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BenchRep-T

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tcr-beta
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AIRR
immunoseq
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1
lordim commited on
Commit
e34b692
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1 Parent(s): a4fa97f

Remove old immunoSEQ dirs (renamed to Savola_RA / Musvosvi_TB)

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  1. immunoSEQ/rheumatoid_arthritis/metadata.tsv +0 -92
  2. immunoSEQ/rheumatoid_arthritis/repertoires/HC1.tsv.gz +0 -3
  3. immunoSEQ/rheumatoid_arthritis/repertoires/HC10.tsv.gz +0 -3
  4. immunoSEQ/rheumatoid_arthritis/repertoires/HC11.tsv.gz +0 -3
  5. immunoSEQ/rheumatoid_arthritis/repertoires/HC12.tsv.gz +0 -3
  6. immunoSEQ/rheumatoid_arthritis/repertoires/HC13.tsv.gz +0 -3
  7. immunoSEQ/rheumatoid_arthritis/repertoires/HC14.tsv.gz +0 -3
  8. immunoSEQ/rheumatoid_arthritis/repertoires/HC15.tsv.gz +0 -3
  9. immunoSEQ/rheumatoid_arthritis/repertoires/HC16.tsv.gz +0 -3
  10. immunoSEQ/rheumatoid_arthritis/repertoires/HC17.tsv.gz +0 -3
  11. immunoSEQ/rheumatoid_arthritis/repertoires/HC18.tsv.gz +0 -3
  12. immunoSEQ/rheumatoid_arthritis/repertoires/HC19.tsv.gz +0 -3
  13. immunoSEQ/rheumatoid_arthritis/repertoires/HC2.tsv.gz +0 -3
  14. immunoSEQ/rheumatoid_arthritis/repertoires/HC20.tsv.gz +0 -3
  15. immunoSEQ/rheumatoid_arthritis/repertoires/HC3.tsv.gz +0 -3
  16. immunoSEQ/rheumatoid_arthritis/repertoires/HC4.tsv.gz +0 -3
  17. immunoSEQ/rheumatoid_arthritis/repertoires/HC5.tsv.gz +0 -3
  18. immunoSEQ/rheumatoid_arthritis/repertoires/HC6.tsv.gz +0 -3
  19. immunoSEQ/rheumatoid_arthritis/repertoires/HC7.tsv.gz +0 -3
  20. immunoSEQ/rheumatoid_arthritis/repertoires/HC8.tsv.gz +0 -3
  21. immunoSEQ/rheumatoid_arthritis/repertoires/HC9.tsv.gz +0 -3
  22. immunoSEQ/rheumatoid_arthritis/repertoires/RA1-7months.tsv.gz +0 -3
  23. immunoSEQ/rheumatoid_arthritis/repertoires/RA1.tsv.gz +0 -3
  24. immunoSEQ/rheumatoid_arthritis/repertoires/RA10.tsv.gz +0 -3
  25. immunoSEQ/rheumatoid_arthritis/repertoires/RA11.tsv.gz +0 -3
  26. immunoSEQ/rheumatoid_arthritis/repertoires/RA12.tsv.gz +0 -3
  27. immunoSEQ/rheumatoid_arthritis/repertoires/RA13.tsv.gz +0 -3
  28. immunoSEQ/rheumatoid_arthritis/repertoires/RA14.tsv.gz +0 -3
  29. immunoSEQ/rheumatoid_arthritis/repertoires/RA15.tsv.gz +0 -3
  30. immunoSEQ/rheumatoid_arthritis/repertoires/RA16.tsv.gz +0 -3
  31. immunoSEQ/rheumatoid_arthritis/repertoires/RA17.tsv.gz +0 -3
  32. immunoSEQ/rheumatoid_arthritis/repertoires/RA18.tsv.gz +0 -3
  33. immunoSEQ/rheumatoid_arthritis/repertoires/RA19.tsv.gz +0 -3
  34. immunoSEQ/rheumatoid_arthritis/repertoires/RA2-18months.tsv.gz +0 -3
