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<h1>MORAD</h1>
<p><b>Reinforcement Learning with Multi-Objective Rewards for RNA Inverse Design</b></p>
<p>MORAD post-trains a single backbone-conditioned RNA diffusion policy online with a six-objective reward covering tertiary geometry, base pairing, ensemble behavior and sequence composition. The trained policy designs sequences for a new target backbone directly, with no per-target optimization.</p>
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<li>🧬 <a href="https://huggingface.co/MORAD-RNA/MORAD-RIDE" target="_blank"><b>MORAD-RIDE</b></a>: the released model, post-trained from pretrained RIDE</li>
<li>📦 <a href="https://huggingface.co/datasets/MORAD-RNA/MORAD-Targets" target="_blank"><b>MORAD-Targets</b></a>: 527 training and 153 test RNA backbone targets</li>
<li>💻 <a href="https://github.com/Gabrile166/MORAD" target="_blank"><b>Code</b></a>: training, evaluation and reproduction scripts</li>
<li>🌐 <a href="https://gabrile166.github.io/MORAD/" target="_blank"><b>Project page</b></a>: overview, method and results</li>
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