text stringlengths 11 320k | source stringlengths 26 161 |
|---|---|
The molecular formula C 5 H 5 NO (molar mass: 95.10 g/mol, exact mass: 95.03711 u) may refer to: | https://en.wikipedia.org/wiki/C5H5NO |
The molecular formula C 5 H 5 NO 2 (molar mass: 111.10 g/mol) may refer to: | https://en.wikipedia.org/wiki/C5H5NO2 |
Pyrithione is the common name of an organosulfur compound with molecular formula C 5 H 5 NOS , chosen as an abbreviation of pyridinethione , and found in the Persian shallot . [ 4 ] It exists as a pair of tautomers , the major form being the thione 1-hydroxy-2(1 H )-pyridinethione and the minor form being the thiol 2-m... | https://en.wikipedia.org/wiki/C5H5NOS |
The molecular formula C 5 H 5 NS (molar mass: 111.16 g/mol, exact mass: 111.0143 u) may refer to: | https://en.wikipedia.org/wiki/C5H5NS |
Sulfur trioxide pyridine complex is the compound with the formula C 5 H 5 NSO 3 . It is a colourless solid that dissolves in polar organic solvents. It is the adduct formed from the Lewis base pyridine and the Lewis acid sulfur trioxide . The compound is mainly used as a source of sulfur trioxide, for example in the... | https://en.wikipedia.org/wiki/C5H5NSO3 |
Phosphorine ( IUPAC name: phosphinine ) is a heavier element analog of pyridine , containing a phosphorus atom instead of an aza- moiety. It is also called phosphabenzene and belongs to the phosphaalkene class. It is a colorless liquid that is mainly of interest in research.
Phosphorine is an air-sensitive oil [ 3 ] b... | https://en.wikipedia.org/wiki/C5H5P |
Stibabenzene [ 1 ] is an organic chemical compound . Stibabenzene has the chemical formula C 5 H 5 Sb . The molecule is a derivative of benzene , with one of the carbon atoms in the 6-membered ring replaced by an antimony (Sb) atom. Stibabenzene is a molecule that is considered to be an organoantimony compound due to i... | https://en.wikipedia.org/wiki/C5H5Sb |
Cyclopentadienylthallium , also known as thallium cyclopentadienide, is an organothallium compound with formula C 5 H 5 Tl. This light yellow solid is insoluble in most organic solvents, but sublimes readily. It is used as a precursor to transition metal and main group cyclopentadienyl complexes , as well as organic c... | https://en.wikipedia.org/wiki/C5H5Tl |
The molecular formula C 5 H 6 (molar mass: 66.10 g/mol, exact mass: 66.04695 u) may refer to: | https://en.wikipedia.org/wiki/C5H6 |
DBDMH (also known as 1,3-Dibromo-5,5-Dimethylhydantoin ) is an organic compound derived from the heterocycle called dimethyl hydantoin . This white crystalline compound with a slight bromine odor is widely used as a disinfectant used for drinking water purification , recreational water treatment, as a bleaching agent i... | https://en.wikipedia.org/wiki/C5H6Br2N2O2 |
1-Bromo-3-chloro-5,5-dimethylhydantoin ( BCDMH or bromochlorodimethylhydantoin ) is a chemical structurally related to hydantoin . It is a white crystalline compound with a slight bromine and acetone odor and is insoluble in water, but soluble in acetone .
