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  ---
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  license: bsd-3-clause
 
 
 
 
 
 
 
 
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  ---
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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  ---
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  license: bsd-3-clause
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+ library_name: scikit-learn
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+ pipeline_tag: tabular-regression
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+ tags:
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+ - MRI
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+ - medical-imaging
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+ - ZAP
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+ - random-forest
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+ - regression
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  ---
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+
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+ # Liver ZAP Random Forest Regression Models
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+
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+ This repository contains trained random forest regression models for
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+ accelerated liver Z-spectrum analysis proton (ZAP) parameter estimation.
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+
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+ The release includes models for two acquisition configurations:
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+
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+ - 12 frequency offsets for greater acquisition acceleration
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+ - 20 frequency offsets for improved quantitative agreement
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+
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+ Each configuration estimates:
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+
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+ - relatively free fraction, \(F_f\)
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+ - apparent transverse exchange time, \(T_{2,f}^{\mathrm{ex}}\)
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+ - apparent transverse exchange time, \(T_{2,r}^{\mathrm{ex}}\)
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+
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+ ## Files
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+
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+ `liver_zap_rfr_models_v1.zip` contains the trained scikit-learn models,
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+ selected frequency offsets, model manifest, software environment, release
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+ notes, license, and integrity checksums.
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+
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+ ## Source code
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+
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+ https://github.com/vmalis/ZAP-RFR
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+
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+ ## Intended use
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+
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+ These models support research evaluation of accelerated liver ZAP imaging.
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+ They are not medical devices and are not intended for diagnosis or treatment
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+ decisions. Application to different scanners, acquisition protocols, tissues,
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+ or populations requires independent validation.
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+
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+ ## Security
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+
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+ The models use Python `joblib` serialization and therefore have Python pickle
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+ semantics. Load model files only from trusted sources and verify their
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+ SHA-256 checksums before use.