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The dataset generation failed because of a cast error
Error code: DatasetGenerationCastError
Exception: DatasetGenerationCastError
Message: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 5 new columns ({'Synonyms', 'ParentTreeNumbers', 'TreeNumbers', 'Definition', 'ParentIDs'}) and 9 missing columns ({'GeneForms', 'PubMedIDs', 'GeneSymbol', 'InteractionActions', 'Unnamed: 0.1', 'Interaction', 'GeneID', 'Organism', 'OrganismID'}).
This happened while the csv dataset builder was generating data using
hf://datasets/Nathali99/CTD_datasets/CTD_chemicals.csv (at revision 5c49cb9b97dfe70be6bc4ead382626fa81b25be2), ['hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_chem_gene_ixns.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_chemicals.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_chemicals_diseases.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_diseases.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_genes.csv']
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback: Traceback (most recent call last):
File "/usr/local/lib/python3.14/site-packages/datasets/builder.py", line 1837, in _prepare_split_single
writer.write_table(table)
~~~~~~~~~~~~~~~~~~^^^^^^^
File "/usr/local/lib/python3.14/site-packages/datasets/arrow_writer.py", line 765, in write_table
self._write_table(pa_table, writer_batch_size=writer_batch_size)
~~~~~~~~~~~~~~~~~^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.14/site-packages/datasets/arrow_writer.py", line 773, in _write_table
pa_table = table_cast(pa_table, self._schema)
File "/usr/local/lib/python3.14/site-packages/datasets/table.py", line 2369, in table_cast
return cast_table_to_schema(table, schema)
File "/usr/local/lib/python3.14/site-packages/datasets/table.py", line 2297, in cast_table_to_schema
raise CastError(
...<3 lines>...
)
datasets.table.CastError: Couldn't cast
Unnamed: 0: int64
ChemicalName: string
ChemicalID: string
CasRN: string
Definition: string
ParentIDs: string
TreeNumbers: string
ParentTreeNumbers: string
Synonyms: string
-- schema metadata --
pandas: '{"index_columns": [{"kind": "range", "name": null, "start": 0, "' + 1362
to
{'Unnamed: 0.1': Value('int64'), 'Unnamed: 0': Value('int64'), 'ChemicalName': Value('string'), 'ChemicalID': Value('string'), 'CasRN': Value('string'), 'GeneSymbol': Value('string'), 'GeneID': Value('float64'), 'GeneForms': Value('string'), 'Organism': Value('string'), 'OrganismID': Value('float64'), 'Interaction': Value('string'), 'InteractionActions': Value('string'), 'PubMedIDs': Value('string')}
because column names don't match
During handling of the above exception, another exception occurred:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1369, in compute_config_parquet_and_info_response
parquet_operations, partial, estimated_dataset_info = stream_convert_to_parquet(
~~~~~~~~~~~~~~~~~~~~~~~~~^
builder, max_dataset_size_bytes=max_dataset_size_bytes
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
)
^
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 948, in stream_convert_to_parquet
builder._prepare_split(split_generator=splits_generators[split], file_format="parquet")
~~~~~~~~~~~~~~~~~~~~~~^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.14/site-packages/datasets/builder.py", line 1683, in _prepare_split
for job_id, done, content in self._prepare_split_single(
~~~~~~~~~~~~~~~~~~~~~~~~~~^
gen_kwargs=gen_kwargs, job_id=job_id, **_prepare_split_args
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
):
^
File "/usr/local/lib/python3.14/site-packages/datasets/builder.py", line 1839, in _prepare_split_single
raise DatasetGenerationCastError.from_cast_error(
...<4 lines>...
)
datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 5 new columns ({'Synonyms', 'ParentTreeNumbers', 'TreeNumbers', 'Definition', 'ParentIDs'}) and 9 missing columns ({'GeneForms', 'PubMedIDs', 'GeneSymbol', 'InteractionActions', 'Unnamed: 0.1', 'Interaction', 'GeneID', 'Organism', 'OrganismID'}).
