Goal: every endpoint and every Streamlit tab must work in a 2-minute
hackathon demo without requiring the demoer to fetch external data.
Code fixes:
- src/api/routes.py + src/agents/tools.py: fix two stale references —
bbb_model.load (not load_model) and bbb_model.predict_with_proba (not
predict_one); also corrects the agent-side default BBB artifact path
from .pkl to .joblib so the auto-resolve in adjust_drug_dose works.
- src/api/routes.py: replace hard-coded _AGENT_DEFAULT_MODEL = google/
gemini-2.0-flash-exp:free (now 404 on OpenRouter) with a fallback
chain probed at orchestrator-build time. Picks the first model that
returns a non-404/429 ping. Override via NEUROBRIDGE_AGENT_MODEL
(single id) or NEUROBRIDGE_AGENT_MODEL_CHAIN (csv).
- src/llm/explainer.py: prepend openai/gpt-oss-20b:free (verified 2026-
05-02) to the explainer fallback chain so /explain/* doesn't fall
back to the deterministic template when free-tier ids churn.
- src/frontend/app.py: drop the en…
Adds the only legitimate BBB <-> MRI bridge in the platform — researcher
lane only. Fusion engine still excludes BBB as a diagnostic modality.
Modules:
- src/models/bbb_permeability_map.py: scalar BBB leakage score in [0,1]
with two modes. heuristic_proxy (default) reuses the 2D resnet18
Alzheimer classifier and computes 1 - P(NonDemented). dce_onnx loads
a real 4D DCE-MRI ONNX model from BBB_PERMEABILITY_DCE_PATH and
averages a normalised Ktrans map; raises a clear FileNotFoundError
with contract documentation when no artifact exists.
- src/research/drug_dose_adjuster.py: pure-function dose revision keyed
on (BBB intact?, drug BBB-permeable?). Permeable drugs see an
aggressive linear cut floored at 30%; non-permeable drugs see a mild
cut floored at 60%; intact BBB returns baseline unchanged. Unknown
drug permeability is treated as permeable (safer). Rationale always
includes the 'research suggestion, not medical advice' disclaimer.
API:
- POST /predict/bbb_permea…
feat(agents): retrieve_context corpus dispatch (reference vs clinical)
Replace top-level _execute_bbb/eeg/mri functions with closure factories
(_make_bbb/eeg/mri_executor) that (a) accept processed_dir so output paths
are no longer hard-coded relative strings, and (b) catch HTTPException from
route calls and re-raise as ValueError with a clean message.
Add build_default_tools(processed_dir=Path("data/processed")) keyword arg
for backwards-compatible parameterization.
Add 4 new tests: processed_dir threading, retrieve short-circuit with no
index, backwards-compat default, and HTTPException → ValueError translation.
Co-Authored-By: Claude Sonnet 4.6 <noreply@anthropic.com>
