feat: techspec additions — de novo tier-6 branch, structure export, page capture + final synthesis

feat(pipeline): multi-database UniProt identifier resolution

fix(pipeline): stop abandoning slow NCBI BLAST jobs + EBI fallback

feat(results): in-app share dialog + self-normalized dotplot scoring

feat(admet): ProTox 3.0 ML toxicity prediction — backend client + endpoint, frontend ProTox tab, restored sidebar chevron

feat(seq-tools): motif categories & structure overlay, dot-plot scoring & features, cross-tool links

feat(seq-tools): add sequence utilities, motif scanner and dot plot tools with frontend pages

feat(primers): add NCBI gene search + sequence retrieval, oligo QC and in-silico PCR verification with recharts graphs

feat(docking): Vina full-detail — parse 1.2.7 log (RMSD l.b./u.b., version, seed), RMSD table + run-config UI (3e)

feat(uniprot,domains): reviewed/organism filters + debounce/fast-path, PROSITE raw-sequence scan UI (3c,3d)

feat(alignment): multi-method MSA (clustalo/muscle/kalign/mafft/tcoffee) with method selector (3b)

feat(alignment): pairwise global/local alignment via BLAST hit 'Align pair' (3a)

feat(md): verified force field/solvent menu (ff14SB/ff15ipq/ff19SB/amberfb15/CHARMM36 x OBC1/OBC2/GBN2) with alanine-dipeptide createSystem startup probe; explicit errors for invalid combos; dynamic frontend menu

fix(blast): honor program/db/max_hits params, accept DNA queries, poll cap 65 min

fix(md): reflect OXT across C-CA axis so GBSA stops NaNing on Linux CPU

fix(md): add missing C-terminal OXT so unterminated termini (1TIM HIS 248) build in OpenMM

fix(md): BioPython fallback crash on Atom.element.name ('str' object has no attribute 'name')

feat(md): temperature/KE, Rg and SASA traces; fix OpenMM in deployed image

feat(md): real OpenMM production runs with accurate Ca RMSD

fix: harden BLAST pipeline against NCBI timeouts and server overload

feat: expanded Domain & Motif Analysis with all features and cross-project links

test: comprehensive validation & fuzz testing with bug fixes

feat: add smoke-test suite — ADMET/MD/function/docking endpoint validation (27 tests)