Dual-head hybrid CNN-Transformer for brain tumor MRI, leave-one-dataset-out

Weights for the paper Pretraining, Not Architecture, Determines Cross-Institutional Generalization in Brain Tumor MRI Classification.

Code: https://github.com/Ats-Tewe/brain-tumor-lodo

What is here

Four checkpoints, seed 42 throughout. Each is the selected checkpoint, not the last epoch, so each corresponds to a number in the paper.

file protocol held out accuracy
merged_best_model.pth Merged baseline nothing 99.68%
lodo1_best_model.pth LODO Round 1 Kaggle 94.25%
lodo2_best_model.pth LODO Round 2 Figshare 99.34%, three classes
lodo3_best_model.pth LODO Round 3 Mendeley 94.12%

lodo3 is the model behind every calibration, uncertainty and explanation result in the paper.

Loading

import torch
from huggingface_hub import hf_hub_download

path = hf_hub_download("Ha-Te-21/brain-tumor-lodo", "lodo3_best_model.pth")
state = torch.load(path, map_location="cpu")
model.load_state_dict(state.get("model_state_dict", state))
model.eval()

The model class is src/model/model.py in the code repository.

Two things that will bite you

Input is 320 px, not 224. The images are stored at 224 and upsampled at load time. Feeding 224 directly changes the token grid from 10x10 to 7x7 and the position embeddings will not match.

Normalization is ImageNet statistics, not per-image. See src/common/data.py.

What these weights are good for, and what they are not

They reproduce the numbers in the paper. They are not a clinical tool.

The paper's own finding is that five runs of this configuration, differing only in random seed, spanned 12.99 accuracy points on a held-out institution. A single checkpoint is one draw from that distribution. Round 2 in particular evaluates three classes on a test set that is 78% glioma, with its meningioma estimate resting on 58 images; we exclude it from every cross-institutional conclusion and so should you.

Verifying your download

SHA256SUMS is in this repository.

sha256sum -c SHA256SUMS

Citation

See CITATION.cff in the code repository.

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