Sync senmortalityage
Browse files- README.md +38 -0
- config.json +35 -0
- senmortalityage.pt +3 -0
README.md
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---
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license: bsd-3-clause
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library_name: pyaging
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tags:
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- pyaging
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- aging-clock
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- biology
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- dna-methylation
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---
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# senmortalityage
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Senescence-enriched elastic-net Cox predictor of mortality, restricted to direction-concordant senescence/age/mortality CpGs and trained in the Framingham Heart Study.
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|---|---|
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| **Predicts** | mortality risk |
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| **Species** | Homo sapiens |
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| **Tissue** | whole blood |
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| **Data type** | DNA methylation |
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| **Model type** | elastic net Cox regression |
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| **Year** | 2026 |
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## Use with pyaging
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```python
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import pyaging as pya
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pya.pred.predict_age(adata, ["senmortalityage"])
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```
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Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
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## Citation
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Kasamoto, K., Gibson, J., Moqri, M., Smith, R. & Higgins-Chen, A.T. DNA methylation signatures of cellular senescence are not reversed by senolytic treatment. Aging Cell 25, e70430 (2026).
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https://doi.org/10.1111/acel.70430
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config.json
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{
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"approved_by_author": "\u231b",
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"citation": "Kasamoto, K., Gibson, J., Moqri, M., Smith, R. & Higgins-Chen, A.T. DNA methylation signatures of cellular senescence are not reversed by senolytic treatment. Aging Cell 25, e70430 (2026).",
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"citations": 0,
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"citations_date": "2026-07-05",
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"clock_name": "senmortalityage",
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"data_type": "DNA methylation",
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"doi": "https://doi.org/10.1111/acel.70430",
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"journal": "Aging Cell",
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"last_author": "Albert T. Higgins-Chen",
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"model_type": "elastic net Cox regression",
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"n_features": 91,
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"notes": "Senescence-enriched elastic-net Cox predictor of mortality, restricted to direction-concordant senescence/age/mortality CpGs and trained in the Framingham Heart Study.",
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"platform": [
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"Illumina 450K",
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"Illumina EPIC"
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],
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"population": "adults",
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"predicts": [
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"mortality risk"
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],
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"research_only": null,
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"species": "Homo sapiens",
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"tissue": [
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"whole blood"
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],
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"training_target": [
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"mortality"
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],
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"unit": [
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"log hazard"
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],
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"version": "v0.3.0",
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"year": 2026
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}
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senmortalityage.pt
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version https://git-lfs.github.com/spec/v1
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oid sha256:ec46548a5d88b96aaebcb2f08872d1c2e8e3de7a214253c4f27eed0f728b7692
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size 6949
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