Dataset Preview
The full dataset viewer is not available (click to read why). Only showing a preview of the rows.
The dataset generation failed because of a cast error
Error code: DatasetGenerationCastError
Exception: DatasetGenerationCastError
Message: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 15 new columns ({'strict_minimum_count_eligible_only', 'gene_symbol', 'strict_n00', 'n_total_usable_genotypes_and_X', 'note', 'C1_beta', 'strict_n01', 'strict_n11', 'C1_q_global_BY', 'count_audit_status', 'n_00_and_01_ge5', 'strict_n_lineages_with_all_4_ge2', 'strict_n10', 'gene', 'strict_n_models_after_lineage_filter'}) and 2 missing columns ({'n_models_total_in_partition', 'n_genotypes_observed'}).
This happened while the csv dataset builder was generating data using
hf://datasets/Tanvir106/final_comutation/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/02_83_Association_TargetX_CRISPR_Counts.csv (at revision d043ad7f9de57499af416870023c69a41ac67cfd), ['hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/01_42_UniquePair_GenotypeCounts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/02_83_Association_TargetX_CRISPR_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/03_42_Pair_ByLineage_GenotypeCounts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/04_83_Association_TargetX_ByLineage_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/05_83_Association_Discovery_Count_Overview.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_010441_UTC/01_Targeted_12_FourGroup_AxB_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_010441_UTC/02_All_83_Selection_And_Results.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_011936_UTC/01_Targeted_12_FourGroup_AxB_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_011936_UTC/02_All_83_Selection_And_Results.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_internal_holdout.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_original_model_partition.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_refit_details.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_refit_summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Functional_Annotations/Optional_Annotation_Errors.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Functional_Annotations/STRING_Protein_Association_Network.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Functional_Annotations/UniProt_GO_Gene_Function.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/C1_Primary_PanCancer_BY_05.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/across_lineage_meta_analysis.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/all_context_summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/all_discovery_signals.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/context_manifest.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/context_manifest_with_multiplicity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/dataset_manifest.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/discovery_signals_with_essentiality.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/gene_candidate_registry.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/hypothesis_catalogue.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/internal_holdout_confirmation.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/molecular_support.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/pathways/ora_all_contexts.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/pathways/preranked_gsea_all_contexts.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/provider_lock_audit.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/qc/C2_Methods.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/qc/exhaustive_nonestimable_counts_by_reason.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/qc/representative_sparse_pair_examples.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/signal_sensitivity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/00_C2_Reconstructed_Original_Model_Partition.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/00_Existing_T3_Original_Refit_Robustness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/01_C2_Evidence_Flow.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/02_C2_Refit_Prioritization_Rule.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/03_C2_All546_Refit_Prioritization.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/04_C2_Refit_Summary_All546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/05_C2_IndividualModel_LOO_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/06A_C2_Model_Lineage_Combined_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/06_C2_Lineage_LOO_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/07_C2_All_Deletion_Refits.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/08_C2_Internal_Holdout_All546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/09_C2_Holdout_Sample_Deficits_And_CRISPR_Missingness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/10_C2_ThirdGene_Holdout_75.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/11_C2_CommonEssentiality_Crosswalk_83.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/12_C2_Covariate_Sensitivity_83x4.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/13_C2_Covariate_Sensitivity_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/14_C2_AlternativeSplit_HypothesisFeasibility_101seeds.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/15_C2_AlternativeSplit_SeedSummary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/16_C2_AlternativeSplit_SkippedSeeds.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/17_C2_Table_Crosswalk.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/18_C2_Figure_Crosswalk.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/26_C2_Figure_Crosswalk.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_C2_All546_Lineage_Overlap_Diagnostics.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_Discovery_Signals_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_Original_C3_FourGroup_Coverage_T6.