  35. immunoSEQ/rheumatoid_arthritis/repertoires/RA2.tsv.gz +0 -3
  36. immunoSEQ/rheumatoid_arthritis/repertoires/RA20.tsv.gz +0 -3
  37. immunoSEQ/rheumatoid_arthritis/repertoires/RA21.tsv.gz +0 -3
  38. immunoSEQ/rheumatoid_arthritis/repertoires/RA22.tsv.gz +0 -3
  39. immunoSEQ/rheumatoid_arthritis/repertoires/RA23-CD4.tsv.gz +0 -3
  40. immunoSEQ/rheumatoid_arthritis/repertoires/RA23-SF-CD8.tsv.gz +0 -3
  41. immunoSEQ/rheumatoid_arthritis/repertoires/RA23.tsv.gz +0 -3
  42. immunoSEQ/rheumatoid_arthritis/repertoires/RA24.tsv.gz +0 -3
  43. immunoSEQ/rheumatoid_arthritis/repertoires/RA25.tsv.gz +0 -3
  44. immunoSEQ/rheumatoid_arthritis/repertoires/RA26.tsv.gz +0 -3
  45. immunoSEQ/rheumatoid_arthritis/repertoires/RA28.tsv.gz +0 -3
  46. immunoSEQ/rheumatoid_arthritis/repertoires/RA29.tsv.gz +0 -3
  47. immunoSEQ/rheumatoid_arthritis/repertoires/RA3-3years.tsv.gz +0 -3
  48. immunoSEQ/rheumatoid_arthritis/repertoires/RA3.tsv.gz +0 -3
  49. immunoSEQ/rheumatoid_arthritis/repertoires/RA30.tsv.gz +0 -3
  50. immunoSEQ/rheumatoid_arthritis/repertoires/RA31.tsv.gz +0 -3
immunoSEQ/rheumatoid_arthritis/metadata.tsv DELETED
@@ -1,92 +0,0 @@
1
- participant_label specimen_label disease CV_fold sample_name total_templates productive_templates fraction_productive total_rearrangements productive_rearrangements productive_simpson_clonality max_productive_frequency locus sample_tags sku test_name disease_label fold
2
- RA3 RA3-3years Rheumatoid Arthritis 1 RA3-3years 75878 47734 0.6291 7430 5972 0.5121 0.471969664 TCRB Rheumatoid Arthritis 1
3
- RA1 RA1-7months Rheumatoid Arthritis 0 RA1-7months 35540 33704 0.9483 3203 2573 0.4794 0.412324935 TCRB Rheumatoid Arthritis 0
4
- RA2 RA2-18months Rheumatoid Arthritis 1 RA2-18months 28806 21808 0.7571 9438 7708 0.1203 0.078182317 TCRB Rheumatoid Arthritis 1
5
- HC8 HC8 Healthy 2 HC8 39179 33080 0.8443 17992 15060 0.0449 0.026844015 TCRB Healthy 2
6
- HC9 HC9 Healthy 0 HC9 44432 37343 0.8405 18793 15101 0.0658 0.0302868 TCRB Healthy 0
7
- HC11 HC11 Healthy 2 HC11 72573 60197 0.8295 52076 43148 0.0147 0.005515225 TCRB Healthy 2
8
- HC17 HC17 Healthy 2 HC17 62214 52286 0.8404 36228 30233 0.0724 0.070841141 TCRB Healthy 2
9
- HC10 HC10 Healthy 2 HC10 63549 52695 0.8292 39422 32642 0.03 0.01700351 TCRB Healthy 2
10
- HC18 HC18 Healthy 2 HC18 76101 67056 0.8811 17149 14062 0.1857 0.120317347 TCRB Healthy 2
11
- HC19 HC19 Healthy 1 HC19 54855 48119 0.8772 10221 8392 0.2195 0.175419271 TCRB Healthy 1
12
- HC20 HC20 Healthy 1 HC20 80658 70698 0.8765 24415 21190 0.1034 0.071175985 TCRB Healthy 1
13
- RA72 RA72 Rheumatoid Arthritis 1 RA72 39291 32459 0.8261 20728 17155 0.0369 0.017221727 TCRB Rheumatoid Arthritis 1
14
