are not reversed by senolytic treatment. Aging Cell 25, e70430 (2026).", | |
| "citations": 0, | |
| "citations_date": "2026-10-02", | |
| "clock_name": "senmortalityage", | |
| "data_type": "DNA methylation", | |
| "doi": "https://doi.org/10.1111/acel.70430", | |
| "journal": "Aging Cell", | |
| "last_author": "Albert T. Higgins-Chen", | |
| "model_type": "elastic net Cox regression", | |
| "n_features": 91, | |
| "notes": "Senescence-enriched elastic-net Cox predictor of mortality, restricted to direction-concordant senescence/age/mortality CpGs and trained in the Framingham Heart Study.", | |
| "platform": [ | |
| "Illumina 450K", | |
| "Illumina EPIC" | |
| ], | |
| "population": "adults", | |
| "predicts": [ | |
| "mortality risk" | |
| ], | |
| "research_only": null, | |
| "species": "Homo sapiens", | |
| "tissue": [ | |
| "whole blood" | |
| ], | |
| "training_target": [ | |
| "mortality" | |
| ], | |
| "unit": [ | |
| "log hazard" | |
| ], | |
| "version": "0.5.7", | |
| "year": 2026 | |
| } |