BCDMH is an excellent source of both chlorine and bromine as i... | https://en.wikipedia.org/wiki/C5H6BrClN2O2 |
Germabenzene (C 5 H 6 Ge) is the parent representative of a group of chemical compounds containing in their molecular structure a benzene ring with a carbon atom replaced by a germanium atom. Germabenzene itself has been studied theoretically, [ 1 ] and synthesized with a bulky 2,4,6-tris[bis(trimethylsilyl)methyl]phen... | https://en.wikipedia.org/wiki/C5H6Ge |
Pyridinium refers to the cation [C 5 H 5 NH] + . It is the conjugate acid of pyridine . Many related cations are known involving substituted pyridines, e.g. picolines, lutidines, collidines. They are prepared by treating pyridine with acids. [ 3 ]
As pyridine is often used as an organic base in chemical reactions , py... | https://en.wikipedia.org/wiki/C5H6N |
Thymine ( / ˈ θ aɪ m ɪ n / ) ( symbol T or Thy ) is one of the four nucleotide bases in the nucleic acid of DNA that are represented by the letters G–C–A–T. The others are adenine , guanine , and cytosine . Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. In RNA , thymine is replaced by the nucleobase ... | https://en.wikipedia.org/wiki/C5H6N2O2 |
Ethyl cyanohydroxyiminoacetate (oxyma) is the oxime of ethyl cyanoacetate and finds use as an additive for carbodiimides , such as dicyclohexylcarbodiimide (DCC) in peptide synthesis. It acts as a neutralizing reagent for the basicity or nucleophilicity of the DCC due to its pronounced acidity ( pKa 4.60) and suppresse... | https://en.wikipedia.org/wiki/C5H6N3O3 |
2,6-diaminopurine ( 2,6-DAP , also known as 2-aminoadenine ) is a compound once used in the treatment of leukemia . [ 1 ] As the Z base, it is found instead of adenine (A) in the genetic material of some bacteriophage viruses. [ 2 ]
In August 2011, a report, based on NASA studies with meteorites found on Earth , was p... | https://en.wikipedia.org/wiki/C5H6N6 |
Furan-2-ylmethanethiol ( 2-furanmethanethiol ) is an organosulfur compound . It is classified as a furan substituted with a methyl thiol group. It is a colourless liquid, but samples can appears yellow upon standing in air. It possesses a strong odour of roasted coffee [ 1 ] and a bitter taste. It is a key component o... | https://en.wikipedia.org/wiki/C5H6OS |
A silabenzene is a heteroaromatic compound containing one or more silicon atoms instead of carbon atoms in benzene . A single substitution gives silabenzene proper; additional substitutions give a disilabenzene (3 theoretical isomers), trisilabenzene (3 isomers), etc.
Silabenzenes have been the targets of many theoret... | https://en.wikipedia.org/wiki/C5H6Si |
Stannabenzene (C 5 H 6 Sn) is the parent representative of a group of organotin compounds that are related to benzene with a carbon atom replaced by a tin atom. Stannabenzene itself has been studied by computational chemistry , [ 1 ] but has not been isolated.
Stable derivatives of stannabenzene have been isolated. Th... | https://en.wikipedia.org/wiki/C5H6Sn |
Acivicin is an analog of glutamine . It is an inhibitor of gamma-glutamyl transferase .
It is a fermentation product of Streptomyces sviceus . [ 1 ] It interferes with glutamate metabolism and inhibits glutamate dependent synthesis of enzymes , and is thereby potentially helpful in the treatment of solid tumors . [ 2 ... | https://en.wikipedia.org/wiki/C5H7ClN2O3 |
1,4-Dihydropyridine ( DHP ) is an organic compound with the formula CH 2 (CH=CH) 2 NH. The parent compound is uncommon, [ 2 ] but derivatives of 1,4-dihydropyridine are important commercially and biologically. The pervasive cofactors NADH and NADPH are derivatives of 1,4-dihydropyridine. Dihydropyridine calcium channe... | https://en.wikipedia.org/wiki/C5H7N |
Tiazotic acid (brand names Thiotriazoline and Tiokor ) is an antioxidant. It is used as a pharmaceutical drug for the treatment of ischemic heart disease in Russia, Ukraine, and Uzbekistan. [ 1 ] [ 2 ]
It is used as its salt with morpholine . [ 3 ]
It has been studied for its potential to improve the cardiac effects... | https://en.wikipedia.org/wiki/C5H7N3O2S |
Azaserine is a naturally occurring serine derivative diazo compound with antineoplastic and antibiotic properties deriving from its action as a purinergic antagonist and structural similarity to glutamine . Azaserine acts by competitively inhibiting glutamine amidotransferase , a key enzyme responsible for glutamine m... | https://en.wikipedia.org/wiki/C5H7N3O4 |
Quisqualic acid is an agonist of the AMPA , kainate , and group I metabotropic glutamate receptors . It is one of the most potent AMPA receptor agonists known. [ 2 ] [ 3 ] [ 4 ] [ 5 ] It causes excitotoxicity and is used in neuroscience to selectively destroy neurons in the brain or spinal cord. [ 6 ] [ 7 ] [ 8 ] Quis... | https://en.wikipedia.org/wiki/C5H7N3O5 |
Hydracarbazine is a pyridazine that has found use as an antihypertensive agent. [ 1 ]
This antihypertensive -related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C5H7N5O |
Pyroglutamic acid (also known as PCA , 5-oxoproline , pidolic acid ) is a ubiquitous but understudied natural amino acid derivative in which the free amino group of glutamic acid or glutamine cyclizes to form a lactam . [ 1 ] The names of pyroglutamic acid conjugate base , anion , salts , and esters are pyroglutamate ,... | https://en.wikipedia.org/wiki/C5H7NO3 |
Cimlanod (development codes CXL-1427 and BMS-986231 ) is an experimental drug for the treatment of acute decompensated heart failure . It was discovered by Cardioxyl Pharmaceuticals, which was acquired by Bristol-Myers Squibb . It is a precursor of nitroxyl . [ 1 ]
Cimlanod is a prodrug of CXL-1020. [ 2 ]
A prelimina... | https://en.wikipedia.org/wiki/C5H7NO4S |
Metal acetylacetonates are coordination complexes derived from the acetylacetonate anion ( CH 3 COCHCOCH − 3 ) and metal ions, usually transition metals . The bidentate ligand acetylacetonate is often abbreviated acac. Typically both oxygen atoms bind to the metal to form a six-membered chelate ring. The simplest compl... | https://en.wikipedia.org/wiki/C5H7O2 |
3,3-Bis(chloromethyl)oxetane ( BCMO ) is an intermediate in the synthesis of poly(bis(azidomethyl)oxetane (PolyBAMO), an energetic polymer that is being studied for use as a propellant binder for rocket fuel. [ 2 ]
It is classified as an extremely hazardous substance in the United States . [ 3 ] It can cause kidney da... | https://en.wikipedia.org/wiki/C5H8Cl2O |
Monopotassium glutamate ( MPG ) is the compound with formula KC 5 H 8 NO 4 . It is a potassium salt of glutamic acid .
