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README.md
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- `final_model.pt` — RNA-FM + FEGSTrans adapter + 38-dim biophysics + MLP head, 426 MB
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- `norm_stats.npz` — biophysics feature mean/std (must accompany the checkpoint)
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- `model_card.json` — machine-readable training/eval metadata (includes internal training lineage for reproducibility)
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## Architecture
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2. **FEGSTrans adapter** that pools backbone embeddings with a structural FEGS bias
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3. **38 biophysical features** (MFE, GC%, G4-potential, self-complementarity, etc.)
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Trained on a strict protein-free RNA-LLPS corpus (
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the
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## Headline numbers
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| Metric | Value |
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| 5-fold cluster-grouped CV AUROC | **0.
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| Structural-specificity AUROC | **0.
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| Non-yeast generalization AUROC | **0.
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| Matched-pair accuracy (held-out) | **1.00**
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| Hard-18 held-out AUROC | **0.812** |
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| Mean margin (pos − neg) on matched pairs | **+0.130** |
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## Programmatic use
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- `final_model.pt` — RNA-FM + FEGSTrans adapter + 38-dim biophysics + MLP head, 426 MB
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- `norm_stats.npz` — biophysics feature mean/std (must accompany the checkpoint)
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## Architecture
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2. **FEGSTrans adapter** that pools backbone embeddings with a structural FEGS bias
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3. **38 biophysical features** (MFE, GC%, G4-potential, self-complementarity, etc.)
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Trained on a strict protein-free RNA-LLPS corpus (positives + negatives +
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structural hard negatives) plus matched training pairs that teach the model
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the free-vs-sequestered G-tract distinction — closing the structure-specificity
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blind spot of earlier training recipes.
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## Headline numbers
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| Metric | Value |
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| 5-fold cluster-grouped CV AUROC | **0.88** |
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| Structural-specificity AUROC | **0.90** |
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| Non-yeast generalization AUROC | **0.80** |
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| Matched-pair accuracy (held-out) | **1.00** |
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## Programmatic use
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