- RA74 RA74 Rheumatoid Arthritis 2 RA74 53976 41035 0.7602 19501 15778 0.0801 0.035067625 TCRB Rheumatoid Arthritis 2
15
- RA75 RA75 Rheumatoid Arthritis 0 RA75 83754 71293 0.8512 28084 23299 0.0904 0.047367904 TCRB Rheumatoid Arthritis 0
16
- RA76 RA76 Rheumatoid Arthritis 2 RA76 60117 47526 0.7906 36846 29130 0.022 0.009405378 TCRB Rheumatoid Arthritis 2
17
- RA79 RA79 Rheumatoid Arthritis 0 RA79 12823 9414 0.7341 3915 2947 0.1831 0.103462927 TCRB Rheumatoid Arthritis 0
18
- RA80 RA80 Rheumatoid Arthritis 0 RA80 51626 40409 0.7827 27094 21578 0.0454 0.019970799 TCRB Rheumatoid Arthritis 0
19
- RA24 RA24 Rheumatoid Arthritis 0 RA24 56170 43267 0.7703 24672 19894 0.0803 0.053112071 TCRB HLA MHC Class I Rheumatoid Arthritis 0
20
- RA81 RA81 Rheumatoid Arthritis 2 RA81 55697 44532 0.7995 12628 10224 0.2089 0.191008717 TCRB Rheumatoid Arthritis 2
21
- RA82 RA82 Rheumatoid Arthritis 2 RA82 52313 43742 0.8362 21259 17824 0.1416 0.112454847 TCRB Rheumatoid Arthritis 2
22
- RA25 RA25 Rheumatoid Arthritis 0 RA25 48192 38011 0.7887 29017 23956 0.0525 0.042145696 TCRB HLA MHC Class I Rheumatoid Arthritis 0
23
- HC12 HC12 Healthy 0 HC12 59854 46310 0.7737 33309 26574 0.0896 0.062275965 TCRB Healthy 0
24
- HC13 HC13 Healthy 1 HC13 58937 48579 0.8243 30677 24398 0.0557 0.045884024 TCRB Healthy 1
25
- HC14 HC14 Healthy 0 HC14 51995 43104 0.829 18387 14697 0.0522 0.02419729 TCRB Healthy 0
26
- HC15 HC15 Healthy 1 HC15 54821 46599 0.85 10997 8848 0.1345 0.070774049 TCRB Healthy 1
27
- HC16 HC16 Healthy 0 HC16 52699 44264 0.8399 30554 24518 0.1233 0.110654257 TCRB Healthy 0
28
- RA52 RA52 Rheumatoid Arthritis 0 RA52 59096 47929 0.811 24437 19753 0.047 0.018569134 TCRB Rheumatoid Arthritis 0
29
- RA53 RA53 Rheumatoid Arthritis 2 RA53 70454 54870 0.7788 21325 17200 0.1306 0.10703481 TCRB Rheumatoid Arthritis 2
30
- RA54 RA54 Rheumatoid Arthritis 0 RA54 51840 44091 0.8505 30411 25115 0.0663 0.051439069 TCRB Rheumatoid Arthritis 0
31
- RA55 RA55 Rheumatoid Arthritis 0 RA55 61136 50929 0.833 42388 35951 0.0355 0.018358892 TCRB Rheumatoid Arthritis 0
32
- RA56 RA56 Rheumatoid Arthritis 1 RA56 43010 35000 0.8138 25652 20638 0.0245 0.007771429 TCRB Rheumatoid Arthritis 1
33
- RA57 RA57 Rheumatoid Arthritis 0 RA57 56052 47002 0.8385 22378 18376 0.0508 0.027296711 TCRB HLA MHC Class I Rheumatoid Arthritis 0
34
- RA58 RA58 Rheumatoid Arthritis 2 RA58 64146 49475 0.7713 29954 23176 0.0719 0.052915614 TCRB Rheumatoid Arthritis 2
35
- RA59 RA59 Rheumatoid Arthritis 0 RA59 66756 55699 0.8344 33866 28052 0.0439 0.021059625 TCRB Rheumatoid Arthritis 0
36
- RA60 RA60 Rheumatoid Arthritis 0 RA60 54366 44672 0.8217 14043 11225 0.1358 0.068476901 TCRB Rheumatoid Arthritis 0
37
- RA62 RA62 Rheumatoid Arthritis 2 RA62 31076 25219 0.8115 11805 9437 0.1664 0.136325791 TCRB Rheumatoid Arthritis 2