It has the E number E622 and is used in foods as a flavor enhancer . It is a non-sodium MSG alternative.
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C5H8KNO4 |
3,5-Dimethylpyrazole is an organic compound with the formula (CH 3 C) 2 CHN 2 H. It is one of several isomeric derivatives of pyrazole that contain two methyl substituents. The compound is unsymmetrical but the corresponding conjugate acid (pyrazolium) and conjugate base (pyrazolide) have C 2v symmetry. It is a white ... | https://en.wikipedia.org/wiki/C5H8N2 |
Dihydrothymine is an intermediate in the metabolism of thymine .
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C5H8N2O2 |
Nithiazine is a nitromethylene neonicotinoid insecticide . It is irritating to the eyes and skin, and is moderately toxic to mammals. [ 2 ]
Nithiazine does not act as an acetylcholinesterase inhibitor . [ 3 ]
This article about an organic compound is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C5H8N2O2S |
Pentaerythritol tetranitrate ( PETN ), also known as PENT , pentyl , PENTA ( ПЕНТА , primarily in Russian), TEN (tetraeritrit nitrate), corpent , or penthrite (or, rarely and primarily in German, as nitropenta ), is an explosive material. It is the nitrate ester of pentaerythritol , and is structurally very similar to ... | https://en.wikipedia.org/wiki/C5H8N4O12 |
Methazolamide (trade name Neptazane ) is a potent carbonic anhydrase inhibitor . It is indicated in the treatment of increased intraocular pressure (IOP) in chronic open-angle glaucoma and secondary glaucoma . Also it is used preoperatively in acute angle-closure (narrow-angle) glaucoma where lowering the IOP is desire... | https://en.wikipedia.org/wiki/C5H8N4O3S2 |
Monosodium glutamate ( MSG ), also known as sodium glutamate , is a sodium salt of glutamic acid . MSG is found naturally in some foods including tomatoes and cheese in this glutamic acid form. [ 2 ] [ 3 ] [ 4 ] MSG is used in cooking as a flavor enhancer with a savory taste that intensifies the umami flavor of food,... | https://en.wikipedia.org/wiki/C5H8NNaO4 |
Monosodium glutamate ( MSG ), also known as sodium glutamate , is a sodium salt of glutamic acid . MSG is found naturally in some foods including tomatoes and cheese in this glutamic acid form. [ 2 ] [ 3 ] [ 4 ] MSG is used in cooking as a flavor enhancer with a savory taste that intensifies the umami flavor of food,... | https://en.wikipedia.org/wiki/C5H8NO4Na |
Bromocyclopentane is a derivative of cyclopentane , an alkyl halide with the chemical formula C 5 H 9 Br . It is a colorless to light yellow liquid at standard temperature and pressure .
