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README.md
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---
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license: mit
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language:
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- en
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library_name: pytorch
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tags:
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- medical-imaging
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- coronary-artery-segmentation
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- cardiac-ct
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- nnunet
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- imagecas
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---
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# Coronary Artery Segmentation (nnU-Net)
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nnU-Net trained on ImageCAS dataset for coronary artery tree segmentation in cardiac CT angiography (CCTA).
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## Model Details
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- **Architecture**: nnU-Net v2 (3D Residual-Encoder, full resolution)
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- **Input**: 3D CCTA volumes (NIfTI format)
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- **Output**: Coronary artery voxel-wise segmentation
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## Training
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- **Dataset**: ImageCAS (~1,000 CCTA scans)
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- **Split**: Official ImageCAS split (train/val/test)
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- **Fold**: fold_0 (best validation performance)
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## Downstream Pipeline
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Part of multi-stage clinical analysis system:
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1. **Stage 1** (this model): Coronary segmentation
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2. **Stage 2**: Plaque classification (HU-threshold: calcified/non-calcified/LRNC)
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3. **Stage 3**: 3D plaque map reconstruction
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4. **Stage 4**: FFR estimation (research prototype, CFD-capable)
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5. **Stage 5**: Clinical review app with 3D visualization & curved MPR
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## Real Case Examples
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Outputs included demonstrate:
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- Coronary mesh with plaque composition color-coding (phase4_job_case1_v2)
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- Curved MPR for interventionalist visualization
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- Diameter profiling, QC gates, comprehensive reports
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## Citation
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ImageCAS: Huo et al., "Towards Robust Coronary Artery Segmentation in CCTA" (2021)
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nnU-Net: Isensee et al., "nnU-Net: Self-configuring method for deep learning-based biomedical image segmentation" (2021)
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## License
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MIT - See repository for details
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## Disclaimer
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Research model. Not for clinical use without independent validation.
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