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_T3_Original_Refit_Robustness_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Table_Figure_Index.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_00_C1_BY83_Parent_Discovery.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_00_Original_Holdout_546_Unchanged.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_01_Holdout_Status_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_02_Confirmed3_Discovery_vs_Holdout.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_03B_C1_BY83_Holdout_Status_By_TargetClass.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_03_C1_BY83_PostHoc_Holdout_Status.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_04_Holdout_TargetSpecific_Deficits_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_05_Holdout_Deficit_Diagnostic_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_06_Holdout_Precision_SampleSize_Planning_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_07_C2_Refit_Robustness_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_08_C2_Refit_Robustness_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_09_C1_BY83_FourGroup_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_10_FourGroup_Feasibility_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_11_Strict12_AxB_Interaction.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_12_Expanded34_LineageAdjusted_AxB.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_13_Expanded34_NoLineageCovariate_AxB.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_14_Strict12_vs_Expanded34_Comparison.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_15_Interaction_Model_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_16_All_80_Interaction_Model_Fits.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_17_Holdout_Exploratory_Sensitivity_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_18_C1_BY83_PostHoc_Holdout_Sensitivity_249.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_19_Holdout_Sensitivity_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Figure_Index.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Methods_and_Evidence/Experiment_Claim_to_Evidence_Registry.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST1_Expression_Pathway_Activity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST2_Pooled_Exploratory_AxB.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST3_Four_Genotype_Raw_Arm_Coverage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST4_Four_Genotype_By_Lineage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Table_Index.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T10_TCGA_Patient_CoMutation_Prevalence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T11_Integrated_Candidate_Evidence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T12_Noncausal_Interpretation_And_Failed_Evidence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T1_Raw_Source_And_Integrity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T2_Primary_PanCancer_C1_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T3_Original_Refit_Robustness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T4_Reactome_ORA_GSEA.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T5_Expression_CN_Molecular.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T6_C3_Four_Group_Original_Coverage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T7_PRISM_Conditional_Drug_Response.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T8_PRISM_Strict_AxB_Interaction.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T9_PRISM_AB_vs_Bonly.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/01_Freshly_Computed_C1_BY_05.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/02_Target_Drug_Arm_Coverage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/03_C1_Target_Mapping_Completeness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/04_Fresh_Genotype_Arm_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/02_Oncogenic_Pathway_Activity/Oncogenic_Pathway_A_B_Comparison_HC3.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/03_Indirect_Pathway_Evidence/Exploratory_Indirect_Pathway_Concordance.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/04_Druggability_Prioritization/C1_Compound_Target_Clinical_Phase_Annotations.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/05_TCGA_CoMutation_Prevalence/Selected_TCGA_Study_Patient_Mutation_Cooccurrence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/06_PRISM_Drug_Response_Statistics/PRISM_Leave_One_Lineage_Out_Robustness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/06_PRISM_Drug_Response_Statistics/PRISM_drug_response_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/09_Integrated_Results/All_C1_Drug_Conditional_and_Interaction_Evidence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/09_Integrated_Results/C1_Therapeutic_Integrated_Priority_Table.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_AB_vs_Bonly_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Arm_Counts_By_Lineage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Exploratory_Pooled_Interaction_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Raw_Arm_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Strict_Interaction_HC3_BH_BY.csv']
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)
Traceback: Traceback (most recent call last):
File "/usr/local/lib/python3.14/site-packages/datasets/builder.py", line 1856, in _prepare_split_single
writer.write_table(table)
~~~~~~~~~~~~~~~~~~^^^^^^^
File "/usr/local/lib/python3.14/site-packages/datasets/arrow_writer.py", line 811, in write_table
self._write_table(pa_table, writer_batch_size=writer_batch_size)
~~~~~~~~~~~~~~~~~^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.14/site-packages/datasets/arrow_writer.py", line 822, in _write_table
pa_table = table_cast(pa_table, self._schema)
File "/usr/local/lib/python3.14/site-packages/datasets/table.py", line 2381, in table_cast
return cast_table_to_schema(table, schema)
File "/usr/local/lib/python3.14/site-packages/datasets/table.py", line 2309, in cast_table_to_schema
raise CastError(
...<3 lines>...