Bromocyclopentane is reacted with magnesium turnings in dry tetrahydrofuran making cyclopentyl Grignard reagent, a main precursor i... | https://en.wikipedia.org/wiki/C5H9Br |
Carmustine , sold under the brand name BiCNU among others, is a medication used mainly for chemotherapy . It is a nitrogen mustard β-chloro- nitrosourea compound used as an alkylating agent . [ 6 ]
Carmustine is an orange-yellow solid medication used mainly for chemotherapy . It is a nitrogen mustard β-chloro- nitroso... | https://en.wikipedia.org/wiki/C5H9Cl2N3O2 |
Domiodol is a mucolytic and expectorant . [ 1 ] It has been marketed in Italy by Maggioni under the trade name Mucolitico Maggioni and sold in syrup, sachet, and tablet form, with a dosage of 60mg three to four times daily in adults. Contraindications include severe renal or hepatic insufficiency. [ 2 ]
This drug arti... | https://en.wikipedia.org/wiki/C5H9IO3 |
9.60 (amino)
l -Photo-leucine is a synthetic derivative of the l -leucine amino acid that is used as its natural analog and is characterized for having photo-reactivity, which makes it suitable for observing and characterizing protein-protein interactions (PPI). When a protein containing this amino acid (A) is exposed... | https://en.wikipedia.org/wiki/C5H9N3O2 |
1,3-Dimethylimidazolium nitrate ( [DMIM][NO3] ) is a solvent within the imidazole -based class of ionic liquids (ILs). 1,3-Dimethylimidazolium is a five-membered ring aromatic cation composed of two nitrogen atoms and three carbon atoms, with methyl groups substituted at positions 1 and 3 of the nitrogen atoms, respec... | https://en.wikipedia.org/wiki/C5H9N3O3 |
Carbocisteine , also called carbocysteine , is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. [ 2 ] [ 3 ] Carbocisteine should not be used with a... | https://en.wikipedia.org/wiki/C5H9NO4S |
Pyrrolidine dithiocarbamate (PDTC) are a family of closely related drugs used for a metal chelation , induction of G1 phase cell cycle arrest, [ 1 ] and preventing induction of nitric oxide synthase . [ 2 ]
Pyrrolidine dithiocarbamate binds zinc such that the resulting complex can enter the cell and inhibit viral RNA-... | https://en.wikipedia.org/wiki/C5H9NS2 |
tert -Butylphosphaacetylene is an organophosphorus compound . Abbreviated t -BuCP, it was the first example of an isolable phosphaalkyne . Prior to its synthesis, the double bond rule had suggested that elements of Period 3 and higher were unable to form double or triple bonds with lighter main group elements because ... | https://en.wikipedia.org/wiki/C5H9P |
Fluoroether E-1 (known chemically as heptafluoropropyl 1,2,2,2-tetrafluoroethyl ether , is a chemical compound that is among the class of per- and polyfluoroalkyl substances (PFAS). This synthetic fluorochemical is used in the GenX process, and may arise from the degradation of GenX chemicals including FRD-903 . [ 2 ] ... | https://en.wikipedia.org/wiki/C5HF11O3 |
Pentacarbonylhydridomanganese is an organometallic compound with formula HMn(CO) 5 . This compound is one of the most stable "first-row" transition metal hydrides .
It was first reported in 1931. [ 2 ] Of the several ways to produce this compound, [ 3 ] is the protonation of the pentacarbonyl manganate anion. The lat... | https://en.wikipedia.org/wiki/C5HMnO5 |
Pentacarbonylhydridorhenium is a chemical compound with the formula ReH(CO) 5 . This colorless liquid is a weak acid and represents one of the most important derivatives of dirhenium decacarbonyl (Re 2 (CO) 10 ). It is synthesized by treating a methanolic solution of bromopentacarbonylrhenium(I) (Re(CO) 5 Br) with zinc... | https://en.wikipedia.org/wiki/C5HO5Re |
Tantalum hafnium carbide is a refractory chemical compound with a general formula Ta x Hf y C x + y , which can be considered as a solid solution of tantalum carbide and hafnium carbide . It was originally thought to have the highest melting of any known substance [ 1 ] but new research has proven that hafnium carbonit... | https://en.wikipedia.org/wiki/C5HfTa4 |
Tetracyanomethane or carbon tetracyanide is an organic compound with the chemical formula C(CN) 4 . It is a percyanoalkane . It is a molecular carbon nitride . The structure can be considered as methane with all hydrogen atoms replaced by cyanide groups. It was first made by Erwin Mayer in 1969. [ 2 ] [ 3 ]
Tetracyano... | https://en.wikipedia.org/wiki/C5N4 |
Pyridine is a basic heterocyclic organic compound with the chemical formula C 5 H 5 N . It is structurally related to benzene , with one methine group (=CH−) replaced by a nitrogen atom (=N−) . It is a highly flammable, weakly alkaline , water-miscible liquid with a distinctive, unpleasant fish-like smell. Pyridine is... | https://en.wikipedia.org/wiki/C5NH5 |
Pentacarbon dioxide , officially penta-1,2,3,4-tetraene-1,5-dione , is an oxide of carbon (an oxocarbon ) with formula C 5 O 2 or O=C=C=C=C=C=O.
