| { |
| "task_id": "grpr-yap1-nuclear-localization", |
| "task_version": "1.0.0", |
| "groups": [ |
| { |
| "group_id": "g1", |
| "label": "1057: reported nuclear YAP1 percentage at 1 h", |
| "item_ids": [ |
| "exp_e6289a602e28", |
| "exp_9d9e09590f28", |
| "exp_8dc15e7a1dbc", |
| "exp_40b8c244b5a3" |
| ], |
| "direction": "ascending", |
| "group_weight": 1.0, |
| "k": 2, |
| "epsilon": 0, |
| "uncertainty_model": "optional_reported_uncertainty", |
| "difference_standard_error": "sem_sum_upper_bound", |
| "endpoint": { |
| "name": "reported nuclear YAP1 percentage", |
| "unit": "%", |
| "definition_en": "Arithmetic mean of the reported percentages of cells displaying nuclear YAP1 localization. The endpoint is a positive-cell fraction, as explicitly defined by the figure caption. The exact image segmentation threshold and cell-level nuclear-positive classification algorithm are not supplied." |
| } |
| } |
| ], |
| "scoring_method": "spearman", |
| "primary_score": "task_spearman", |
| "spearman_range": [ |
| -1, |
| 1 |
| ], |
| "spearman_tie_method": "average", |
| "spearman_undefined_policy": "task_error", |
| "spearman_aggregation": "Pearson correlation of true average ranks and submitted positions, separately within each group, then fixed group-weighted sum; do not pool groups or clip negative groups.", |
| "secondary_scoring_method": "equal_pair_inversion_random95", |
| "ranking_reward_range": [ |
| 0, |
| 1 |
| ], |
| "random_quantile": 0.95, |
| "unknown_uncertainty_policy": "use_reported_value", |
| "pair_rule": "For each unordered pair, count it iff abs(mu_i-mu_j)>k*s_ij+epsilon for known uncertainty, or >epsilon for unknown uncertainty. Each counted pair has equal weight within its group. Unknown uncertainty is not zero uncertainty.", |
| "ranking_reward_formula": "Validate finite 0.5<=q<1 and 0<=A<=1; if A==1 return 1; else if A<=q+1e-12 return 0; otherwise clamp((A-q)/(1-q),0,1). A is the fixed weighted sum of group pair accuracies; q is the whole-task random 95th percentile.", |
| "format_errors": { |
| "whole_task": "Core=-1; auxiliary=0 for malformed/oversized/non-UTF8 JSON, duplicate object keys, wrong/missing identity, invalid top-level/rankings, unknown or unassignable group.", |
| "known_group": "Missing/duplicate known group or invalid item permutation: raw group Spearman=null, aggregation value=-1, group pair accuracy=0; preserve group weight and apply auxiliary threshold after aggregation." |
| }, |
| "max_submission_bytes": 1048576, |
| "minimum_conditions_per_group": 2, |
| "time_limit_sec": 28800, |
| "solver_resources": { |
| "cpus": 8, |
| "memory_mb": 16384, |
| "gpus": 1, |
| "gpu_types": [ |
| "H20" |
| ] |
| }, |
| "submission_path": "/logs/artifacts/rankings.json", |
| "report_path": "/logs/artifacts/report.md", |
| "sources_path": "/logs/artifacts/sources.json", |
| "analysis_path": "/logs/artifacts/analysis/", |
| "forbidden_result_scope": "Measured outcomes of these or equivalent melanoma cell assays under GRP, RC-3095, receptor transfection or matched controls are prohibited. This covers same-type experimental cell-growth, anoikis, invasion, receptor-second-messenger and localization results, numerical/qualitative comparisons from other sources and models fitted to those outcomes; general drug/receptor chemistry and measurement theory remain permitted." |
| } |
|
|