)
datasets.table.CastError: Couldn't cast
A: string
B: string
A_symbol: string
B_symbol: string
n_C1_associations_for_pair: int64
gene: string
gene_symbol: string
C1_beta: double
C1_q_global_BY: double
partition: string
n00: int64
n01: int64
n10: int64
n11: int64
n_total_usable_genotypes_and_X: int64
n_00_and_01_ge5: bool
all_four_groups_ge5: bool
strict_n_lineages_with_all_4_ge2: int64
strict_n00: int64
strict_n01: int64
strict_n10: int64
strict_n11: int64
strict_n_models_after_lineage_filter: int64
strict_minimum_count_eligible_only: bool
count_audit_status: string
note: string
-- schema metadata --
pandas: '{"index_columns": [{"kind": "range", "name": null, "start": 0, "' + 3488
to
{'A': Value('string'), 'B': Value('string'), 'A_symbol': Value('string'), 'B_symbol': Value('string'), 'n_C1_associations_for_pair': Value('int64'), 'partition': Value('string'), 'n00': Value('int64'), 'n01': Value('int64'), 'n10': Value('int64'), 'n11': Value('int64'), 'n_genotypes_observed': Value('int64'), 'all_four_groups_ge5': Value('bool'), 'n_models_total_in_partition': Value('int64')}
because column names don't match
During handling of the above exception, another exception occurred:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1379, in compute_config_parquet_and_info_response
parquet_operations, partial, estimated_dataset_info = stream_convert_to_parquet(
~~~~~~~~~~~~~~~~~~~~~~~~~^
builder, max_dataset_size_bytes=max_dataset_size_bytes
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
)
^
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 956, in stream_convert_to_parquet
builder._prepare_split(split_generator=splits_generators[split], file_format="parquet")
~~~~~~~~~~~~~~~~~~~~~~^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
File "/usr/local/lib/python3.14/site-packages/datasets/builder.py", line 1702, in _prepare_split
for job_id, done, content in self._prepare_split_single(
~~~~~~~~~~~~~~~~~~~~~~~~~~^
gen_kwargs=gen_kwargs, job_id=job_id, **_prepare_split_args
^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
):
^
File "/usr/local/lib/python3.14/site-packages/datasets/builder.py", line 1858, in _prepare_split_single
raise DatasetGenerationCastError.from_cast_error(
...<4 lines>...
)
datasets.exceptions.DatasetGenerationCastError: An error occurred while generating the dataset
All the data files must have the same columns, but at some point there are 15 new columns ({'strict_minimum_count_eligible_only', 'gene_symbol', 'strict_n00', 'n_total_usable_genotypes_and_X', 'note', 'C1_beta', 'strict_n01', 'strict_n11', 'C1_q_global_BY', 'count_audit_status', 'n_00_and_01_ge5', 'strict_n_lineages_with_all_4_ge2', 'strict_n10', 'gene', 'strict_n_models_after_lineage_filter'}) and 2 missing columns ({'n_models_total_in_partition', 'n_genotypes_observed'}).
This happened while the csv dataset builder was generating data using
hf://datasets/Tanvir106/final_comutation/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/02_83_Association_TargetX_CRISPR_Counts.csv (at revision d043ad7f9de57499af416870023c69a41ac67cfd), ['hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/01_42_UniquePair_GenotypeCounts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/02_83_Association_TargetX_CRISPR_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/03_42_Pair_ByLineage_GenotypeCounts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/04_83_Association_TargetX_ByLineage_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_FourGroup_Count_Feasibility/20261109_004035_UTC/05_83_Association_Discovery_Count_Overview.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_010441_UTC/01_Targeted_12_FourGroup_AxB_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_010441_UTC/02_All_83_Selection_And_Results.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_011936_UTC/01_Targeted_12_FourGroup_AxB_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C1_83_Targeted_FourGroup_Interaction/20261109_011936_UTC/02_All_83_Selection_And_Results.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_internal_holdout.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_original_model_partition.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_refit_details.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/experimental_runs/C2_Expanded_Analysis/_checkpoints/20261112_003436_708878_UTC/C2_refit_summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Functional_Annotations/Optional_Annotation_Errors.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Functional_Annotations/STRING_Protein_Association_Network.