38
- RA63 RA63 Rheumatoid Arthritis 2 RA63 13973 11527 0.8249 6021 4849 0.1035 0.077296779 TCRB HLA MHC Class I Rheumatoid Arthritis 2
39
- RA65 RA65 Rheumatoid Arthritis 0 RA65 53130 41478 0.7807 25467 20986 0.1081 0.089131586 TCRB Rheumatoid Arthritis 0
40
- RA66 RA66 Rheumatoid Arthritis 0 RA66 66158 47892 0.7239 17399 14244 0.2557 0.249979123 TCRB Rheumatoid Arthritis 0
41
- RA68 RA68 Rheumatoid Arthritis 1 RA68 53389 40992 0.7678 22965 18647 0.0686 0.046496876 TCRB Rheumatoid Arthritis 1
42
- RA70 RA70 Rheumatoid Arthritis 2 RA70 21533 18161 0.8434 10739 8951 0.0496 0.03452453 TCRB Rheumatoid Arthritis 2
43
- RA26 RA26 Rheumatoid Arthritis 1 RA26 22095 18318 0.8291 13960 11447 0.0248 0.012228409 TCRB Rheumatoid Arthritis 1
44
- RA28 RA28 Rheumatoid Arthritis 1 RA28 21922 17544 0.8003 15765 12934 0.0302 0.014534884 TCRB Rheumatoid Arthritis 1
45
- RA29 RA29 Rheumatoid Arthritis 1 RA29 52896 44767 0.8463 27553 22765 0.1981 0.194495946 TCRB Rheumatoid Arthritis 1
46
- RA30 RA30 Rheumatoid Arthritis 1 RA30 19341 15647 0.809 8327 6692 0.1211 0.084872499 TCRB Rheumatoid Arthritis 1
47
- RA31 RA31 Rheumatoid Arthritis 0 RA31 9050 7501 0.8288 6286 5239 0.0296 0.011865085 TCRB Rheumatoid Arthritis 0
48
- RA32 RA32 Rheumatoid Arthritis 1 RA32 26643 22193 0.833 15518 12822 0.0618 0.051908258 TCRB Rheumatoid Arthritis 1
49
- RA33 RA33 Rheumatoid Arthritis 2 RA33 38973 30972 0.7947 11505 8855 0.0912 0.060893711 TCRB HLA MHC Class I Rheumatoid Arthritis 2
50
- RA37 RA37 Rheumatoid Arthritis 1 RA37 4997 3818 0.7641 2357 1814 0.0662 0.026191723 TCRB Rheumatoid Arthritis 1
51
- RA40 RA40 Rheumatoid Arthritis 2 RA40 33820 27801 0.822 6674 5274 0.2087 0.112082303 TCRB Rheumatoid Arthritis 2
52
- RA41 RA41 Rheumatoid Arthritis 2 RA41 11912 9503 0.7978 8701 6974 0.0228 0.009681153 TCRB Rheumatoid Arthritis 2
53
- RA46 RA46 Rheumatoid Arthritis 2 RA46 59376 47163 0.7943 23872 19708 0.0729 0.031847 TCRB HLA MHC Class I Rheumatoid Arthritis 2
54
- RA47 RA47 Rheumatoid Arthritis 2 RA47 56908 46422 0.8157 20130 16724 0.0787 0.054801602 TCRB Rheumatoid Arthritis 2
55
- RA48 RA48 Rheumatoid Arthritis 2 RA48 50271 41455 0.8246 28549 23409 0.0421 0.032493066 TCRB Rheumatoid Arthritis 2
56
- RA49 RA49 Rheumatoid Arthritis 0 RA49 74000 60969 0.8239 44609 37700 0.0348 0.018320786 TCRB HLA MHC Class I Rheumatoid Arthritis 0
57
- RA50 RA50 Rheumatoid Arthritis 1 RA50 69969 61826 0.8836 23914 20397 0.088 0.0505936 TCRB Rheumatoid Arthritis 1
58
- RA51 RA51 Rheumatoid Arthritis 1 RA51 56067 47615 0.8493 16950 14096 0.1558 0.081444919 TCRB Rheumatoid Arthritis 1
59
- HC7 HC7 Healthy 1 HC7 59627 50923 0.854 25521 20303 0.0766 0.043753505 TCRB "CD8+, Peripheral blood lymphocytes (PBL), T cells" Healthy 1
