| "reason": "'domain' is a required property\n\nFailed validating 'required' in schema:\n {'$schema': 'https://json-schema.org/draft/2020-12/schema',\n 'type': 'object',\n 'required': ['id',\n 'domain',\n 'hard_case_family',\n 'query',\n 'contexts',\n 'context_sources',\n 'candidate_answers',\n 'accepted_status',\n 'scores',\n 'external_citations',\n 'retrieval_challenge',\n 'ground_truth_type',\n 'oracle',\n 'content_license',\n 'provenance',\n 'group_id',\n 'split'],\n 'additionalProperties': False,\n 'properties': {'id': {'type': ['string'], 'minLength': 10},\n 'domain': {'type': ['string']},\n 'hard_case_family': {'type': ['array']},\n 'query': {'type': ['string']},\n 'contexts': {'type': ['array']},\n 'context_sources': {'type': ['array']},\n 'candidate_answers': {'type': ['array']},\n 'accepted_status': {'type': ['null', 'object']},\n 'scores': {'type': ['array', 'null']},\n 'external_citations': {'type': ['array']},\n 'retrieval_challenge': {'type': ['string']},\n 'ground_truth_type': {'type': ['string']},\n 'oracle': {'type': ['object']},\n 'content_license': {'type': ['string']},\n 'provenance': {'type': ['object'],\n 'required': ['source_dataset',\n 'source_record_id',\n 'source_record_sha256',\n 'source_license',\n 'transformation'],\n 'properties': {'source_record_sha256': {'type': 'string',\n 'pattern': '^[a-f0-9]{64}$'}}},\n 'group_id': {'type': ['string'],\n 'pattern': '^[a-f0-9]{64}$'},\n 'split': {'enum': ['train',\n 'validation',\n 'test',\n 'holdout'],\n 'type': ['string']}}}\n\nOn instance:\n {'accepted_status': {'accepted_answer_id': 112863,\n 'scientific_correctness_verified': False},\n 'candidate_answers': [{'answer_html': '<p>I searched for this '\n 'question and obtained the '\n 'answer, which I will expand '\n 'on.</p>\\n'\n '<p>There is a mechanism called '\n \"'allele exclusion' (allelic \"\n 'exclusion),\\n'\n 'which means that when one of a '\n 'pair of immunoglobulin/TCR '\n 'genes is successfully '\n 'reconstituted and\\n'\n 'becomes a functional gene, the '\n 'other one ceases to function.\\n'\n 'Eventually, only one or the '\n 'other is expressed.</p>\\n'\n '<p>For more information, '\n 'search for "allele '\n 'exclusion" or '\n '"allelic '\n 'exclusion".\\n'\n '<a '\n 'href=\"https://en.wikipedia.org/wiki/Allelic_exclusion\" '\n 'rel=\"nofollow '\n 'noreferrer\">https://en.wikipedia.org/wiki/Allelic_exclusion</a>\\n'\n '<a '\n 'href=\"https://pubmed.ncbi.nlm.nih.gov/12707333/\" '\n 'rel=\"nofollow '\n 'noreferrer\">https://pubmed.ncbi.nlm.nih.gov/12707333/</a></p>\\n',\n 'answer_id': 112863,\n 'answer_text': 'I searched for this question '\n 'and obtained the answer, which '\n 'I will expand on.\\n'\n '\\n'\n '\\n'\n '\\n'\n '\\n'\n 'There is a mechanism called '\n \"'allele exclusion' (allelic \"\n 'exclusion),\\n'\n 'which means that when one of a '\n 'pair of immunoglobulin/TCR '\n 'genes is successfully '\n 'reconstituted and\\n'\n 'becomes a functional gene, the '\n 'other one ceases to function.\\n'\n 'Eventually, only one or the '\n 'other is expressed.\\n'\n '\\n'\n '\\n'\n '\\n'\n '\\n'\n 'For more information, search '\n 'for \"allele exclusion\" or '\n '\"allelic exclusion\".