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Functional_Annotations/UniProt_GO_Gene_Function.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/C1_Primary_PanCancer_BY_05.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/across_lineage_meta_analysis.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/all_context_summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/all_discovery_signals.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/context_manifest.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/context_manifest_with_multiplicity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/dataset_manifest.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/discovery_signals_with_essentiality.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/gene_candidate_registry.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/hypothesis_catalogue.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/internal_holdout_confirmation.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/molecular_support.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/pathways/ora_all_contexts.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/pathways/preranked_gsea_all_contexts.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/provider_lock_audit.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/qc/C2_Methods.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/qc/exhaustive_nonestimable_counts_by_reason.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/qc/representative_sparse_pair_examples.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Main_C1_C2/signal_sensitivity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/00_C2_Reconstructed_Original_Model_Partition.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/00_Existing_T3_Original_Refit_Robustness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/01_C2_Evidence_Flow.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/02_C2_Refit_Prioritization_Rule.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/03_C2_All546_Refit_Prioritization.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/04_C2_Refit_Summary_All546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/05_C2_IndividualModel_LOO_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/06A_C2_Model_Lineage_Combined_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/06_C2_Lineage_LOO_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/07_C2_All_Deletion_Refits.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/08_C2_Internal_Holdout_All546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/09_C2_Holdout_Sample_Deficits_And_CRISPR_Missingness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/10_C2_ThirdGene_Holdout_75.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/11_C2_CommonEssentiality_Crosswalk_83.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/12_C2_Covariate_Sensitivity_83x4.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/13_C2_Covariate_Sensitivity_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/14_C2_AlternativeSplit_HypothesisFeasibility_101seeds.csv.gz', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/15_C2_AlternativeSplit_SeedSummary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/16_C2_AlternativeSplit_SkippedSeeds.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/17_C2_Table_Crosswalk.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/18_C2_Figure_Crosswalk.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/C2_Expanded_Analysis/20261112_003436_708878_UTC/26_C2_Figure_Crosswalk.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_C2_All546_Lineage_Overlap_Diagnostics.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_Discovery_Signals_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_Original_C3_FourGroup_Coverage_T6.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Supplementary_Source_Tables/Source_T3_Original_Refit_Robustness_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Table_Figure_Index.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_00_C1_BY83_Parent_Discovery.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_00_Original_Holdout_546_Unchanged.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_01_Holdout_Status_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_02_Confirmed3_Discovery_vs_Holdout.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_03B_C1_BY83_Holdout_Status_By_TargetClass.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_03_C1_BY83_PostHoc_Holdout_Status.