This happened while the csv dataset builder was generating data using
hf://datasets/Nathali99/CTD_datasets/CTD_chemicals.csv (at revision 5c49cb9b97dfe70be6bc4ead382626fa81b25be2), ['hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_chem_gene_ixns.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_chemicals.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_chemicals_diseases.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_diseases.csv', 'hf://datasets/Nathali99/CTD_datasets@5c49cb9b97dfe70be6bc4ead382626fa81b25be2/CTD_genes.csv']
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
Unnamed: 0.1 int64 | Unnamed: 0 int64 | ChemicalName string | ChemicalID string | CasRN null | GeneSymbol string | GeneID float64 | GeneForms string | Organism string | OrganismID float64 | Interaction string | InteractionActions string | PubMedIDs string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 0 | 10074-G5 | C534883 | null | AR | 367 | protein | Homo sapiens | 9,606 | 10074-G5 affects the reaction [MYC protein results in increased expression of AR protein] | affects^reaction|increases^expression | 32184358 |
1 | 1 | 10074-G5 | C534883 | null | AR | 367 | protein | Homo sapiens | 9,606 | 10074-G5 inhibits the reaction [EPHB2 protein modified form results in increased expression of AR protein] | decreases^reaction|increases^expression | 32184358 |
2 | 2 | 10074-G5 | C534883 | null | AR | 367 | protein | Homo sapiens | 9,606 | 10074-G5 results in decreased expression of AR protein | decreases^expression | 32184358 |
3 | 3 | 10074-G5 | C534883 | null | AR | 367 | protein | Homo sapiens | 9,606 | 10074-G5 results in decreased expression of AR protein alternative form | decreases^expression | 32184358 |
4 | 4 | 10074-G5 | C534883 | null | EPHB2 | 2,048 | protein | Homo sapiens | 9,606 | 10074-G5 inhibits the reaction [EPHB2 protein modified form results in increased expression of AR protein] | decreases^reaction|increases^expression | 32184358 |
5 | 5 | 10074-G5 | C534883 | null | EPHB2 | 2,048 | protein | Homo sapiens | 9,606 | 10074-G5 inhibits the reaction [EPHB2 protein modified form results in increased expression of MYC protein] | decreases^reaction|increases^expression | 32184358 |
6 | 6 | 10074-G5 | C534883 | null | MAX | 4,149 | protein | null | null | 10074-G5 affects the folding of and results in decreased activity of [MYC protein binds to MAX protein] | affects^binding|affects^folding|decreases^activity | 26474287 |
7 | 7 | 10074-G5 | C534883 | null | MAX | 4,149 | protein | null | null | 10074-G5 inhibits the reaction [MYC protein binds to MAX protein] | affects^binding|decreases^reaction | 26474287 |
8 | 8 | 10074-G5 | C534883 | null | MYC | 4,609 | protein | Homo sapiens | 9,606 | 10074-G5 affects the reaction [MYC protein results in increased expression of AR protein] | affects^reaction|increases^expression | 32184358 |
9 | 9 | 10074-G5 | C534883 | null | MYC | 4,609 | protein | Homo sapiens | 9,606 | 10074-G5 analog results in decreased expression of MYC protein | decreases^expression | 26036281 |
10 | 10 | 10074-G5 | C534883 | null | MYC | 4,609 | protein | Homo sapiens | 9,606 | 10074-G5 inhibits the reaction [EPHB2 protein modified form results in increased expression of MYC protein] | decreases^reaction|increases^expression | 32184358 |
11 | 11 | 10074-G5 | C534883 | null | MYC | 4,609 | protein | Homo sapiens | 9,606 | 10074-G5 results in decreased activity of MYC protein | decreases^activity | 25716159 |
12 | 12 | 10074-G5 | C534883 | null | MYC | 4,609 | protein | Homo sapiens | 9,606 | 10074-G5 results in decreased expression of MYC protein | decreases^expression | 26036281|32184358 |
13 | 13 | 10074-G5 | C534883 | null | MYC | 4,609 | protein | null | null | 10074-G5 affects the folding of and results in decreased activity of [MYC protein binds to MAX protein] | affects^binding|affects^folding|decreases^activity | 26474287 |
14 | 14 | 10074-G5 | C534883 | null | MYC | 4,609 | protein | null | null | 10074-G5 inhibits the reaction [MYC protein binds to MAX protein] | affects^binding|decreases^reaction | 26474287 |