\\n'\n 'https://en.wikipedia.org/wiki/Allelic_exclusion '\n '(https://en.wikipedia.org/wiki/Allelic_exclusion)\\n'\n 'https://pubmed.ncbi.nlm.nih.gov/12707333/ '\n '(https://pubmed.ncbi.nlm.nih.gov/12707333/)',\n 'answer_url': 'https://biology.stackexchange.com/a/112863',\n 'author': 'Blue Various',\n 'author_url': 'https://biology.stackexchange.com/users/53374/blue-various',\n 'content_license': 'CC BY-SA 4.0',\n 'created_at': '2023-08-24T02:54:16+00:00',\n 'is_accepted': True,\n 'provenance': {'attribution_required': True,\n 'collected_at': '2026-10-01T03:03:38.885561+00:00',\n 'license': 'CC BY-SA 4.0',\n 'license_url': 'https://creativecommons.org/licenses/by-sa/4.0/',\n 'raw_file': 'raw/codex_api_v1/a145de97eabc007745b45919875489a41261075cbdf33d916d9640ba4ad0bd35_0.json',\n 'raw_sha256': 'e7d8d4315eef8e039a452d2811869cbe305575c6ff8a6bef8f80d6dfb58c5bfd',\n 'source_api': 'Stack Exchange '\n 'API 2.3',\n 'source_url': 'https://api.stackexchange.com/2.3/questions/112982;112980;112979;112977;112972;112967;112962;112956;112952;112948;112941;112938;112937;112936;112927;112925;112923;112919;112909;112905;112904;112898;112895;112893;112884;112881;112880;112879;112873;112872;112870;112869;112867;112850;112849;112848;112841;112835;112831;112824;112818;112811;112808;112807;112790;112789;112785;112777;112773;112770;112762;112759;112757;112756;112746;112739;112738;112737;112731;112705;112703;112700;112699;112698;112693;112691;112687;112685;112677;112671;112667;112663;112659;112653;112647;112646;112645;112636;112625;112621;112615;112614;112613;112610;112598;112593;112592;112586;112580;112575;112574;112564;112558;112552;112550;112549;112544;112539;112535;112531/answers?filter=withbody&order=asc&page=1&pagesize=100&site=biology&sort=creation',\n 'transformation': 'API HTML '\n 'retained; '\n 'mechanical '\n 'HTML-to-text; '\n 'no LLM '\n 'rewriting'},\n 'question_id': 112544,\n 'revision_attribution': [{'content_license': 'CC '\n 'BY-SA '\n '4.0',\n 'contributor': {'display_name': 'Blue '\n 'Various',\n 'profile_url': 'https://biology.stackexchange.com/users/53374/blue-various',\n 'user_type': 'registered'},\n 'created_at': '2023-08-24T02:54:16+00:00',\n 'raw_file': 'raw/codex_api_v1/9b8fea4e5df4051aa25c1aa90b42eca7481ee703f92ba25aeabed3d0b53e7a04_1790824026598483100_0.json',\n 'raw_sha256': 'f252fc1b154815b8794116efb3b685202eda8dddb2cd870ae32ee5e82716c300',\n 'revision_guid': '714A675C-B6D7-4911-8817-CB88ECF3A1EA',\n 'revision_number': 1,\n 'revision_type': 'single_user',\n 'revision_url': 'https://biology.stackexchange.com/revisions/714A675C-B6D7-4911-8817-CB88ECF3A1EA/view-source'}],\n 'score': 0}],\n 'content_license': 'CC BY-SA 4.0',\n 'context_sources': [{'author': 'Blue Various',\n 'author_url': 'https://biology.stackexchange.com/users/53374/blue-various',\n 'content_license': 'CC BY-SA 4.0',\n 'context_id': 'question',\n 'revision_attribution': [{'content_license': 'CC '\n 'BY-SA '\n '4.0',\n 'contributor': {'display_name': 'Blue '\n 'Various',\n 'profile_url': 'https://biology.stackexchange.com/users/53374/blue-various',\n 'user_type': 'registered'},\n 'created_at': '2023-07-12T11:27:53+00:00',\n 'raw_file': 'raw/codex_api_v1/0afc9875e3b11976af222c2a36168e832bf7a8ace8bb569f2957b7cb1cb2e6b5_1790824010273431600_0.json',\n 'raw_sha256': '72bb3c5d2eeea42ab0779afb27cfa435fb887415c83a3353ac873540e2722b3c',\n 'revision_guid': '41E24E86-0291-4FC0-A6D9-8BEEB07F492A',\n 'revision_number': 1,\n 'revision_type': 'single_user',\n 'revision_url': 'https://biology.stackexchange.com/revisions/41E24E86-0291-4FC0-A6D9-8BEEB07F492A/view-source'}],\n 'url': 'https://biology.stackexchange.com/questions/112544/why-dont-each-of-t-and-b-cells-make-two-different-tcrs-antibodies-except-for-t'},\n {'author': 'Blue Various',\n 'author_url': 'https://biology.stackexchange.com/users/53374/blue-various',\n 'content_license': 'CC BY-SA 4.0',\n 