| --- |
| license: apache-2.0 |
| tags: |
| - biology |
| size_categories: |
| - 1B<n<10B |
| --- |
| |
| # Dataset Card for GuideRNA-3B |
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| ## Dataset Description |
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| - **Homepage:** https://github.com/bm2-lab/CRISPR-viva |
| - **Repository:** https://github.com/bm2-lab/CRISPR-viva |
| - **Contact:** 18alexanderm117@tongji.edu.cn |
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| ### Dataset Summary |
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| **GuideRNA-3B** is a large transcriptome sequence corpus consisting of over 3.7 billion paired sequences extracted from the specific transcriptome of 23 cell lines and over 200 segmented genomes of RNA virus. |
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| ### Supported Tasks |
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| Based on this nucleotide sequence corpus, we are able to establish a foundation model to characterize the manifold of CRISPR guide RNA targeting regions in order to undertake further downstreaming task for universal CRISPR-based RNA virus amplification-free detection and inhibition. |
| For details, please refer to [our paper](https://github.com/bm2-lab/CRISPR-viva) and [website](https://github.com/bm2-lab/CRISPR-viva). |
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| ### Languages |
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| English (en). |
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| ## Dataset Structure |
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| ### jsonl-based Arrow |
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| These files are compressed Arrow-formated sourced from JSON-lined text file data, with the following columns: |
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| - `before`: string. Nucleotide sequence from transcriptome of cell line or RNA virus. |
| - `next`: string. Nucleotide sequence with postion right-shifted by one. |
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| ### Citation Information |
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| If you find **GuideRNA-3B** helpful in your research, please cite our work by: |
