Archive 4 checkpoints (1-4)
Browse files- paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/geneset_feature_qc.json +36 -0
- paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/inputs/inputs_manifest.json +0 -0
- paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/prepared.json +24 -0
- paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/run_manifest.json +103 -0
paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/geneset_feature_qc.json
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{
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"run_signature": "8927b9166cd6e332a8e35708cc1fe9711f00c9e4fbd5f4f4d58e4936ae1f319f",
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"selected_gene_sets": 727,
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"reps": {
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"HS40": {
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"n_cells": 3867,
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"median_thresholded_gene_library": 8911.7646484375,
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"median_nonzero_genes": 147.0,
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"zero_score_pathways": 122
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},
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"HS30": {
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"n_cells": 6447,
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"median_thresholded_gene_library": 8900.81640625,
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"median_nonzero_genes": 140.0,
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"zero_score_pathways": 157
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},
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"HS53": {
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"n_cells": 1544,
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"median_thresholded_gene_library": 8720.443359375,
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"median_nonzero_genes": 135.0,
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"zero_score_pathways": 208
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},
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"HS39": {
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"n_cells": 2056,
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"median_thresholded_gene_library": 8802.19140625,
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"median_nonzero_genes": 140.0,
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"zero_score_pathways": 198
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},
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"HS109": {
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"n_cells": 4265,
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"median_thresholded_gene_library": 8649.681640625,
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"median_nonzero_genes": 148.0,
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"zero_score_pathways": 143
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}
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}
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}
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paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/inputs/inputs_manifest.json
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paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/prepared.json
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{
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"run_signature": "8927b9166cd6e332a8e35708cc1fe9711f00c9e4fbd5f4f4d58e4936ae1f319f",
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"seconds": 24.7,
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"files": {
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"processed_bulkdata.h5ad": "5d9849e30011ccf6b152144c411fc033e37449a96ef6fdcfca433733c668be9d",
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"hvgenes.npy": "715acc5606562dab7b9404ca256a69bcb462758189ce3582d80d867fe04eca60",
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"sids.txt": "e59929ea2a2e736db3c3592a8f6fa66a979a368c643dcd374c9d02a042f9e7c3",
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"hvset.npy": "fe1a973eed15cb195e77f923e9847c92a850e6fc685b3e31367112c4def1ae0e",
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"hvmask.npy": "3e426aa09b0c4573cb9c197d96c9525c86671bb5fe57b5df31d42f0704393751",
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"status/init_representatives.txt": "a6f5276de80cdf6650a9432b26b1aa86061f0a780e5c30cee0a5ad297804606c",
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"status/init_cluster_labels.txt": "9d040d2e601812ef872f0ad09ad5c4e5819550a6e0e6b37772966d979d5e55e5",
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"sample_sc/HS40.h5ad": "c2d6f8f9ba475f2d741eaee91e06741b07bff3eac0e8c0543c291f2e3e018415",
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"sample_sc/HS30.h5ad": "200b8d9d202371b64278056e8b51108267e3cc47a6ee94c5c5e523cf391a763a",
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"sample_sc/HS53.h5ad": "303bb684d1339009d9059c79bffd23f3b1cbfbdaa961934a3f15a485f01acf6f",
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"sample_sc/HS39.h5ad": "a32bc4cfb15e18aa3d8e9299ff5b11b2fb906f7262e5984dc141b873dec47f28",
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"sample_sc/HS109.h5ad": "9ad6b70a37439ac1956e5d8dc481d746a0311e4c23d81f07f49231e1141e3fe3",
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"geneset_scores/HS40.npy": "a2f33022e7c3f4468dfe00ab3ccc7170252a000a814ad94d836ca7cab73e73db",
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"geneset_scores/HS30.npy": "060e98fc0e69ca9148eee28e7ad266ba30eda1e70fc996ecf640944b0c47ff02",
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"geneset_scores/HS53.npy": "edfdf5d3e97531cf123422e0197093a037159e1203e194a7c0317e0d9e7dbc4e",
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"geneset_scores/HS39.npy": "428f3b7c8756bd70eea495560f5c7907145e7839e1386bac47dd46f7fe43ecbe",
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"geneset_scores/HS109.npy": "a2a8a07578b2f90afd6ead5d330ba9343f6204896ebae4c9ab83f3e54e12a605"
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},
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"genesets_gmt_sha256": "9c4386ac1ff666fc88301e126f1a1c6452122c6b63f311131a640bffe9c4d84b"
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}
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paper-releases/pbisc-diffusion/updates/20261012T130738Z-strictpairs-implementation/diffusion/dataset/server_1/model8/plans/paper_figures_strictpairs_20261012/archive/20261012T130738Z-strictpairs-implementation/snapshot/scsemi/immicro/healthy/fold0/n5/run_manifest.json
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{
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"run_signature": "8927b9166cd6e332a8e35708cc1fe9711f00c9e4fbd5f4f4d58e4936ae1f319f",
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| 3 |
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"protocol": {
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"method": "scSemiProfiler",
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"setting": "paired_fixed_representatives_realbulk_genesets",
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"upstream_commit": "c2aea021188759e56ecf14578915c0237aaa75d2",
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"initsetup": {
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"logged": false,
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"normed": false,
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"geneselection": false,
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"batch": 1
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},
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"scprocess": {
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"logged": false,
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"normed": false,
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"cellfilter": false,
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"threshold": 0.001,
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"geneset": true,
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"weight": 0.5,
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"k": 15
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},
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"representatives": "fixed: every usable row of the split's training donors (no active learning)",