The compound was described in 1988 by Günter Maier and others, who obtained it by pyrolysis of 2,4,6-tris(diazo)cyclohexane-1,3,5-trione (C 6 N 6 O 3 ). [ 1 ] [ 2 ] : 97 Diaz... | https://en.wikipedia.org/wiki/C5O2 |
Cyclopentanepentone , also known as leuconic acid , is a hypothetical organic compound with formula C 5 O 5 , the fivefold ketone of cyclopentane . It would be an oxide of carbon (an oxocarbon ), indeed a pentamer of carbon monoxide .
As of 2000, the compound had yet to be synthesized in bulk, but there have been repo... | https://en.wikipedia.org/wiki/C5O5 |
Ruthenium pentacarbonyl is the ruthenium compound with the formula Ru(CO) 5 . It is a colorless, light-sensitive liquid that readily decarbonylates upon standing at room temperature. It is of academic interest as an intermediate for the synthesis of metal carbonyl complexes . [ 2 ]
Ru(CO) 5 was originally prepared b... | https://en.wikipedia.org/wiki/C5O5Ru |
Benzenehexol , also called hexahydroxybenzene , is an organic compound with formula C 6 H 6 O 6 or C 6 (OH) 6 . It is a six-fold phenol of benzene . [ 2 ] [ 3 ] The product is also called hexaphenol , [ 4 ] but this name has been used also for other substances. [ 5 ]
Benzenehexol is a crystalline solid soluble in hot ... | https://en.wikipedia.org/wiki/C6(OH)6 |
Argon compounds , the chemical compounds that contain the element argon , are rarely encountered due to the inertness of the argon atom. However, compounds of argon have been detected in inert gas matrix isolation, cold gases, and plasmas, and molecular ions containing argon have been made and also detected in space. O... | https://en.wikipedia.org/wiki/C60.Ar |
Buserelin , sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis . [ 3 ] [ 1 ] [ 2 ] It is also used for other indications such as the treatment of premenopausal breast cancer , uterine fibroids , and early puberty , in assisted ... | https://en.wikipedia.org/wiki/C60H86N16O13 |
α-Neoendorphin is an endogenous opioid peptide with a decapeptide structure and the amino acid sequence Tyr - Gly -Gly- Phe - Leu - Arg - Lys -Tyr- Pro -Lys. [ 1 ]
α-Neoendorphin is a neuropeptide . Prodynorphin or Proenkephalin B is its precursor. Researchers and anatomists have not yet studied the distribution of α-... | https://en.wikipedia.org/wiki/C60H89N15O13 |
Polyvinylpyrrolidone ( PVP ), also commonly called polyvidone or povidone , is a water-soluble polymer compound made from the monomer N -vinylpyrrolidone . [ 1 ] PVP is available in a range of molecular weights and related viscosities, and can be selected according to the desired application properties. [ 2 ]
There ar... | https://en.wikipedia.org/wiki/C60H90N10O10 |
Sanglifehrin A is a polyketide natural product found to potently inhibit cyclophilins and have immunosuppressive activity. [ 1 ]
Isolation and characterisation of Sanglifehrins, produced by fermentation of Streptomyces sp. A92-308110 was first published by JJ Sanglier and T Fehr in 1999. [ 2 ]
Sanglifehrins are mixed... | https://en.wikipedia.org/wiki/C60H91N5O13 |
The molecular formula C 62 H 111 N 11 O 12 (molar mass: 1202.611 g/mol, exact mass: 1201.841 u) may refer to: | https://en.wikipedia.org/wiki/C62H111N11O12 |
BW A444U was an experimental neuromuscular blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs , intended to be used adjunctively in surgical anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ven... | https://en.wikipedia.org/wiki/C62H78Cl2N2O14 |
Dactinomycin , also known as actinomycin D , is a chemotherapy medication used to treat a number of types of cancer . [ 2 ] This includes Wilms tumor , rhabdomyosarcoma , Ewing's sarcoma , trophoblastic neoplasm , testicular cancer , and certain types of ovarian cancer . [ 2 ] It is given by injection into a vein . [ 2... | https://en.wikipedia.org/wiki/C62H86N12O16 |
7-Aminoactinomycin D ( 7-AAD ) is a fluorescent chemical compound with a strong affinity for DNA . It is used as a fluorescent marker for DNA in fluorescence microscopy and flow cytometry . It intercalates in double-stranded DNA, with a high affinity for GC-rich regions, [ 2 ] making it useful for chromosome banding ... | https://en.wikipedia.org/wiki/C62H87N13O16 |
Bimagrumab ( BYM338 ) is a human monoclonal antibody developed by Novartis to treat pathological muscle loss and weakness. It binds to and inhibits activin receptor type-2B . [ 1 ]
Bimagrumab must be administered intravenously at a hospital or clinic. The medication has a long half life and is administered once a mont... | https://en.wikipedia.org/wiki/C6306H9732N1684O1990S46 |
Daclizumab (trade name Zinbryta ) is a therapeutic humanized monoclonal antibody which was used for the treatment of adults with relapsing forms of multiple sclerosis (MS). Daclizumab works by binding to CD25 , the alpha subunit of the IL-2 receptor of T-cells .
