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Biomedical Nomic Embedding Surgery

This project modifies the tokenizer and embedding layer of:

nomic-ai/nomic-embed-text-v1-unsupervised

Changes

  • Added 15 biomedical domain tokens:
    • glioblastoma
    • immunohistochemistry
    • pharmacogenomics
    • angiogenesis
    • neurodegeneration
    • bioavailability
    • oncogenesis
    • metastasis
    • cytokinemia
    • microvasculature
    • electrophysiology
    • histopathology
    • chemoresistance
    • osteogenesis
    • hepatocarcinogenesis

Method

New embeddings were initialized by averaging existing sub-token embeddings.

Example:

glioblastoma: [g, ##lio, ##bla, ##sto, ##ma]

The resulting embedding was inserted into the expanded embedding matrix.

Verification

  • Original embeddings unchanged: True

  • New vocabulary size: 30537 tokenizer tokens

  • Embedding matrix: 30592 x 768

  • End-to-end inference verified successfully.

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