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README.md
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@@ -47,12 +47,14 @@ architecture, hyperparameters, training epoch and validation loss, readable
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without loading the checkpoint.
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`esmc_human_cache.pt` (95 MB) sits at the repository root and is required by the
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three `_esmc` checkpoints
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## Use
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without loading the checkpoint.
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`esmc_human_cache.pt` (95 MB) sits at the repository root and is required by the
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three `_esmc` checkpoints, which use it as a frozen lookup table instead of
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learning their feature embeddings. It holds one 1152-dimensional vector per
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UniProt accession: ESM-C 600M run over the canonical human proteome, mean-pooled
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per sequence. It can be recomputed, but that means downloading a
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600M-parameter model and running inference over 20,000 sequences. Shipping it
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keeps the embeddings bit-identical to what the models saw during training, and
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lets anyone run inference with the `_esmc` checkpoints straight away. The
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`learned` checkpoints do not need it.
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## Use
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