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==General==
*Usually ''cerebellar''.
**occassionally brainstem or spinal cord. Supratentorial tumors are exceptionally rare.
*Typically in adults.<ref>{{Cite journal | last1 = Kassardjian | first1 = CD. | last2 = Macdonald | first2 = RL. | last3 = Munoz | first3 = DG. | title = Hemangioblastomas in the elderly: epidemiology and clinical characteristics. | journal = J Clin Neurosci | volume = 21 | issue = 7 | pages = 1205-8 | month = Jul | y...
*Associated with [[von Hippel-Lindau syndrome]].
*Symptomatic when CSF flow is impaired.
*WHO grade I (ICD-O: 9161/1).<ref>URL: [http://www.expertconsultbook.com/expertconsult/ob/book.do?method=display&type=bookPage&decorator=none&eid=4-u1.0-B978-1-4160-4580-9..00019-8--sc0155&isbn=978-1-4160-4580-9 http://www.expertconsultbook.com/expertconsult/ob/book.do?method=display&type=bookPage&decorator=none&eid=4-...
==Macroscopy==
*Red to yellow nodules, highly vascularized.
*75% are cystic tumors.
**Peripheral solid portion.
==Microscopic==
Features:<ref>URL: [http://emedicine.medscape.com/article/340994-media http://emedicine.medscape.com/article/340994-media]. Accessed on: 23 June 2010.</ref>
*Vascular.
*Polygonal stromal cells with:
**Hyperchromatic nuclei.
**Vacuolar cytoplasm.
*Occassionally extensive sclerosis.
Note:
*Based on the stromal content, some classify the tumors as "cellular" and "reticular".<ref>{{Cite journal | last1 = Hasselblatt | first1 = M. | last2 = Jeibmann | first2 = A. | last3 = Gerss | first3 = J. | last4 = Behrens | first4 = C. | last5 = Rama | first5 = B. | last6 = Wassmann | first6 = H. | last7 = Paulus | f...
DDx:
*Metastatic [[clear cell renal cell carcinoma]].
===Images===
<gallery>
Image:Cerebellar_hemangioblastoma_intermed_mag.jpg | Hemangioblastoma - intermed. mag. (WC)
Image:Cerebellar_hemangioblastoma_high_mag.jpg | Hemangioblastoma - high mag. (WC)
Image:Hemangioblastoma_-_nse_-_intermed_mag.jpg | Hemangioblastoma - NSE - intermed. mag. (WC)
File:Hemangioblastoma - nse - high mag.jpg | Hemangioblastoma - NSE - high mag. (WC)
File:Hemangioblastoma Histology CD31.jpg | Hemangioblastoma - CD31. (WC/marvin101)
File:Hippel Lindau.gif | Hemangioblastomas in Hippel-Lindau disease (PlosONE).
</gallery>
www:
*[http://path.upmc.edu/cases/case342.html Hemangioblastoma - several images (upmc.edu)].
==IHC==
Features:<ref>URL: [http://www.nature.com/modpathol/journal/v18/n6/full/3800351a.html http://www.nature.com/modpathol/journal/v18/n6/full/3800351a.html]. Accessed on: 9 December 2010.</ref>
*Alpha-inhibin +ve (cytoplasm).
*EMA -ve.
**RCC typically +ve.
*NSE +ve (nucleus + cytoplasm).
**RCC typically -ve.
*CK -ve.
==See also==
*[[Von Hippel-Lindau disease]].
*[[Neuropathology tumours]].
*[[Hemangioblastoma of the kidney]].
==References==
{{Reflist|2}}
[[Category:Diagnosis]]
[[Category:Neuropathology tumours]]
8fba6dc1764a8271980eef58d64fc446d82ee4ef5a45c644fef1378d0a1cbf76 librepath-hemangioblastoma.txt
{{ Infobox diagnosis
| Name = {{PAGENAME}}
| Image = Capillary_hemangioma_-_very_high_mag.jpg
| Width =
| Caption = Capillary hemangioma. [[H&E stain]].
| Micro = channels lined by benign endothelium containing [[RBC]]s
| Subtypes = soft tissue (capillary, cavernous, arteriovenous, venous, intramuscular, synovial), childhood (tufted, microvenular hemangioma, glomeruloid hemangioma, epithelioid hemangioma (see [[angiolymphoid hyperplasia with eosinophilia‎]]), targetoid hemosideric hemangioma, infantile hemangioma)
| LMDDx = [[lymphangioma]], [[angiokeratoma]], [[lobular capillary hemangioma]] (pyogenic granuloma).
| Stains =
| IHC = CD31 +ve, D2-40 -ve, GLUT-1 +ve -- juvenile hemangioma
| EM =
| Molecular =
| IF =
| Gross =
| Grossing =
| Site = [[soft tissue]], [[skin]], [[liver hemangioma|liver]] (dealt with in separate article), others
| Assdx = [[Castleman disease]] - for glomeruloid hemangioma
| Syndromes = [[POEMS syndrome]] - for glomeruloid hemangioma, [[Maffucci's syndrome]]
| Clinicalhx =
| Signs =
| Symptoms =
| Prevalence = common vascular lesion
| Bloodwork =
| Rads =
| Endoscopy =
| Prognosis = benign
| Other =
| ClinDDx =
}}
{{ Infobox external links
| Name = Hemangioma
| EHVSC = 10172
| pathprotocols =
| wikipedia =
| pathoutlines =
}}
'''Hemangioma''' is a very common benign [[vascular tumour]].