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_04_Holdout_TargetSpecific_Deficits_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_05_Holdout_Deficit_Diagnostic_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_06_Holdout_Precision_SampleSize_Planning_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_07_C2_Refit_Robustness_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_08_C2_Refit_Robustness_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_09_C1_BY83_FourGroup_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_10_FourGroup_Feasibility_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_11_Strict12_AxB_Interaction.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_12_Expanded34_LineageAdjusted_AxB.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_13_Expanded34_NoLineageCovariate_AxB.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_14_Strict12_vs_Expanded34_Comparison.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_15_Interaction_Model_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_16_All_80_Interaction_Model_Fits.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_17_Holdout_Exploratory_Sensitivity_546.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_18_C1_BY83_PostHoc_Holdout_Sensitivity_249.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Claim3_Underpowered_And_Interaction/20261111_232839_UTC/Tables/Table_C3_19_Holdout_Sensitivity_Summary.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Figure_Index.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Methods_and_Evidence/Experiment_Claim_to_Evidence_Registry.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST1_Expression_Pathway_Activity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST2_Pooled_Exploratory_AxB.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST3_Four_Genotype_Raw_Arm_Coverage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Supplementary/ST4_Four_Genotype_By_Lineage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Table_Index.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T10_TCGA_Patient_CoMutation_Prevalence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T11_Integrated_Candidate_Evidence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T12_Noncausal_Interpretation_And_Failed_Evidence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T1_Raw_Source_And_Integrity.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T2_Primary_PanCancer_C1_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T3_Original_Refit_Robustness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T4_Reactome_ORA_GSEA.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T5_Expression_CN_Molecular.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T6_C3_Four_Group_Original_Coverage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T7_PRISM_Conditional_Drug_Response.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T8_PRISM_Strict_AxB_Interaction.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Paper_Experiment_Section/Tables/T9_PRISM_AB_vs_Bonly.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/01_Freshly_Computed_C1_BY_05.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/02_Target_Drug_Arm_Coverage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/03_C1_Target_Mapping_Completeness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/01_C1_And_Coverage/04_Fresh_Genotype_Arm_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/02_Oncogenic_Pathway_Activity/Oncogenic_Pathway_A_B_Comparison_HC3.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/03_Indirect_Pathway_Evidence/Exploratory_Indirect_Pathway_Concordance.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/04_Druggability_Prioritization/C1_Compound_Target_Clinical_Phase_Annotations.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/05_TCGA_CoMutation_Prevalence/Selected_TCGA_Study_Patient_Mutation_Cooccurrence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/06_PRISM_Drug_Response_Statistics/PRISM_Leave_One_Lineage_Out_Robustness.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/06_PRISM_Drug_Response_Statistics/PRISM_drug_response_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/09_Integrated_Results/All_C1_Drug_Conditional_and_Interaction_Evidence.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/09_Integrated_Results/C1_Therapeutic_Integrated_Priority_Table.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_AB_vs_Bonly_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Arm_Counts_By_Lineage.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Exploratory_Pooled_Interaction_HC3_BH_BY.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Raw_Arm_Counts.csv', 'hf://datasets/Tanvir106/final_comutation@d043ad7f9de57499af416870023c69a41ac67cfd/results/Therapeutic/12_PRISM_Four_Group_Interaction/PRISM_Four_Group_Strict_Interaction_HC3_BH_BY.csv']
