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import { useEffect, useRef, useState } from 'react';
import { CircleNotch as LoaderCircle, DownloadSimple as Download } from '@phosphor-icons/react';
import { downloadText } from '@/lib/export-utils';
interface Props {
stId: string;
geneName?: string;
height?: number;
}
declare global {
interface Window {
Reactome?: {
Diagram: {
create: (params: {
placeHolder: string;
width?: number;
height?: number;
proxyPrefix?: string;
}) => {
loadDiagram: (stId: string) => void;
flagItems: (term: string) => void;
selectItem: (stId: string) => void;
resetHighlight: () => void;
resetSelection: () => void;
onDiagramLoaded: (cb: (stId: string) => void) => void;
onObjectSelected: (cb: (obj: { stId: string; displayName: string }) => void) => void;
onObjectHovered: (cb: (obj: { stId: string; displayName: string }) => void) => void;
};
};
};
onReactomeDiagramReady?: () => void;
}
}
const ISOLATION_CSS = (id: string) => `
#${id} {
color-scheme: light;
background: #fff;
color: #1a1a2e;
}
#${id} * {
color: revert !important;
background-color: revert !important;
background-image: revert !important;
font-family: revert !important;
font-size: revert !important;
font-weight: revert !important;
line-height: revert !important;
text-align: revert !important;
}
`;
export default function PathwayDiagram({ stId, geneName, height = 400 }: Props) {
const containerId = useRef(`diagram-${stId}-${Math.random().toString(36).slice(2, 8)}`).current;
const [loaded, setLoaded] = useState(false);
const [error, setError] = useState<string | null>(null);
type DiagramInstance = ReturnType<NonNullable<typeof window.Reactome>['Diagram']['create']>;
const diagramRef = useRef<DiagramInstance | null>(null);
const initCalled = useRef(false);
const containerRef = useRef<HTMLDivElement>(null);
const exportSvg = () => {
const svg = containerRef.current?.querySelector('svg');
if (!svg) return;
downloadText(new XMLSerializer().serializeToString(svg), `${stId}_pathway.svg`);
};
const exportPng = () => {
const svg = containerRef.current?.querySelector('svg');
if (!svg) return;
const svgStr = new XMLSerializer().serializeToString(svg);
const canvas = document.createElement('canvas');
const ctx = canvas.getContext('2d')!;
const img = new window.Image();
img.onload = () => {
canvas.width = img.width;
canvas.height = img.height;
ctx.fillStyle = '#ffffff';
ctx.fillRect(0, 0, canvas.width, canvas.height);
ctx.drawImage(img, 0, 0);
const a = document.createElement('a');
a.download = `${stId}_pathway.png`;
a.href = canvas.toDataURL('image/png');
a.click();
};
img.src = 'data:image/svg+xml;base64,' + btoa(unescape(encodeURIComponent(svgStr)));
};
useEffect(() => {
const style = document.createElement('style');
style.textContent = ISOLATION_CSS(containerId);
document.head.appendChild(style);
if (initCalled.current) return;
initCalled.current = true;
if (window.Reactome?.Diagram) {
initDiagram();
return;
}
const script = document.createElement('script');
script.src = 'https://reactome.org/DiagramJs/diagram/diagram.nocache.js';
script.async = true;
script.onerror = () => setError('Failed to load Reactome DiagramJs');
document.head.appendChild(script);
const origReady = window.onReactomeDiagramReady;
window.onReactomeDiagramReady = () => {
origReady?.();
initDiagram();
};
return () => {
style.remove();
if (diagramRef.current) {
diagramRef.current.resetHighlight();
diagramRef.current.resetSelection();
}
};
}, []);
function initDiagram() {
if (!window.Reactome?.Diagram) {
const check = setInterval(() => {
if (window.Reactome?.Diagram) {
clearInterval(check);
createDiagram();
}
}, 200);
setTimeout(() => clearInterval(check), 10000);
return;
}
createDiagram();
}
function createDiagram() {
try {
const diagram = window.Reactome!.Diagram.create({
placeHolder: containerId,
width: 950,
height,
});
diagramRef.current = diagram;
diagram.onDiagramLoaded(() => {
setLoaded(true);
if (geneName) {
diagram.flagItems(geneName);
}
});
diagram.loadDiagram(stId);
} catch {
setError('Failed to initialize diagram viewer');
}
}
return (
<div className="relative">
{loaded && (
<div className="flex items-center justify-end gap-2 mb-2">
<button
onClick={exportSvg}
className="text-xs px-2.5 py-1 rounded bg-surface-1 border border-glass-border text-text-secondary hover:text-accent-cyan transition-colors flex items-center gap-1.5"
>
<Download className="w-3.5 h-3.5" /> SVG
</button>
<button
onClick={exportPng}
className="text-xs px-2.5 py-1 rounded bg-surface-1 border border-glass-border text-text-secondary hover:text-accent-cyan transition-colors flex items-center gap-1.5"
>
<Download className="w-3.5 h-3.5" /> PNG
</button>
</div>
)}
<div ref={containerRef} id={containerId} className="w-full rounded-xl overflow-hidden" style={{ minHeight: height, opacity: loaded ? 1 : 0 }} />
{!loaded && !error && (
<div className="absolute inset-0 flex items-center justify-center bg-surface-1/50 rounded-xl">
<LoaderCircle className="w-6 h-6 animate-spin text-accent-cyan" />
</div>
)}
{error && (
<p className="text-sm text-error">{error}</p>
)}
</div>
);
}
|