fix(pipeline): stop abandoning slow NCBI BLAST jobs + EBI fallback

fix: harden BLAST pipeline against NCBI timeouts and server overload

feat: add query coverage, organism, and query accession to BLAST results

design.md + rules.md compliance: dark theme, teal palette, pulsing dot, Pydantic models, api.ts routing, config fixes, db/max_hits threading, Supabase migration 004

Core pipeline testability: progress callback, rate limiter 429, history table

Initial commit: Bio Nexus pipeline engine — BLAST + UniProt + AlphaFold + AI interpretation (Phase 1)