Please either edit the data files to have matching columns, or separate them into different configurations (see docs at https://hf.co/docs/hub/datasets-manual-configuration#multiple-configurations)Need help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
A string | B string | A_symbol string | B_symbol string | n_C1_associations_for_pair int64 | partition string | n00 int64 | n01 int64 | n10 int64 | n11 int64 | n_genotypes_observed int64 | all_four_groups_ge5 bool | n_models_total_in_partition int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENTREZ:1029 | ENTREZ:94025 | CDKN2A | MUC16 | 1 | all | 971 | 70 | 126 | 11 | 1,178 | true | 1,178 |
ENTREZ:1029 | ENTREZ:94025 | CDKN2A | MUC16 | 1 | discovery | 767 | 57 | 105 | 9 | 938 | true | 938 |
ENTREZ:1029 | ENTREZ:94025 | CDKN2A | MUC16 | 1 | holdout | 204 | 13 | 21 | 2 | 240 | false | 240 |
ENTREZ:324 | ENTREZ:10664 | APC | CTCF | 1 | all | 1,078 | 24 | 70 | 6 | 1,178 | true | 1,178 |
ENTREZ:324 | ENTREZ:10664 | APC | CTCF | 1 | discovery | 856 | 19 | 57 | 6 | 938 | true | 938 |
ENTREZ:324 | ENTREZ:10664 | APC | CTCF | 1 | holdout | 222 | 5 | 13 | 0 | 240 | false | 240 |
ENTREZ:324 | ENTREZ:55252 | APC | ASXL2 | 1 | all | 1,092 | 10 | 70 | 6 | 1,178 | true | 1,178 |
ENTREZ:324 | ENTREZ:55252 | APC | ASXL2 | 1 | discovery | 867 | 8 | 58 | 5 | 938 | true | 938 |
ENTREZ:324 | ENTREZ:55252 | APC | ASXL2 | 1 | holdout | 225 | 2 | 12 | 1 | 240 | false | 240 |
ENTREZ:324 | ENTREZ:7468 | APC | NSD2 | 1 | all | 1,084 | 18 | 70 | 6 | 1,178 | true | 1,178 |
ENTREZ:324 | ENTREZ:7468 | APC | NSD2 | 1 | discovery | 859 | 16 | 57 | 6 | 938 | true | 938 |
ENTREZ:324 | ENTREZ:7468 | APC | NSD2 | 1 | holdout | 225 | 2 | 13 | 0 | 240 | false | 240 |
ENTREZ:324 | ENTREZ:84159 | APC | ARID5B | 1 | all | 1,092 | 10 | 70 | 6 | 1,178 | true | 1,178 |
ENTREZ:324 | ENTREZ:84159 | APC | ARID5B | 1 | discovery | 868 | 7 | 57 | 6 | 938 | true | 938 |
ENTREZ:324 | ENTREZ:84159 | APC | ARID5B | 1 | holdout | 224 | 3 | 13 | 0 | 240 | false | 240 |
ENTREZ:324 | ENTREZ:9585 | APC | KIF20B | 1 | all | 1,090 | 12 | 71 | 5 | 1,178 | true | 1,178 |
ENTREZ:324 | ENTREZ:9585 | APC | KIF20B | 1 | discovery | 868 | 7 | 58 | 5 | 938 | true | 938 |
ENTREZ:324 | ENTREZ:9585 | APC | KIF20B | 1 | holdout | 222 | 5 | 13 | 0 | 240 | false | 240 |
ENTREZ:324 | ENTREZ:9699 | APC | RIMS2 | 1 | all | 1,081 | 21 | 67 | 9 | 1,178 | true | 1,178 |
ENTREZ:324 | ENTREZ:9699 | APC | RIMS2 | 1 | discovery | 860 | 15 | 56 | 7 | 938 | true | 938 |
ENTREZ:324 | ENTREZ:9699 | APC | RIMS2 | 1 | holdout | 221 | 6 | 11 | 2 | 240 | false | 240 |
ENTREZ:673 | ENTREZ:7157 | BRAF | TP53 | 1 | all | 359 | 721 | 54 | 44 | 1,178 | true | 1,178 |
ENTREZ:673 | ENTREZ:7157 | BRAF | TP53 | 1 | discovery | 285 | 577 | 39 | 37 | 938 | true | 938 |
ENTREZ:673 | ENTREZ:7157 | BRAF | TP53 | 1 | holdout | 74 | 144 | 15 | 7 | 240 | true | 240 |
ENTREZ:7015 | ENTREZ:472 | TERT | ATM | 8 | all | 912 | 20 | 235 | 11 | 1,178 | true | 1,178 |
ENTREZ:7015 | ENTREZ:472 | TERT | ATM | 8 | discovery | 727 | 17 | 185 | 9 | 938 | true | 938 |
ENTREZ:7015 | ENTREZ:472 | TERT | ATM | 8 | holdout | 185 | 3 | 50 | 2 | 240 | false | 240 |
ENTREZ:7015 | ENTREZ:4893 | TERT | NRAS | 1 | all | 888 | 44 | 232 | 14 | 1,178 | true | 1,178 |
ENTREZ:7015 | ENTREZ:4893 | TERT | NRAS | 1 | discovery | 705 | 39 | 185 | 9 | 938 | true | 938 |
ENTREZ:7015 | ENTREZ:4893 | TERT | NRAS | 1 | holdout | 183 | 5 | 47 | 5 | 240 | true | 240 |
ENTREZ:7015 | ENTREZ:53353 | TERT | LRP1B | 1 | all | 886 | 46 | 238 | 8 | 1,178 | true | 1,178 |
ENTREZ:7015 | ENTREZ:53353 | TERT | LRP1B | 1 | discovery | 705 | 39 | 186 | 8 | 938 | true | 938 |
ENTREZ:7015 | ENTREZ:53353 | TERT | LRP1B | 1 | holdout | 181 | 7 | 52 | 0 | 240 | false | 240 |
ENTREZ:7015 | ENTREZ:673 | TERT | BRAF | 1 | all | 882 | 50 | 198 | 48 | 1,178 | true | 1,178 |
ENTREZ:7015 | ENTREZ:673 | TERT | BRAF | 1 | discovery | 704 | 40 | 158 | 36 | 938 | true | 938 |
ENTREZ:7015 | ENTREZ:673 | TERT | BRAF | 1 | holdout | 178 | 10 | 40 | 12 | 240 | true | 240 |
ENTREZ:7015 | ENTREZ:7157 | TERT | TP53 | 3 | all | 318 | 614 | 95 | 151 | 1,178 | true | 1,178 |
ENTREZ:7015 | ENTREZ:7157 | TERT | TP53 | 3 | discovery | 250 | 494 | 74 | 120 | 938 | true | 938 |
