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Sync stubbs

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  1. README.md +38 -0
  2. config.json +44 -0
  3. stubbs.pt +3 -0
README.md ADDED
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+ ---
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+ license: bsd-3-clause
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+ library_name: pyaging
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+ tags:
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+ - pyaging
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+ - aging-clock
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+ - biology
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+ - dna-methylation
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+ ---
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+
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+ # stubbs
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+
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+ Mouse multi-tissue RRBS age predictor: 17,992 common input loci are normalized and reduced to 329 nonzero clock sites, then quadratically calibrated.
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+
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+ | | |
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+ |---|---|
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+ | **Predicts** | chronological age |
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+ | **Species** | Mus musculus |
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+ | **Tissue** | multi-tissue, liver, lung, heart, brain cortex, skeletal muscle, cerebellum, spleen |
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+ | **Data type** | DNA methylation |
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+ | **Model type** | quadratically calibrated elastic net regression |
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+ | **Year** | 2017 |
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+
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+ ## Use with pyaging
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+
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+ ```python
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+ import pyaging as pya
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+
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+ pya.pred.predict_age(adata, ["stubbs"])
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+ ```
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+
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+ Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io).
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+
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+ ## Citation
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+
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+ Stubbs, T. M., et al. “Multi-tissue DNA methylation age predictor in mouse.” Genome Biology 18: 68 (2017).
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+
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+ https://doi.org/10.1186/s13059-017-1203-5
config.json ADDED
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+ {
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+ "approved_by_author": "\u231b",
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+ "citation": "Stubbs, T. M., et al. \u201cMulti-tissue DNA methylation age predictor in mouse.\u201d Genome Biology 18: 68 (2017).",
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+ "citations": 430,
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+ "citations_date": "2026-07-05",
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+ "clock_name": "stubbs",
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+ "data_type": "DNA methylation",
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+ "doi": "https://doi.org/10.1186/s13059-017-1203-5",
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+ "journal": "Genome Biology",
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+ "last_author": "Wolf Reik",
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+ "model_type": "quadratically calibrated elastic net regression",
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+ "n_features": 17992,
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+ "notes": "Mouse multi-tissue RRBS age predictor: 17,992 common input loci are normalized and reduced to 329 nonzero clock sites, then quadratically calibrated.",
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+ "platform": [
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+ "RRBS"
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+ ],
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+ "population": "mice",
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+ "postprocess": "stubbs",
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+ "predicts": [
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+ "chronological age"
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+ ],
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+ "preprocess": "quantile_normalization_and_scale_with_gold_standard",
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+ "reference_values": true,
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+ "research_only": null,
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+ "species": "Mus musculus",
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+ "tissue": [
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+ "multi-tissue",
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+ "liver",
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+ "lung",
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+ "heart",
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+ "brain cortex",
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+ "skeletal muscle",
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+ "cerebellum",
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+ "spleen"
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+ ],
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+ "training_target": [
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+ "chronological age"
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+ ],
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+ "unit": [
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+ "months"
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+ ],
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+ "version": "v0.3.0",
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+ "year": 2017
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+ }
stubbs.pt ADDED
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:f695cbdca56e28f46928e25dddaff47603730207ab88c73421b40021a80cb8a4
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+ size 766949