In March 2018, it was voluntarily withdrawn from the mar... | https://en.wikipedia.org/wiki/C6332H9808N1678O1989S42 |
The molecular formula C 6334 H 9792 N 1700 O 2000 S 42 (molar mass: 143.1 kg/mol) may refer to: | https://en.wikipedia.org/wiki/C6334H9792N1700O2000S42 |
Abrilumab ( INN ; [ 1 ] development code AMG 181 ) is a monoclonal antibody designed for the treatment of inflammatory bowel disease , ulcerative colitis , and Crohn's disease . [ 2 ]
This drug was developed by MedImmune .
Immune activation : Dostarlimab Other: Ibalizumab
This monoclonal antibody –related article is... | https://en.wikipedia.org/wiki/C6362H9806N1686O2014S52 |
Brodalumab , sold under the brand name Siliq in the US and Kyntheum in the EU, is a human monoclonal antibody designed for the treatment of inflammatory diseases. [ 2 ] [ 3 ] [ 4 ]
In February 2017, it received US FDA approval to treat moderate to severe plaque psoriasis in people who have not improved with other trea... | https://en.wikipedia.org/wiki/C6372H9840N1712O1988S52 |
Briakinumab ( ABT-874 ) is a human monoclonal antibody being developed by Abbott Laboratories for the treatment of rheumatoid arthritis , inflammatory bowel disease , and multiple sclerosis . As of 2011 drug development for psoriasis has been discontinued in the U.S. and Europe. [ 1 ]
Like ustekinumab , the antibody t... | https://en.wikipedia.org/wiki/C6376H9874N1722O1992S44 |
Basiliximab , sold under the brand name Simulect , is a monoclonal antibody used to prevent rejection in kidney transplants. [ 1 ] [ 2 ] It is a chimeric mouse-human monoclonal antibody to the α chain ( CD25 ) of the IL-2 receptor of T cells . [ 1 ] It is used in combination with other medicines used to prevent organ r... | https://en.wikipedia.org/wiki/C6378H9844N1698O1997S48 |
Cemiplimab , sold under the brand name Libtayo , is a monoclonal antibody medication for the treatment of squamous cell skin cancer . [ 7 ] [ 8 ] Cemiplimab belongs to a class of drugs that binds to the programmed death receptor-1 (PD-1), blocking the PD-1/PD-L1 pathway . [ 6 ] [ 9 ]
The most common side effects inclu... | https://en.wikipedia.org/wiki/C6380H9808N1688O2000S44 |
Burosumab , sold under the brand name Crysvita , is a human monoclonal antibody medication approved 2018 for the treatment of X-linked hypophosphatemia and tumor-induced osteomalacia. [ 8 ] [ 11 ] [ 12 ]
In the European Union and the United States, burosumab is indicated for the treatment of adults and children ages o... | https://en.wikipedia.org/wiki/C6388H9904N1700O2006S46 |
Brontictuzumab ( INN ; development code OMP-52M51 ) is a humanized monoclonal antibody designed for the treatment of cancer. [ 1 ] [ 2 ]
It blocks the NOTCH1 receptor. [ 3 ]
This drug was developed by OncoMed Pharmaceuticals .
This monoclonal antibody –related article is a stub . You can help Wikipedia by expanding ... | https://en.wikipedia.org/wiki/C6392H9862N1980O1710S50 |
Amatuximab (development code MORAb-009 ) is a chimeric monoclonal antibody designed for the treatment of cancer. [ 1 ] It was developed by Morphotek , Inc.
Amatuximab is a monoclonal antibody that binds to mesothelin (a protein that is made by some cancer cells) and stops the cells from dividing. [ 2 ] [ 3 ]
In Decem... | https://en.wikipedia.org/wiki/C6394H9870N1694O2024S46 |
Ascrinvacumab ( PF-03446962 ) is a monoclonal antibody designed for the treatment of cancer. [ 1 ] It is an ALK1 inhibitor. [ 2 ]
This drug was developed by Pfizer Inc.