ENTREZ:7015 | ENTREZ:7157 | TERT | TP53 | 3 | holdout | 68 | 120 | 21 | 31 | 240 | true | 240 |
ENTREZ:7157 | ENTREZ:127255 | TP53 | LRRIQ3 | 2 | all | 408 | 5 | 758 | 7 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:127255 | TP53 | LRRIQ3 | 2 | discovery | 320 | 4 | 608 | 6 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:127255 | TP53 | LRRIQ3 | 2 | holdout | 88 | 1 | 150 | 1 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:1496 | TP53 | CTNNA2 | 3 | all | 412 | 1 | 755 | 10 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:1496 | TP53 | CTNNA2 | 3 | discovery | 323 | 1 | 606 | 8 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:1496 | TP53 | CTNNA2 | 3 | holdout | 89 | 0 | 149 | 2 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:1499 | TP53 | CTNNB1 | 3 | all | 395 | 18 | 752 | 13 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:1499 | TP53 | CTNNB1 | 3 | discovery | 308 | 16 | 605 | 9 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:1499 | TP53 | CTNNB1 | 3 | holdout | 87 | 2 | 147 | 4 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:158358 | TP53 | KIAA2026 | 1 | all | 411 | 2 | 755 | 10 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:158358 | TP53 | KIAA2026 | 1 | discovery | 322 | 2 | 607 | 7 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:158358 | TP53 | KIAA2026 | 1 | holdout | 89 | 0 | 148 | 3 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:2045 | TP53 | EPHA7 | 6 | all | 410 | 3 | 753 | 12 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:2045 | TP53 | EPHA7 | 6 | discovery | 321 | 3 | 605 | 9 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:2045 | TP53 | EPHA7 | 6 | holdout | 89 | 0 | 148 | 3 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:26047 | TP53 | CNTNAP2 | 1 | all | 410 | 3 | 751 | 14 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:26047 | TP53 | CNTNAP2 | 1 | discovery | 322 | 2 | 603 | 11 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:26047 | TP53 | CNTNAP2 | 1 | holdout | 88 | 1 | 148 | 3 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:343450 | TP53 | KCNT2 | 2 | all | 409 | 4 | 758 | 7 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:343450 | TP53 | KCNT2 | 2 | discovery | 321 | 3 | 608 | 6 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:343450 | TP53 | KCNT2 | 2 | holdout | 88 | 1 | 150 | 1 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:345895 | TP53 | RSPH4A | 1 | all | 411 | 2 | 759 | 6 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:345895 | TP53 | RSPH4A | 1 | discovery | 322 | 2 | 608 | 6 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:345895 | TP53 | RSPH4A | 1 | holdout | 89 | 0 | 151 | 0 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:3717 | TP53 | JAK2 | 2 | all | 412 | 1 | 757 | 8 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:3717 | TP53 | JAK2 | 2 | discovery | 323 | 1 | 606 | 8 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:3717 | TP53 | JAK2 | 2 | holdout | 89 | 0 | 151 | 0 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:3739 | TP53 | KCNA4 | 1 | all | 408 | 5 | 757 | 8 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:3739 | TP53 | KCNA4 | 1 | discovery | 319 | 5 | 606 | 8 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:3739 | TP53 | KCNA4 | 1 | holdout | 89 | 0 | 151 | 0 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:3845 | TP53 | KRAS | 1 | all | 364 | 49 | 638 | 127 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:3845 | TP53 | KRAS | 1 | discovery | 284 | 40 | 512 | 102 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:3845 | TP53 | KRAS | 1 | holdout | 80 | 9 | 126 | 25 | 240 | true | 240 |
ENTREZ:7157 | ENTREZ:387 | TP53 | RHOA | 2 | all | 409 | 4 | 753 | 12 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:387 | TP53 | RHOA | 2 | discovery | 320 | 4 | 604 | 10 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:387 | TP53 | RHOA | 2 | holdout | 89 | 0 | 149 | 2 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:460 | TP53 | ASTN1 | 4 | all | 410 | 3 | 756 | 9 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:460 | TP53 | ASTN1 | 4 | discovery | 321 | 3 | 607 | 7 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:460 | TP53 | ASTN1 | 4 | holdout | 89 | 0 | 149 | 2 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:4683 | TP53 | NBN | 3 | all | 406 | 7 | 756 | 9 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:4683 | TP53 | NBN | 3 | discovery | 317 | 7 | 606 | 8 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:4683 | TP53 | NBN | 3 | holdout | 89 | 0 | 150 | 1 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:4893 | TP53 | NRAS | 1 | all | 386 | 27 | 734 | 31 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:4893 | TP53 | NRAS | 1 | discovery | 304 | 20 | 586 | 28 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:4893 | TP53 | NRAS | 1 | holdout | 82 | 7 | 148 | 3 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:5290 | TP53 | PIK3CA | 1 | all | 370 | 43 | 685 | 80 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:5290 | TP53 | PIK3CA | 1 | discovery | 290 | 34 | 550 | 64 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:5290 | TP53 | PIK3CA | 1 | holdout | 80 | 9 | 135 | 16 | 240 | true | 240 |
ENTREZ:7157 | ENTREZ:546 | TP53 | ATRX | 2 | all | 406 | 7 | 749 | 16 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:546 | TP53 | ATRX | 2 | discovery | 317 | 7 | 603 | 11 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:546 | TP53 | ATRX | 2 | holdout | 89 | 0 | 146 | 5 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:54790 | TP53 | TET2 | 2 | all | 411 | 2 | 754 | 11 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:54790 | TP53 | TET2 | 2 | discovery | 322 | 2 | 604 | 10 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:54790 | TP53 | TET2 | 2 | holdout | 89 | 0 | 150 | 1 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:55607 | TP53 | PPP1R9A | 2 | all | 411 | 2 | 757 | 8 | 1,178 | false | 1,178 |
ENTREZ:7157 | ENTREZ:55607 | TP53 | PPP1R9A | 2 | discovery | 322 | 2 | 607 | 7 | 938 | false | 938 |
ENTREZ:7157 | ENTREZ:55607 | TP53 | PPP1R9A | 2 | holdout | 89 | 0 | 150 | 1 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:5925 | TP53 | RB1 | 1 | all | 401 | 12 | 705 | 60 | 1,178 | true | 1,178 |
ENTREZ:7157 | ENTREZ:5925 | TP53 | RB1 | 1 | discovery | 316 | 8 | 570 | 44 | 938 | true | 938 |
ENTREZ:7157 | ENTREZ:5925 | TP53 | RB1 | 1 | holdout | 85 | 4 | 135 | 16 | 240 | false | 240 |
ENTREZ:7157 | ENTREZ:6416 | TP53 | MAP2K4 | 1 | all | 412 | 1 | 757 | 8 | 1,178 | false | 1,178 |
End of preview.
Final Directional Co-Mutation Dependency Atlas
Standalone fresh computation: every statistical result was recomputed from official raw DepMap 24Q4 Public v1, PRISM 19Q4 v4, Reactome and optional cited sources. No outputs, C1 shortlist, or checkpoints from historical projects were loaded.
The source code is under src/final_comutation/; experiment-section figures and tables are under results/Paper_Experiment_Section/. Computation status and limitations are under results/Audit/.
Findings for this particular run (dynamic)
- C1 conservative discoveries: 83
- Selected across-context results: 546
- Drug inference: {"causal_mechanism_established": false, "interpretation": "Conditional drug response support differs from A-by-B nonadditive interaction or clinical therapeutic effect", "n_AB_vs_Bonly_BH": 0, "n_AB_vs_Bonly_tested": 50, "n_PRISM_BH_concordant": 8, "n_PRISM_BY_concordant": 5, "n_PRISM_conditional_tested": 49, "n_annotated_drug_hypotheses": 62, "n_external_independently_validated": 0, "n_fresh_C1": 83, "n_strict_AxB_BH": 0, "n_strict_interactions_tested": 31, "raw_data_only_no_prior_results": true, "study": "FRESH raw-source drug-response followup"}
Data provenance and scope
Input providers: DepMap 24Q4 v1 (versioned figshare 27993248 v1), PRISM Repurposing 19Q4 v4 (figshare 9393293 v4), pinned Reactome 98, optionally Enrichr/MSigDB oncogenic signatures, cBioPortal selected TCGA cancer studies, and optional identified GDSC2. The raw input matrices and per-cell data are not redistributed here; the original providers should be cited and their terms reviewed.
Interpretation safeguards
- CRISPR and drug-response contrasts are observational; co-mutation states do not establish causal order or genetic synergy.
- A=mutated and B=additionally mutated versus A-only is the primary estimand. A×B and B-only contrasts are auxiliary.
- Multiplicity-adjusted associations are computational, not independent cohort or wet-lab validation.
No reported qualifying mutationis not verified wild type.- TCGA prevalence is not patient treatment response.
- Failed/underpowered and unavailable validation evidence is retained explicitly.
- Authors must inspect all exported evidence and methods before manuscript submission.
Reproducibility
Run the provided multi-cell Kaggle notebook or python -m final_comutation.pipeline. Source code and source manifests are preserved; see results/Paper_Experiment_Section/Methods_and_Evidence/Experiment_Section_Claim_Evidence_Methods.md.
- Downloads last month
- 281