| --- |
| dataset_info: |
| features: |
| - name: seqs |
| dtype: string |
| - name: labels |
| dtype: int64 |
| splits: |
| - name: train |
| num_bytes: 88951983 |
| num_examples: 283057 |
| - name: valid |
| num_bytes: 19213838 |
| num_examples: 62973 |
| - name: test |
| num_bytes: 22317993 |
| num_examples: 73205 |
| download_size: 127755417 |
| dataset_size: 130483814 |
| configs: |
| - config_name: default |
| data_files: |
| - split: train |
| path: data/train-* |
| - split: valid |
| path: data/valid-* |
| - split: test |
| path: data/test-* |
| --- |
| |
| # INFORMATION FROM [HERE](https://huggingface.co/datasets/biomap-research/temperature_stability) PLEASE CITE THEIR PAPER BELOW |
|
|
| ### Dataset Summary |
|
|
| The accurate prediction of protein thermal stability has far-reaching implications in both academic and industrial spheres. This task primarily aims to predict a protein’s capacity to preserve its structural stability under a temperature condition of 65 degrees Celsius. |
|
|
| ## Dataset Structure |
|
|
| ### Data Instances |
| For each instance, there is a string representing the protein sequence and an integer label indicating whether the protein can maintain its structural stability at a temperature of 65 degrees Celsius. See the [temperature stability dataset viewer](https://huggingface.co/datasets/Bo1015/temperature_stability/viewer) to explore more examples. |
|
|
| ``` |
| {'seq':'MEHVIDNFDNIDKCLKCGKPIKVVKLKYIKKKIENIPNSHLINFKYCSKCKRENVIENL' |
| 'label':1} |
| ``` |
|
|
| The average for the `seq` and the `label` are provided below: |
|
|
| | Feature | Mean Count | |
| | ---------- | ---------------- | |
| | seq | 300 | |
|
|
|
|
| ### Data Fields |
|
|
| - `seq`: a string containing the protein sequence |
| - `label`: an integer label indicating the structural stability of each sequence. |
|
|
| ### Data Splits |
|
|
| The temperature stability dataset has 3 splits: _train_, _valid_, and _test_. Below are the statistics of the dataset. |
|
|
| | Dataset Split | Number of Instances in Split | |
| | ------------- | ------------------------------------------- | |
| | Train | 283,057 | |
| | Valid | 62,973 | |
| | Test | 73,205 | |
|
|
| ### Source Data |
|
|
| #### Initial Data Collection and Normalization |
|
|
| We adapted the dataset strategy from [TemStaPro](https://academic.oup.com/bioinformatics/article/40/4/btae157/7632735). |
|
|
| ### Licensing Information |
|
|
| The dataset is released under the [Apache-2.0 License](http://www.apache.org/licenses/LICENSE-2.0). |
|
|
| ### Citation |
| If you find our work useful, please consider citing the following paper: |
|
|
| ``` |
| @misc{chen2024xtrimopglm, |
| title={xTrimoPGLM: unified 100B-scale pre-trained transformer for deciphering the language of protein}, |
| author={Chen, Bo and Cheng, Xingyi and Li, Pan and Geng, Yangli-ao and Gong, Jing and Li, Shen and Bei, Zhilei and Tan, Xu and Wang, Boyan and Zeng, Xin and others}, |
| year={2024}, |
| eprint={2401.06199}, |
| archivePrefix={arXiv}, |
| primaryClass={cs.CL}, |
| note={arXiv preprint arXiv:2401.06199} |
| } |
| ``` |