15 | 15 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone | C112297 | null | FOS | 2,353 | protein | Mus musculus | 10,090 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone inhibits the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of FOS protein]] | decreases^reaction|increases^expression | 26348896 |
16 | 16 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone | C112297 | null | KCNQ1 | 3,784 | protein | null | null | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone results in decreased activity of KCNQ1 protein | decreases^activity | 18568022 |
17 | 17 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone | C112297 | null | KCNQ2 | 3,785 | protein | Homo sapiens | 9,606 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone results in decreased activity of KCNQ2 protein | decreases^activity | 35550413 |
18 | 18 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone | C112297 | null | KCNQ2 | 3,785 | protein | Mus musculus | 10,090 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone affects the reaction [[Potassium results in increased activity of KCNQ2 protein] which results in increased import of Thallium] | affects^reaction|increases^activity|increases^import | 15634793 |
19 | 19 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone | C112297 | null | KCNQ2 | 3,785 | protein | null | null | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone inhibits the reaction [[KCNQ2 protein binds to KCNQ3 protein] which results in increased transport of Thallium] | affects^binding|decreases^reaction|increases^transport | 20208034 |
20 | 20 | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone | C112297 | null | KCNQ3 | 3,786 | protein | null | null | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone inhibits the reaction [[KCNQ2 protein binds to KCNQ3 protein] which results in increased transport of Thallium] | affects^binding|decreases^reaction|increases^transport | 20208034 |
21 | 21 | 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide | C004822 | null | EPHX1 | 2,052 | gene | Homo sapiens | 9,606 | [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide | affects^chemical synthesis|affects^metabolic processing | 15692831 |
22 | 22 | 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide | C004822 | null | EPHX1 | 2,052 | protein | Homo sapiens | 9,606 | [EPHX1 protein results in increased metabolism of carbamazepine epoxide] which results in increased chemical synthesis of 10,11-dihydro-10,11-dihydroxy-5H-dibenzazepine-5-carboxamide | increases^chemical synthesis|increases^metabolic processing | 15692831 |
23 | 23 | 10,11-dihydro-10-hydroxycarbamazepine | C039775 | null | ABCB1 | 5,243 | protein | Homo sapiens | 9,606 | ABCB1 protein results in increased transport of 10,11-dihydro-10-hydroxycarbamazepine | increases^transport | 16190932 |
24 | 24 | 10,11-dihydro-10-hydroxycarbamazepine | C039775 | null | CYP2C19 | 1,557 | protein | null | null | 10,11-dihydro-10-hydroxycarbamazepine results in decreased activity of CYP2C19 protein | decreases^activity | 17516704 |
25 | 25 | 10,11-dihydro-5H-dibenzo(a,d)cycloheptene | C515697 | null | AR | 367 | protein | Rattus norvegicus | 10,116 | 10,11-dihydro-5H-dibenzo(a,d)cycloheptene analog inhibits the reaction [Metribolone binds to AR protein] | affects^binding|decreases^reaction | 3695475 |
26 | 26 | 10,11-dihydro-5H-dibenzo(a,d)cycloheptene | C515697 | null | AR | 367 | protein | Rattus norvegicus | 10,116 | 10,11-dihydro-5H-dibenzo(a,d)cycloheptene inhibits the reaction [Metribolone binds to AR protein] | affects^binding|decreases^reaction | 3695475 |
27 | 27 | 10,12-octadecadienoic acid | C094849 | null | CASP3 | 836 | mRNA | Oryctolagus cuniculus | 9,986 | [9,11-linoleic acid co-treated with 10,12-octadecadienoic acid] results in increased expression of CASP3 mRNA | affects^cotreatment|increases^expression | 31923252 |
