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FLARE-AutoMSC Validation Baselines β€” Glioma IDH / Grade

Baseline models for MICCAI FLARE 2026 Task 2 β€” AutoMSC: Automated Medical Image Segmentation and Classification, on the GliomaIDHType cohort (491 multi-sequence brain MRI cases).

Each model jointly performs tumor segmentation and a case-level classification using the multi-task nnUNet framework (nnUNetCLSTrainerMTL). Both models are trained with 5-fold cross-validation and share the same images, labels, and fold splits β€” they differ only in the classification head. This repository contains the best-checkpoint weights (checkpoint_best.pth) for each fold plus the cross-validation evaluation report and figures.

Models

Model Modality Cases Segmentation Classification (cases per class) Mean DSC Mean AUROC
Dataset007_GliomaIDHType FLAIR, T1, T1ce, T2 491 Tumor (1) Grade (3-class): Grade 2 (80), Grade 3 (78), Grade 4 (333) 0.875 0.825
Dataset072_GliomaIDHType FLAIR, T1, T1ce, T2 491 Tumor (1) IDH (binary): wild-type (350), mutated (141) 0.873 0.912

Metrics are means across the 5 CV folds (each case scored by its held-out fold). AUROC is macro for the 3-class grade model and binary for the IDH model. See each model's README.md for per-fold tables and figures.

Repository Structure

DatasetXXX_GliomaIDHType/
β”œβ”€β”€ README.md                                    # per-fold results and figures (same as results.md)
β”œβ”€β”€ results.md
β”œβ”€β”€ figures/                                     # box plots, ROC/PRC, confusion matrix, case samples
└── nnUNetCLSTrainerMTL__nnUNetPlans__3d_fullres/
    β”œβ”€β”€ dataset.json
    β”œβ”€β”€ dataset_fingerprint.json
    β”œβ”€β”€ plans.json
    β”œβ”€β”€ eval_results/                            # per-case CSVs, fold_summary.csv, summary.json
    β”œβ”€β”€ fold_0/
    β”‚   └── checkpoint_best.pth
    β”œβ”€β”€ ...
    └── fold_4/
        └── checkpoint_best.pth

combine_predictions.py (repo root) merges the IDH (binary) and grade (3-class) prediction CSVs into the FLARE-AutoMSC submission format (identifier, idh_wildtype, idh_mutated, grade2, grade3, grade4).

Reproduction

Cross-validation evaluation and figures are produced by fivefold_eval.py and eval-report/generate_figures.py from the AutoMSC-Baseline codebase (github.com/medfm-flare/AutoMSC-Baseline); the raw dataset provides imagesTr/, labelsTr/, splits_final.json, cls_data.csv, and cls_data_idh.csv.

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