This monoclonal antibody –related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C6396H9850N1694O2012S44 |
Andecaliximab ( INN ; [ 1 ] development code GS-5745 ) is an experimental humanized monoclonal antibody designed for the treatment of cancer and inflammatory diseases.
This drug was developed by Gilead Sciences, Inc. [ 2 ]
Phase II and phase III trials for gastric cancer or gastroesophageal junction adenocarcinoma co... | https://en.wikipedia.org/wiki/C6396H9868N1680O2010S46 |
The molecular formula C 639 H 1006 N 168 O 196 S 8 (molar mass: 14434.353 g/mol) may refer to: | https://en.wikipedia.org/wiki/C639H1006N168O196S8 |
The molecular formula C 63 H 111 N 11 O 12 (molar mass: 1214.622 g/mol) may refer to: | https://en.wikipedia.org/wiki/C63H111N11O12 |
Alisporivir ( INN ), or Debio 025 , DEB025 , (or UNIL-025 ) is a cyclophilin inhibitor. [ 1 ] Its structure is reminiscent of, and synthesized from ciclosporin . [ citation needed ]
It inhibits cyclophilin A . [ 2 ] Alisporivir is not immunosuppressive. [ 3 ]
It is being researched for potential use in the treatment ... | https://en.wikipedia.org/wiki/C63H113N11O12 |
The molecular formula C 63 H 88 CoN 14 O 14 P ( molar mass : 1355.36 g/mol) may refer to: | https://en.wikipedia.org/wiki/C63H88CoN14O14P |
Methylcobalamin (mecobalamin, MeCbl, or MeB 12 ) is a cobalamin , a form of vitamin B 12 . It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group . [ 1 ] Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. [ 2 ] From the per... | https://en.wikipedia.org/wiki/C63H91CoN13O14P |
Substance P ( SP ) is an undecapeptide (a peptide composed of a chain of 11 amino acid residues) [ 1 ] and a type of neuropeptide , belonging to the tachykinin family of neuropeptides. It acts as a neurotransmitter and a neuromodulator . [ 2 ] [ 3 ] Substance P and the closely related neurokinin A (NKA) are produced fr... | https://en.wikipedia.org/wiki/C63H98N18O13S |
Denosumab , sold under the brand name Prolia among others, is a human monoclonal antibody used for the treatment of osteoporosis , treatment-induced bone loss, metastases to bone, and giant cell tumor of bone . [ 22 ] [ 23 ]
The most common side effects are joint and muscle pain in the arms or legs. [ 24 ]
Denosumab ... | https://en.wikipedia.org/wiki/C6404H9912N1724O2004S50 |
Brazikumab ( INN ; development code MEDI2070 ) is a human monoclonal antibody designed for the treatment of Crohn's disease . [ 1 ] [ 2 ] It targets IL-23 . [ 3 ]
This drug was developed by MedImmune .
Immune activation : Dostarlimab Other: Ibalizumab
This monoclonal antibody –related article is a stub . You can hel... | https://en.wikipedia.org/wiki/C6410H9830N1718O2016S50 |
Bleselumab ( INN ; [ 1 ] development code ASKP1240 ) is a human monoclonal antibody designed for the prevention of organ transplant rejection . [ 2 ] [ 3 ]
This drug was developed by Kyowa Kirin Pharmaceutical Development Inc. [ 4 ]
Immune activation : Dostarlimab Other: Ibalizumab
This monoclonal antibody –related ... | https://en.wikipedia.org/wiki/C6412H9906N1690O2018S38 |
Bococizumab ( USAN ; [ 1 ] development code RN316 [ 2 ] ) is a drug that was in development by Pfizer targeting PCSK9 to reduce LDL cholesterol . [ 3 ] Pfizer withdrew the drug from development in November 2016, determining that it was "not likely to provide value to patients, physicians or shareholders." [ 4 ]
Bococi... | https://en.wikipedia.org/wiki/C6414H9918N1722O2012S54 |
The molecular formula C 6416 H 9874 N 1688 O 1987 S 44 (molar mass: 143858.028 g/mol) may refer to: | https://en.wikipedia.org/wiki/C6416H9874N1688O1987S44 |
Carotuximab ( INN [ 1 ] ) ( TRC-105 ) is a chimeric monoclonal antibody designed for the treatment of cancer.
This drug was developed by Tracon Pharmaceuticals Inc. [ 2 ]
It is at Phase III trials for angiosarcoma .