28 | 28 | 10,12-octadecadienoic acid | C094849 | null | PPARG | 5,468 | mRNA | Oryctolagus cuniculus | 9,986 | [9,11-linoleic acid co-treated with 10,12-octadecadienoic acid] results in decreased expression of PPARG mRNA | affects^cotreatment|decreases^expression | 31923252 |
29 | 29 | 10,12-octadecadienoic acid | C094849 | null | SCD5 | 79,966 | mRNA | Oryctolagus cuniculus | 9,986 | [9,11-linoleic acid co-treated with 10,12-octadecadienoic acid] results in increased expression of SCD5 mRNA | affects^cotreatment|increases^expression | 31923252 |
30 | 30 | 10-(2-pyrazolylethoxy)camptothecin | C534422 | null | CASP3 | 836 | protein | Homo sapiens | 9,606 | 10-(2-pyrazolylethoxy)camptothecin results in increased activity of CASP3 protein | increases^activity | 18708040 |
31 | 31 | 10-(2-pyrazolylethoxy)camptothecin | C534422 | null | CASP8 | 841 | protein | Homo sapiens | 9,606 | 10-(2-pyrazolylethoxy)camptothecin results in increased activity of CASP8 protein | increases^activity | 18708040 |
32 | 32 | 103D5R | C496879 | null | AKT1 | 207 | protein | Homo sapiens | 9,606 | 103D5R results in decreased phosphorylation of AKT1 protein | decreases^phosphorylation | 15695405 |
33 | 33 | 103D5R | C496879 | null | HIF1A | 3,091 | protein | Homo sapiens | 9,606 | 103D5R inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein] | decreases^reaction|increases^expression | 15695405 |
34 | 34 | 103D5R | C496879 | null | HIF1A | 3,091 | protein | Homo sapiens | 9,606 | 103D5R results in decreased expression of and results in decreased activity of HIF1A protein | decreases^activity|decreases^expression | 15695405 |
35 | 35 | 103D5R | C496879 | null | HIF1A | 3,091 | mRNA | Homo sapiens | 9,606 | 103D5R results in decreased expression of HIF1A mRNA | decreases^expression | 15695405 |
36 | 36 | 103D5R | C496879 | null | MAPK1 | 5,594 | protein | Homo sapiens | 9,606 | 103D5R results in decreased phosphorylation of MAPK1 protein | decreases^phosphorylation | 15695405 |
37 | 37 | 103D5R | C496879 | null | MAPK3 | 5,595 | protein | Homo sapiens | 9,606 | 103D5R results in decreased phosphorylation of MAPK3 protein | decreases^phosphorylation | 15695405 |
38 | 38 | 103D5R | C496879 | null | MAPK8 | 5,599 | protein | Homo sapiens | 9,606 | 103D5R results in decreased phosphorylation of MAPK8 protein | decreases^phosphorylation | 15695405 |
39 | 39 | 103D5R | C496879 | null | SLC2A1 | 6,513 | mRNA | Homo sapiens | 9,606 | 103D5R results in decreased expression of SLC2A1 mRNA | decreases^expression | 15695405 |
40 | 40 | 103D5R | C496879 | null | VEGFA | 7,422 | mRNA | Homo sapiens | 9,606 | 103D5R results in decreased expression of VEGFA mRNA | decreases^expression | 15695405 |
41 | 41 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | GP1BA | 2,811 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein] | decreases^reaction|increases^expression | 20523355 |
42 | 42 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | GP1BA | 2,811 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [THPO protein results in increased expression of GP1BA protein] | decreases^reaction|increases^expression | 20523355 |
43 | 43 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | GYPA | 2,993 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] | decreases^expression|decreases^reaction | 20523355 |
44 | 44 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | ITGA2B | 3,674 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein] | decreases^reaction|increases^expression | 20523355 |
45 | 45 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | ITGA2B | 3,674 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [THPO protein results in increased expression of ITGA2B protein] | decreases^reaction|increases^expression | 20523355 |
46 | 46 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | ITGB3 | 3,690 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein] | decreases^reaction|increases^expression | 20523355 |
47 | 47 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | ITGB3 | 3,690 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [THPO protein results in increased expression of ITGB3 protein] | decreases^reaction|increases^expression | 20523355 |
