Archive 1 checkpoints (1-1)
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paper-releases/pbisc-diffusion/updates/20261004T165054Z-rare-states-screen/diffusion/metadata/NOTE.md
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# PBISC-diffusion update 20261004T165054Z-rare-states-screen
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Rare disease-associated states beyond C1Q-high monocytes (plans/rare_states_screen_20261004, 2026-10-05): literature-based marker rules for 15 states scored on the existing zero-shot cross-disease arms (DRESS in corpus; Kawasaki, SLE GSE135779 not in corpus; final f01 6k E16, no new generation) and on the corpus sample. Reproduced with disease direction: Kawasaki MS1 (IL1R2+) monocytes (gen/obs 0.67), SLE ISG-high T (Spearman 0.86), SLE cycling T/NK (0.85x). Compressed: plasmablasts, C1Q-high (0.1-0.25x). Not generated: DN2/ABC B (0.08x), granulocyte-like/LDG (0.007-0.09x) although present in the corpus. Code, state rules, README, tables, logs.
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Payload states are recorded as supplied. Inference locations are pointers, not archived generated outputs.
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