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"assignment": "upstream representative_selection.update_membership: nearest representative by Euclidean distance in processed_bulkdata.obsm['X_pca'] (initsetup PCA of log1p CP10K real bulk)",
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"pretrain1": {
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"vaesteps": 100,
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| 26 |
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"gansteps": 100,
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"lr": 0.001,
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"k": 15,
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"diagw": 1
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},
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"pretrain2": {
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"vaesteps": 50,
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"gansteps": 50,
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"lr": 0.0001,
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| 35 |
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"k": 15,
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| 36 |
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"diagw": 1.0
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},
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| 38 |
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"infer": {
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| 39 |
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"bulktype": "real",
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| 40 |
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"pseudocount": 0.1,
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| 41 |
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"lr": 0.0002,
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| 42 |
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"epochs": 150,
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| 43 |
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"ministages": 5,
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| 44 |
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"k": 15,
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| 45 |
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"diagw": 1.0
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| 46 |
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},
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| 47 |
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"seeds": {
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| 48 |
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"base": 20260927,
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| 49 |
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"pretrain1": "base + 1000 + bulk row index",
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| 50 |
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"pretrain2": "base + 2000 + bulk row index",
|
| 51 |
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"target": "base + bulk row index (frozen campaign rule)"
|
| 52 |
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},
|
| 53 |
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"output_unit": "normalized_expression (upstream fast_semi output: ZINB mean, rep-cell library, values <= 10 zeroed)",
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| 54 |
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"cellgraph_impl": "tools/lean_cellgraph.fast_cellgraph_lean replaces upstream singlecell_process.fast_cellgraph inside scprocess: same arithmetic, chunked (16 GiB CPU cap); bit-identical outputs verified (validation/lean_cellgraph_*.json)",
|
| 55 |
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"scprocess_orchestration": "cohort hvset first (upstream scprocess's own steps: sorted sample_ids, normalize_total 1e4, dense, X*(X>10), getGeneSetMatrix score formula, concatenate, log1p, highly_variable_genes) -> hvset.npy; then upstream scprocess once per representative (it skips hvset when hvset.npy exists). Bit-identical to one scprocess call over all representatives (validation/prepared_*.json); peak memory is one representative",
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| 56 |
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"hvset_impl": "tools/lean_hvset.cohort_hvset_lean: streamed, one representative in memory; output-identical to cohort_hvset (validation/hvset_dependence_20261002.json)"
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| 57 |
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},
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| 58 |
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"inputs": {
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| 59 |
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"bulk.h5ad": "af8a9cf8384a065c43c20b8ec9520710ce5d4f5b5b9702f22063e09c70695663",
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"rep_sc.h5ad": "ab00c585b03386a898ea9564e25d1e41ea10f818830065317e05297f41d29b87"
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| 61 |
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},
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| 62 |
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"source": {
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| 63 |
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"repository": "https://github.com/mcgilldinglab/scSemiProfiler",
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| 64 |
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"commit": "c2aea021188759e56ecf14578915c0237aaa75d2",
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"compatibility_patch_sha256": "314d353002ffb482b4ed4b61a32b280a50ff8b6a9933512ada9fdc74c17b1711",
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| 66 |
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"changes": [
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| 67 |
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"remove unused scvi.nn.one_hot import",
|
| 68 |
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"translate legacy use_gpu to accelerator/devices",
|
| 69 |
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"avoid empty slice when geneset_len is zero",
|
| 70 |
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"drop a size-1 trailing training batch: scvi DataSplitter(drop_last=True) only when n_obs % batch_size == 1 (upstream's own commented-out remedy); all other cell counts unchanged"
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| 71 |
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],
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| 72 |
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"files": {
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},
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"environment": {
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"torch": "2.11.0+cu130",
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"scvi-tools": "1.4.1",
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"scanpy": "1.11.5",
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"anndata": "0.12.19",
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"lightning": "2.6.6",
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"numpy": "2.5.3",
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| 93 |
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"scikit-learn": "1.9.1",
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"gseapy": "1.3.0"
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"wrapper_sha256": "24d36efb13500e9d555bcdf19976dea575f9710fd0a25c68fae836f51723fc7f",
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"lean_cellgraph_sha256": "0de823e4475786fcd86c0fb83302182ffebafe00a1dad44cdcccc99938430230",
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"geneset_mapped_gmt_sha256": "9c4386ac1ff666fc88301e126f1a1c6452122c6b63f311131a640bffe9c4d84b",
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"lean_hvset_sha256": "3783f6e9728c3ecdb41ec6068f15bc9bf44ff5fc25644ca0e8734c1981486e86",
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| 101 |
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"work": "/home/sj_server_1/PBISC/immun-pbmc-fm/model_8_sparse_data_diffusion/plans/paper_figures_strictpairs_20261012/scsemi/immicro/healthy/fold0/n5",
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| 102 |
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"hostname": "spark-fa6b"
|
| 103 |
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}
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