60
- HC6 HC6 Healthy 1 HC6 57125 45559 0.7975 21558 17217 0.0852 0.041231256 TCRB "CD8+, Peripheral blood lymphocytes (PBL), T cells" Healthy 1
61
- HC5 HC5 Healthy 1 HC5 59340 41190 0.6941 13375 10959 0.256 0.24665913 TCRB "CD8+, Peripheral blood lymphocytes (PBL), T cells" Healthy 1
62
- HC4 HC4 Healthy 0 HC4 69944 58236 0.8326 20493 16518 0.0887 0.053772524 TCRB "CD8+, Peripheral blood lymphocytes (PBL), T cells" Healthy 0
63
- HC3 HC3 Healthy 2 HC3 63066 56523 0.8963 16464 13774 0.2668 0.259920627 TCRB "CD8+, Peripheral blood lymphocytes (PBL), T cells" Healthy 2
64
- HC2 HC2 Healthy 0 HC2 72691 58930 0.8107 36962 29818 0.0226 0.007905783 TCRB "CD8+, Peripheral blood lymphocytes (PBL), T cells" Healthy 0
65
- HC1 HC1 Healthy 0 HC1 83507 64572 0.7733 13194 10687 0.1736 0.118211403 TCRB "CD8+, Peripheral blood lymphocytes (PBL), T cells" Healthy 0
66
- RA23 RA23-SF-CD8 Rheumatoid Arthritis 1 RA23-SF-CD8 18828 15415 0.8187 5754 4599 0.0716 0.041477062 TCRB "CD8+, Rheumatoid Arthritis, Synovial fluid, T cells" Rheumatoid Arthritis 1
67
- RA23 RA23 Rheumatoid Arthritis 1 RA23 7747 6575 0.8487 5910 4766 0.084 0.057873074 TCRB "CD8+, Peripheral blood lymphocytes (PBL), Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
68
- RA23 RA23-CD4 Rheumatoid Arthritis 1 RA23-CD4 23735 19531 0.8229 21125 17042 0.0114 0.005459813 TCRB "CD4+, Peripheral blood lymphocytes (PBL), Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
69
- RA22 RA22 Rheumatoid Arthritis 2 RA22 49444 38110 0.7708 21309 17226 0.0965 0.069929116 TCRB "CD8+, HLA MHC Class I, Peripheral blood lymphocytes (PBL), Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 2
70
- RA21 RA21 Rheumatoid Arthritis 0 RA21 62622 50032 0.799 39430 31137 0.0415 0.029714275 TCRB "CD8+, Peripheral blood lymphocytes (PBL), Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 0
71
- RA20 RA20 Rheumatoid Arthritis 0 RA20 20607 15320 0.7434 4680 3691 0.2213 0.162258536 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 0
72
- RA19 RA19 Rheumatoid Arthritis 2 RA19 11341 9389 0.8279 6587 5276 0.1039 0.079631694 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 2
73
- RA18 RA18 Rheumatoid Arthritis 1 RA18 6595 3788 0.5744 2212 1620 0.1621 0.101727076 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
74
- RA17 RA17 Rheumatoid Arthritis 2 RA17 7396 6164 0.8334 2966 2314 0.2747 0.202736616 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 2
75
- RA15 RA15 Rheumatoid Arthritis 1 RA15 31027 25964 0.8368 20563 16521 0.0685 0.045264199 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
76
- RA13 RA13 Rheumatoid Arthritis 2 RA13 27140 21465 0.7909 9311 7317 0.1334 0.091548055 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 2