'context_id': '112863',\n 'revision_attribution': [{'content_license': 'CC '\n 'BY-SA '\n '4.0',\n 'contributor': {'display_name': 'Blue '\n 'Various',\n 'profile_url': 'https://biology.stackexchange.com/users/53374/blue-various',\n 'user_type': 'registered'},\n 'created_at': '2023-08-24T02:54:16+00:00',\n 'raw_file': 'raw/codex_api_v1/9b8fea4e5df4051aa25c1aa90b42eca7481ee703f92ba25aeabed3d0b53e7a04_1790824026598483100_0.json',\n 'raw_sha256': 'f252fc1b154815b8794116efb3b685202eda8dddb2cd870ae32ee5e82716c300',\n 'revision_guid': '714A675C-B6D7-4911-8817-CB88ECF3A1EA',\n 'revision_number': 1,\n 'revision_type': 'single_user',\n 'revision_url': 'https://biology.stackexchange.com/revisions/714A675C-B6D7-4911-8817-CB88ECF3A1EA/view-source'}],\n 'url': 'https://biology.stackexchange.com/a/112863'}],\n 'contexts': [{'context_id': 'question',\n 'html': '<p>I have not been able to find any literature '\n 'that clearly states this, but if I understand '\n 'correctly, T and B cells are diploid.</p>\\n'\n '<p>If so, there are two sets of genomes, and '\n 'if both are TCR/VDJ reconstituted, it would '\n 'seem that one cell would have two different '\n 'TCR/antibodies. In other words, there will be '\n 'a TCR/antibody produced by TCR/VDJ '\n 'rearrangement of a patternal chromosome and a '\n 'TCR/antibody produced by TCR/VDJ rearrangement '\n 'of a maternal chromosome.\\n'\n \"Why doesn't that happen?</p>\\n\",\n 'text': 'I have not been able to find any literature '\n 'that clearly states this, but if I understand '\n 'correctly, T and B cells are diploid.\\n'\n '\\n'\n '\\n'\n '\\n'\n '\\n'\n 'If so, there are two sets of genomes, and if '\n 'both are TCR/VDJ reconstituted, it would seem '\n 'that one cell would have two different '\n 'TCR/antibodies. In other words, there will be '\n 'a TCR/antibody produced by TCR/VDJ '\n 'rearrangement of a patternal chromosome and a '\n 'TCR/antibody produced by TCR/VDJ rearrangement '\n 'of a maternal chromosome.\\n'\n \"Why doesn't that happen?\"},\n {'context_id': '112863',\n 'html': '<p>I searched for this question and obtained '\n 'the answer, which I will expand on.</p>\\n'\n \"<p>There is a mechanism called 'allele \"\n \"exclusion' (allelic exclusion),\\n\"\n 'which means that when one of a pair of '\n 'immunoglobulin/TCR genes is successfully '\n 'reconstituted and\\n'\n 'becomes a functional gene, the other one '\n 'ceases to function.\\n'\n 'Eventually, only one or the other is '\n 'expressed.</p>\\n'\n '<p>For more information, search for '\n '"allele exclusion" or "allelic '\n 'exclusion".\\n'\n '<a '\n 'href=\"https://en.wikipedia.org/wiki/Allelic_exclusion\" '\n 'rel=\"nofollow '\n 'noreferrer\">https://en.wikipedia.org/wiki/Allelic_exclusion</a>\\n'\n '<a '\n 'href=\"https://pubmed.ncbi.nlm.nih.gov/12707333/\" '\n 'rel=\"nofollow '\n 'noreferrer\">https://pubmed.ncbi.nlm.nih.gov/12707333/</a></p>\\n',\n 'text': 'I searched for this question and obtained the '\n 'answer, which I will expand on.\\n'\n '\\n'\n '\\n'\n '\\n'\n '\\n'\n \"There is a mechanism called 'allele exclusion' \"\n '(allelic exclusion),\\n'\n 'which means that when one of a pair of '\n 'immunoglobulin/TCR genes is successfully '\n 'reconstituted and\\n'\n 'becomes a functional gene, the other one '\n 'ceases to function.\\n'\n 'Eventually, only one or the other is '\n 'expressed.\\n'\n '\\n'\n '\\n'\n '\\n'\n '\\n'\n 'For more information, search for \"allele '\n 'exclusion\" or \"allelic exclusion\".