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@@ -3,48 +3,66 @@ license: bsd-3-clause
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  library_name: scikit-learn
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  pipeline_tag: tabular-regression
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  tags:
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- - MRI
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- - medical-imaging
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- - ZAP
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- - random-forest
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- - regression
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  ---
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  # ZAP Random Forest Regression Models
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- This repository contains trained random forest regression models for
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- accelerated liver Z-spectrum analysis proton (ZAP) parameter estimation.
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- The release includes models for two acquisition configurations:
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- - 12 frequency offsets for greater acquisition acceleration
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- - 20 frequency offsets for improved quantitative agreement
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- Each configuration estimates:
 
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- - relatively free fraction, \(F_f\)
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- - apparent transverse exchange time, \(T_{2,f}^{\mathrm{ex}}\)
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- - apparent transverse exchange time, \(T_{2,r}^{\mathrm{ex}}\)
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- ## Files
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- `liver_zap_rfr_models_v1.zip` contains the trained scikit-learn models,
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- selected frequency offsets, model manifest, software environment, release
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- notes, license, and integrity checksums.
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  ## Source code
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- https://github.com/vmalis/ZAP-RFR
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  ## Intended use
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- These models support research evaluation of accelerated liver ZAP imaging.
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- They are not medical devices and are not intended for diagnosis or treatment
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- decisions. Application to different scanners, acquisition protocols, tissues,
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- or populations requires independent validation.
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  ## Security
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- The models use Python `joblib` serialization and therefore have Python pickle
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- semantics. Load model files only from trusted sources and verify their
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- SHA-256 checksums before use.
 
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  library_name: scikit-learn
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  pipeline_tag: tabular-regression
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  tags:
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+ - MRI
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+ - medical-imaging
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+ - ZAP
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+ - random-forest
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+ - regression
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  ---
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  # ZAP Random Forest Regression Models
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+ Trained random forest regression models for accelerated liver Z-spectrum analysis proton (ZAP) parameter estimation.
 
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+ ## Model configurations
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+ Two acquisition configurations are provided:
 
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+ - **12 frequency offsets:** greater acquisition acceleration
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+ - **20 frequency offsets:** improved quantitative agreement
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+ ## Model outputs
 
 
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+ Each configuration estimates the following voxel-wise parameters:
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+ $$
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+ F_f,\qquad T_{2,f}^{\mathrm{ex}},\qquad T_{2,r}^{\mathrm{ex}}.
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+ $$
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+
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+ Here:
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+
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+ - \\(F_f\\) is the relatively free fraction.
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+ - \\(T_{2,f}^{\mathrm{ex}}\\) is the apparent transverse exchange time of the relatively free component.
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+ - \\(T_{2,r}^{\mathrm{ex}}\\) is the apparent transverse exchange time of the restricted component.
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+
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+ The restricted fraction is obtained as
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+
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+ $$
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+ F_r = 1-F_f.
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+ $$
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+
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+ ## Model files
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+
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+ The release archive, `liver_zap_rfr_models_v1.zip`, contains:
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+
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+ - trained scikit-learn random forest regression models
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+ - selected frequency offsets for both acquisition configurations
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+ - model manifest
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+ - software-environment information
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+ - release notes
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+ - BSD 3-Clause license
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+ - SHA-256 integrity checksums
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  ## Source code
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+ The associated source code is available at [github.com/vmalis/ZAP-RFR](https://github.com/vmalis/ZAP-RFR).
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  ## Intended use
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+ These models are intended for research evaluation of accelerated liver ZAP imaging. They are not medical devices and are not intended for diagnosis or treatment decisions.
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+
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+ Application to different scanners, acquisition protocols, tissues, or populations requires independent validation.
 
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  ## Security
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+ The models use Python `joblib` serialization and therefore have Python pickle semantics. Load model files only from trusted sources and verify their SHA-256 checksums before use.