77
- RA12 RA12 Rheumatoid Arthritis 0 RA12 25115 18714 0.7451 6783 5350 0.228 0.157300845 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 0
78
- RA6 RA6-SF Rheumatoid Arthritis 1 RA6-SF 2806 2204 0.7855 1529 1175 0.0914 0.060221322 TCRB "Rheumatoid Arthritis, Synovial fluid" Rheumatoid Arthritis 1
79
- RA6 RA6-CD4 Rheumatoid Arthritis 1 RA6-CD4 38308 32821 0.8568 28134 22891 0.0969 0.064752638 TCRB "CD8-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
80
- RA6 RA6 Rheumatoid Arthritis 1 RA6 35569 29574 0.8315 9525 7650 0.2096 0.111250617 TCRB "CD4-, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
81
- RA5 RA5 Rheumatoid Arthritis 2 RA5 46735 40218 0.8606 11228 8895 0.3024 0.290390968 TCRB "CD8+, T Cell Large Granular Lymphocyte Leukemia (LGL), T cells" Rheumatoid Arthritis 2
82
- RA16 RA16 Rheumatoid Arthritis 2 RA16 12844 9993 0.778 6295 4858 0.1333 0.067450158 TCRB "CD8+, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 2
83
- RA4 RA4 Rheumatoid Arthritis 0 RA4 28409 19607 0.6902 15465 12345 0.1566 0.132319644 TCRB "CD8+, HLA MHC Class I, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 0
84
- RA3 RA3 Rheumatoid Arthritis 1 RA3 39504 23246 0.5884 7216 5707 0.5259 0.510262191 TCRB "CD8+, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
85
- RA10 RA10 Rheumatoid Arthritis 1 RA10 17832 11947 0.67 4363 3403 0.2496 0.161554158 TCRB "CD8+, HLA MHC Class I, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
86
- RA2 RA2 Rheumatoid Arthritis 1 RA2 16162 12604 0.7799 8307 6630 0.1339 0.078126013 TCRB "CD8+, HLA MHC Class I, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
87
- RA9 RA9 Rheumatoid Arthritis 0 RA9 25652 22457 0.8754 14528 11894 0.2056 0.171679258 TCRB "CD8+, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 0
88
- RA1 RA1 Rheumatoid Arthritis 0 RA1 33857 32028 0.946 4757 3788 0.4576 0.339007616 TCRB "CD8+, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 0
89
- RA7 RA7 Rheumatoid Arthritis 1 RA7 17120 11917 0.6961 5711 4329 0.2015 0.137814626 TCRB "CD8+, HLA MHC Class I, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
90
- RA8 RA8 Rheumatoid Arthritis 1 RA8 9206 7397 0.8035 7996 6333 0.0356 0.019681411 TCRB "CD8+, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 1
91
- RA14 RA14 Rheumatoid Arthritis 2 RA14 7846 5777 0.7363 4840 3683 0.1116 0.079763874 TCRB "CD8+, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 2
92
- RA11 RA11 Rheumatoid Arthritis 0 RA11 26221 22126 0.8438 9713 7976 0.2986 0.27503103 TCRB "CD8+, Rheumatoid Arthritis, T cells" Rheumatoid Arthritis 0
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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