48 | 48 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | TFEB | 7,942 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine affects the localization of TFEB protein | affects^localization | 28366621 |
49 | 49 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | THPO | 7,066 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [THPO protein results in increased expression of GP1BA protein] | decreases^reaction|increases^expression | 20523355 |
50 | 50 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | THPO | 7,066 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [THPO protein results in increased expression of ITGA2B protein] | decreases^reaction|increases^expression | 20523355 |
51 | 51 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine | C553100 | null | THPO | 7,066 | protein | Homo sapiens | 9,606 | 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [THPO protein results in increased expression of ITGB3 protein] | decreases^reaction|increases^expression | 20523355 |
52 | 52 | 10-(alpha-diethylaminopropionyl)phenothiazine | C013759 | null | HAMP | 57,817 | mRNA | Homo sapiens | 9,606 | 10-(alpha-diethylaminopropionyl)phenothiazine results in decreased expression of HAMP mRNA | decreases^expression | 25633564 |
53 | 53 | 10-carboxymethyl-9-acridanone | C026430 | null | TP53 | 7,157 | protein | Homo sapiens | 9,606 | 10-carboxymethyl-9-acridanone affects the activity of TP53 protein | affects^activity | 35435491 |
54 | 54 | 10-carboxymethyl-9-acridanone | C026430 | null | TP53 | 7,157 | protein | Homo sapiens | 9,606 | 10-carboxymethyl-9-acridanone metabolite affects the activity of TP53 protein | affects^activity | 35435491 |
55 | 55 | 10-deacetylpaclitaxel | C095360 | null | ABCB1 | 5,243 | protein | Homo sapiens | 9,606 | 10-deacetylpaclitaxel binds to ABCB1 protein | affects^binding | 29625142 |
56 | 56 | 10-decarbamoylmitomycin C | C067795 | null | CASP3 | 836 | protein | Homo sapiens | 9,606 | 10-decarbamoylmitomycin C results in increased activity of CASP3 protein | increases^activity | 17530733 |
57 | 57 | 10-decarbamoylmitomycin C | C067795 | null | CASP9 | 842 | protein | Homo sapiens | 9,606 | 10-decarbamoylmitomycin C results in increased activity of CASP9 protein | increases^activity | 17530733 |
58 | 58 | 10-decarbamoylmitomycin C | C067795 | null | CDKN1A | 1,026 | mRNA | Homo sapiens | 9,606 | [10-decarbamoylmitomycin C results in increased stability of TP53 protein] which results in increased expression of CDKN1A mRNA | increases^expression|increases^stability | 20536192 |
59 | 59 | 10-decarbamoylmitomycin C | C067795 | null | CHEK1 | 1,111 | protein | Homo sapiens | 9,606 | 10-decarbamoylmitomycin C results in decreased expression of and results in decreased stability of CHEK1 protein | decreases^expression|decreases^stability | 20536192 |
60 | 60 | 10-decarbamoylmitomycin C | C067795 | null | CHEK1 | 1,111 | mRNA | Homo sapiens | 9,606 | 10-decarbamoylmitomycin C results in decreased expression of CHEK1 mRNA | decreases^expression | 20536192 |
61 | 61 | 10-decarbamoylmitomycin C | C067795 | null | CHEK1 | 1,111 | protein | Homo sapiens | 9,606 | 10-decarbamoylmitomycin C results in decreased expression of CHEK1 protein | decreases^expression | 17530733 |
62 | 62 | 10-decarbamoylmitomycin C | C067795 | null | CHEK1 | 1,111 | protein | Homo sapiens | 9,606 | carbobenzoxy-leucyl-leucyl-norvalinal inhibits the reaction [10-decarbamoylmitomycin C results in decreased expression of CHEK1 protein] | decreases^expression|decreases^reaction | 20536192 |
63 | 63 | 10-decarbamoylmitomycin C | C067795 | null | CHEK1 | 1,111 | protein | Homo sapiens | 9,606 | CHEK1 protein affects the susceptibility to 10-decarbamoylmitomycin C | affects^response to substance | 20536192 |
64 | 64 | 10-decarbamoylmitomycin C | C067795 | null | TP53 | 7,157 | protein | Homo sapiens | 9,606 | 10-decarbamoylmitomycin C results in increased stability of TP53 protein | increases^stability | 20536192 |