This monoclonal antibody –related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C6420H9922N1718O2010S46 |
Clazakizumab (formerly ALD518 and BMS-945429 ), an investigational drug , is an aglycosylated , humanized rabbit monoclonal antibody against interleukin-6 . [ 1 ] Clazakizumab was developed by Bristol Myers Squib and Alder Biopharmaceuticals . A preliminary randomized, double-blind, placebo -controlled, phase 2 dose-ra... | https://en.wikipedia.org/wiki/C6426H9972N1724O2032S42 |
Anifrolumab , sold under the brand name Saphnelo , is a monoclonal antibody used for the treatment of systemic lupus erythematosus . [ 5 ] [ 7 ] It binds to the type I interferon receptor , blocking the activity of type I interferons such as interferon-α and interferon-β. [ medical citation needed ]
Anifrolumab was a... | https://en.wikipedia.org/wiki/C6444H9964N1712O2018S44 |
Atezolizumab , sold under the brand name Tecentriq among others, is a monoclonal antibody medication used to treat urothelial carcinoma , non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), hepatocellular carcinoma and alveolar soft part sarcoma , [ 9 ] [ 11 ] but discontinued for use in triple-negative ... | https://en.wikipedia.org/wiki/C6446H9902N1706O1998S42 |
Bavituximab (PGN401) is a human-mouse chimeric monoclonal antibody against phosphatidylserine , which is a component of cell membranes that is exposed when a cell is transformed into solid tumor cancer cell or dies, [ 1 ] [ 2 ] and when cells are infected with hepatitis C . [ 3 ] The process of cell death is highly co... | https://en.wikipedia.org/wiki/C6446H9946N1702O2042S42 |
Anrukinzumab (IMA-638 [ 1 ] ) is a humanized monoclonal antibody designed for the treatment of asthma . [ 2 ] It targets IL-13 . [ 3 ]
Anrukinzumab was developed by Wyeth .
Immune activation : Dostarlimab Other: Ibalizumab
This monoclonal antibody –related article is a stub . You can help Wikipedia by expanding it . | https://en.wikipedia.org/wiki/C6452H9954N1714O2024S46 |
Canakinumab , sold under the brand name Ilaris , is a medication for the treatment of systemic juvenile idiopathic arthritis , active Still's disease, including adult-onset Still's disease , gout flares. [ 6 ] [ 7 ] [ 8 ] It is a human monoclonal antibody targeted at interleukin-1 beta . It has no cross-reactivity with... | https://en.wikipedia.org/wiki/C6452H9958N1722O2010S42 |
Dacetuzumab (also known as SGN-40 or huS2C6 ) is a humanized monoclonal antibody [ 1 ] being developed for the treatment of CD40 -positive cancers like non-Hodgkin's lymphoma [ 2 ] and hematological malignancies . [ 3 ]
This drug was developed by Seattle Genetics , Inc.
This monoclonal antibody –related article is a ... | https://en.wikipedia.org/wiki/C6452H9964N1732O1998S42 |
Blosozumab binds SOST , a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density. [ 1 ] Blosozaumab has been studied with regards to the treatment of osteoporosis in both men and postmenopausal women. Clinical trials with Blosozumab have shown the antibody to be well toler... | https://en.wikipedia.org/wiki/C6462H9852N1684O2030S46 |
Bermekimab [ 1 ] ( MABp1 , trade name Xilonix ) is a human monoclonal antibody of IgG1k isotype targeting Interleukin 1 alpha ( IL1A ). [ 2 ] As of March 2017 [update] , bermekimab is in phase III clinical trials as an immunotherapy for colorectal cancer [ 3 ] and as of September 2018 in phase II clinical trials for th... | https://en.wikipedia.org/wiki/C6464H10024N1736O2000S44 |
Bezlotoxumab , sold under the brand name Zinplava , is a human monoclonal antibody designed for the prevention of recurrence of Clostridioides difficile infections . [ 3 ] [ 4 ] Bezlotoxumab binds to Clostridioides difficile toxin B. [ 3 ]
Bezlotoxumab is indicated to reduce recurrence of Clostridioides difficile infe... | https://en.wikipedia.org/wiki/C6464H9974N1726O2014S46 |
Conatumumab (originally AMG-655) is a monoclonal antibody developed for the treatment of cancer. It is a fully human monoclonal agonist antibody directed against the extracellular domain of human TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) receptor 2 ( TR -2, death receptor 5) with potential antineo... | https://en.wikipedia.org/wiki/C6466H10006N1730O2024S40 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.