\\n'\n 'https://en.wikipedia.org/wiki/Allelic_exclusion '\n '(https://en.wikipedia.org/wiki/Allelic_exclusion)\\n'\n 'https://pubmed.ncbi.nlm.nih.gov/12707333/ '\n '(https://pubmed.ncbi.nlm.nih.gov/12707333/)'}],\n 'external_citations': ['https://en.wikipedia.org/wiki/Allelic_exclusion',\n 'https://pubmed.ncbi.nlm.nih.gov/12707333/'],\n 'ground_truth_type': 'metadata_grounded',\n 'group_id': '9ce45c6f813999e95d213c69804fba40e139b51690ed16592f4089dd7137538b',\n 'hard_case_family': ['multiple_sources'],\n 'id': 'RHM-e9015ba6be60f48da28e32cd',\n 'oracle': {'canonical_answer': None,\n 'rules_version': 'scientific_metadata_v3'},\n 'provenance': {'original_provenance': {'attribution_required': True,\n 'collected_at': '2026-10-01T03:03:12.794960+00:00',\n 'license': 'CC BY-SA 4.0',\n 'license_url': 'https://creativecommons.org/licenses/by-sa/4.0/',\n 'raw_file': 'raw/codex_api_v1/01e5186067e30dc1b8d7a145670ab7edd6b017797b271a481af8b7b7f55f13c2_0.json',\n 'raw_sha256': '6c3960de7e1d3d7920bb88d02e2184614c219b391f39d9bddc2a582fdc9a71e7',\n 'source_api': 'Stack Exchange '\n 'API 2.3',\n 'source_url': 'https://api.stackexchange.com/2.3/search/advanced?answers=1&filter=withbody&order=desc&page=10&pagesize=100&site=biology&sort=creation',\n 'transformation': 'API HTML '\n 'retained; '\n 'mechanical '\n 'HTML-to-text; '\n 'no LLM '\n 'rewriting'},\n 'revision_attribution': [{'content_license': 'CC BY-SA '\n '4.0',\n 'contributor': {'display_name': 'Blue '\n 'Various',\n 'profile_url': 'https://biology.stackexchange.com/users/53374/blue-various',\n 'user_type': 'registered'},\n 'created_at': '2023-07-12T11:27:53+00:00',\n 'raw_file': 'raw/codex_api_v1/0afc9875e3b11976af222c2a36168e832bf7a8ace8bb569f2957b7cb1cb2e6b5_1790824010273431600_0.json',\n 'raw_sha256': '72bb3c5d2eeea42ab0779afb27cfa435fb887415c83a3353ac873540e2722b3c',\n 'revision_guid': '41E24E86-0291-4FC0-A6D9-8BEEB07F492A',\n 'revision_number': 1,\n 'revision_type': 'single_user',\n 'revision_url': 'https://biology.stackexchange.com/revisions/41E24E86-0291-4FC0-A6D9-8BEEB07F492A/view-source'}],\n 'source_commit': '049a9227f533c13bbc10d1a38c271e055da0ed6e',\n 'source_data_file': 'dataset.jsonl',\n 'source_dataset': 'RegalFire/Scientific-Biology-QA',\n 'source_license': 'CC BY-SA 4.0',\n 'source_record_id': '112544',\n 'source_record_sha256': 'ade2e15fa28e54994095dfa72fa4078b53e4fffe4285ec4897a7e44e96a2b168',\n 'source_url': 'https://biology.stackexchange.com/questions/112544/why-dont-each-of-t-and-b-cells-make-two-different-tcrs-antibodies-except-for-t',\n 'transformation': 'RegalFire V3 deterministic '\n 'transformation; no LLM truth '\n 'labels'},\n 'query': \"Why don't each of T and B cells make two different \"\n 'TCRs/antibodies, except for the class switch?\\n'\n 'I have not been able to find any literature that clearly '\n 'states this, but if I understand correctly, T and B cells '\n 'are diploid.\\n'\n '\\n'\n '\\n'\n '\\n'\n '\\n'\n 'If so, there are two sets of genomes, and if both are '\n 'TCR/VDJ reconstituted, it would seem that one cell would '\n 'have two different TCR/antibodies. In other words, there '\n 'will be a TCR/antibody produced by TCR/VDJ rearrangement of '\n 'a patternal chromosome and a TCR/antibody produced by '\n 'TCR/VDJ rearrangement of a maternal chromosome.\\n'\n \"Why doesn't that happen?\",\n 'retrieval_challenge': 'Metadata-grounded challenge flags; semantic '\n 'conflict and scientific correctness are not '\n 'asserted',\n 'scores': [{'answer_id': 112863, 'score': 0}],\n 'split': 'train'}"
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