65 | 65 | 10-decarbamoylmitomycin C | C067795 | null | TP53 | 7,157 | protein | Homo sapiens | 9,606 | [10-decarbamoylmitomycin C results in increased stability of TP53 protein] which results in increased expression of CDKN1A mRNA | increases^expression|increases^stability | 20536192 |
66 | 66 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | ACHE | 43 | protein | Mus musculus | 10,090 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide results in decreased activity of ACHE protein | decreases^activity | 15525694 |
67 | 67 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | ACTA1 | 58 | protein | Bos taurus | 9,913 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to ACTA1 protein | affects^binding | 19539807 |
68 | 68 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | ALB | 213 | protein | Mus musculus | 10,090 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to ALB protein | affects^binding | 15525694 |
69 | 69 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | ATP5F1B | 506 | protein | Mus musculus | 10,090 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to ATP5F1B protein | affects^binding | 19539807 |
70 | 70 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | AZGP1 | 563 | protein | Homo sapiens | 9,606 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to AZGP1 protein | affects^binding | 19539807 |
71 | 71 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | BCHE | 590 | protein | Mus musculus | 10,090 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide results in decreased activity of BCHE protein | decreases^activity | 15525694 |
72 | 72 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | CES1C | 13,884 | protein | Mus musculus | 10,090 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to CES1C protein | affects^binding | 15525694 |
73 | 73 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | CTRB2 | 440,387 | protein | Bos taurus | 9,913 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to CTRB2 protein | affects^binding | 19539807 |
74 | 74 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | KIF3C | 3,797 | protein | Homo sapiens | 9,606 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to KIF3C protein | affects^binding | 19539807 |
75 | 75 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | KRT1 | 3,848 | protein | Homo sapiens | 9,606 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to KRT1 protein | affects^binding | 19539807 |
76 | 76 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | SLC25A4 | 291 | protein | Mus musculus | 10,090 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to SLC25A4 protein | affects^binding | 19539807 |
77 | 77 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | TF | 7,018 | protein | Homo sapiens | 9,606 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to TF protein | affects^binding | 18930948 |
78 | 78 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide | C403065 | null | TRF | 22,041 | protein | Mus musculus | 10,090 | 10-(fluoroethoxyphosphinyl)-N-(biotinamidopentyl)decanamide binds to TRF protein | affects^binding | 18930948 |
79 | 79 | 10-formyltetrahydropteroylglutamic acid | C010161 | null | ALDH1L2 | 160,428 | protein | Homo sapiens | 9,606 | ALDH1L2 protein results in increased metabolism of 10-formyltetrahydropteroylglutamic acid | increases^metabolic processing | 21238436 |
80 | 80 | 10H-3,6-diazaphenothiazine | C000627785 | null | CASP2 | 835 | protein | Rattus norvegicus | 10,116 | 10H-3,6-diazaphenothiazine results in increased activity of CASP2 protein | increases^activity | 32619082 |
81 | 81 | 10H-3,6-diazaphenothiazine | C000627785 | null | CASP6 | 839 | protein | Rattus norvegicus | 10,116 | 10H-3,6-diazaphenothiazine results in increased activity of CASP6 protein | increases^activity | 32619082 |
82 | 82 | 10H-3,6-diazaphenothiazine | C000627785 | null | CASP8 | 841 | protein | Rattus norvegicus | 10,116 | 10H-3,6-diazaphenothiazine results in increased activity of CASP8 protein | increases^activity | 32619082 |
83 | 83 | 10H-3,6-diazaphenothiazine | C000627785 | null | CASP9 | 842 | protein | Rattus norvegicus | 10,116 | 10H-3,6-diazaphenothiazine results in increased activity of CASP9 protein | increases^activity | 32619082 |
84 | 84 | 10-hydroxycamptothecin | C028098 | null | BCL2 | 596 | protein | Homo sapiens | 9,606 | BCL2 protein affects the susceptibility to 10-hydroxycamptothecin | affects^response to substance | 16603448 |
85 | 85 | 10-hydroxycamptothecin | C028098 | null | BCL2L1 | 598 | protein | Homo sapiens | 9,606 | BCL2L1 protein affects the susceptibility to 10-hydroxycamptothecin | affects^response to substance | 17033717 |
86 | 86 | 10-hydroxycamptothecin | C028098 | null | CASP3 | 836 | protein | Homo sapiens | 9,606 | [10-hydroxycamptothecin co-treated with Fluorouracil co-treated with Leucovorin] results in increased activity of CASP3 protein | affects^cotreatment|increases^activity | 12934351 |
87 | 87 | 10-hydroxycamptothecin | C028098 | null | DDIT3 | 1,649 | mRNA | Cricetinae | 10,026 | 10-hydroxycamptothecin results in increased expression of DDIT3 mRNA | increases^expression | 19013231 |
88 | 88 | 10-hydroxycamptothecin | C028098 | null | MDM2 | 4,193 | protein | Homo sapiens | 9,606 | MDM2 protein affects the susceptibility to 10-hydroxycamptothecin | affects^response to substance | 13130078 |
89 | 89 | 10-hydroxynortriptyline | C013567 | null | CYP2D6 | 1,565 | gene | Homo sapiens | 9,606 | CYP2D6 gene mutant form results in increased abundance of 10-hydroxynortriptyline | increases^abundance | 11673748 |
90 | 90 | 10-hydroxynortriptyline | C013567 | null | CYP2D6 | 1,565 | gene | Homo sapiens | 9,606 | Paroxetine inhibits the reaction [CYP2D6 gene mutant form results in increased abundance of 10-hydroxynortriptyline] | decreases^reaction|increases^abundance | 11673748 |
91 | 91 | 10-hydroxynortriptyline | C013567 | null | CYP2D6 | 1,565 | null | null | null | CYP2D6 affects the chemical synthesis of 10-hydroxynortriptyline | affects^chemical synthesis | 18359183 |
92 | 92 | 10-hydroxywarfarin | C065719 | null | CYP2C9 | 1,559 | protein | Homo sapiens | 9,606 | 10-hydroxywarfarin binds to and results in decreased activity of CYP2C9 protein | affects^binding|decreases^activity | 20429590 |
93 | 93 | 10-hydroxywarfarin | C065719 | null | CYP2C9 | 1,559 | mRNA | Homo sapiens | 9,606 | [10-hydroxywarfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP2C9 mRNA | affects^binding|increases^activity|increases^expression | 20735727 |
94 | 94 | 10-hydroxywarfarin | C065719 | null | CYP2C9 | 1,559 | protein | Homo sapiens | 9,606 | 10-hydroxywarfarin inhibits the reaction [[CYP2C9 protein results in increased hydroxylation of Warfarin] which results in increased chemical synthesis of 7-hydroxywarfarin] | decreases^reaction|increases^chemical synthesis|increases^hydroxylation | 20429590 |
95 | 95 | 10-hydroxywarfarin | C065719 | null | CYP2C9 | 1,559 | gene | Homo sapiens | 9,606 | [CYP2C9 gene polymorphism affects the metabolism of Warfarin] which affects the abundance of 10-hydroxywarfarin | affects^abundance|affects^metabolic processing | 27539372 |
96 | 96 | 10-hydroxywarfarin | C065719 | null | CYP3A4 | 1,576 | mRNA | Homo sapiens | 9,606 | [10-hydroxywarfarin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA | affects^binding|increases^activity|increases^expression | 20735727 |
97 | 97 | 10-hydroxywarfarin | C065719 | null | CYP3A4 | 1,576 | protein | Homo sapiens | 9,606 | CYP3A4 protein affects the chemical synthesis of 10-hydroxywarfarin | affects^chemical synthesis | 16035367 |
98 | 98 | 10-hydroxywarfarin | C065719 | null | CYP3A4 | 1,576 | protein | null | null | CYP3A4 protein results in increased chemical synthesis of 10-hydroxywarfarin | increases^chemical synthesis | 20429590 |
99 | 99 | 10-hydroxywarfarin | C065719 | null | NR1I2 | 8,856 | protein | Homo sapiens | 9,606 | 10-hydroxywarfarin binds to and results in increased activity of NR1I2 protein | affects^binding|increases^activity | 20735727 |
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