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meat-bro
Meat Bro
Predict the combined effects of pressure, hormone changes, arterial stiffness, and liver impairment.
# Meat Bro under pressure An adult male, nicknamed Meat Bro, is obese and has 50% more skeletal muscle than the reference adult male. He eats a normal diet. Both subjects have the same body composition, diet and 24-hour preparation before comparison time zero. Apply these changes together to the intervention subject ...
tasks/meat-bro
5
scenario-02
Summit Air Scrubber
Predict the combined effects of altitude, exercise, and altered breathing gas.
# Scenario 02 An adult male begins awake, resting and lying down at sea level in still air at 72°F (22.22°C), 30% relative humidity, wearing normal clothing. - At 0.1 min, the intervention subject sits and moves to an altitude of 1,000 m. - At 5.1 min, altitude becomes 2,000 m; at 10.1 min, it becomes 3,000 m. - At 1...
tasks/scenario-02
5
scenario-03
Rescue Basket
Predict responses to blood loss, cold, and head-up tilt.
# Scenario 03 An adult male begins awake, resting and lying down at sea level in still air at 72°F (22.22°C), 30% relative humidity, wearing normal clothing. - From 0.1 to 5.1 min, the intervention subject loses whole blood at a fixed 80 mL/min, totaling 400 mL. Bleeding is then stopped. No replacement fluid is giv...
tasks/scenario-03
5
scenario-07
Heart with a Shortcut
Predict exercise and recovery responses with weakened heart function and a vascular shunt.
# Scenario 07 An adult male has a shared 120-minute preparation before comparison time zero: - Both ventricular basic-contractility settings are set to 0.70 times their reference values and remain at that setting throughout. - During the first 30 min, whole blood is removed at 40 mL/min while an equal 40 mL/min o...
tasks/scenario-07
5
scenario-09
Robot Paramedic
Predict responses to saline and mechanical ventilation after blood loss with impaired kidney function.
# Scenario 09 An adult male has a shared 150-minute preparation before comparison time zero: - At the beginning of preparation, each kidney's filtering-nephron percentage is set to 50%, with total nephron counts unchanged. This setting is retained. - After 120 min, whole blood is removed at 50 mL/min for 15 min, to...
tasks/scenario-09
5
scenario-11
Shunt Shutdown
Predict the effects of closing a vascular shunt while changing adrenergic signaling and oxygen supply.
# Scenario 11 An adult male undergoes a shared 120-minute preparation. Both ventricular basic-contractility settings are 0.70 times their reference values. During the first 30 minutes, whole blood is removed at 40 mL/min and replaced with the same volume of plasma containing no red cells, totaling 1,200 mL exchanged. ...
tasks/scenario-11
5
scenario-12
Oxygen-Loop Fault
Predict hormonal and metabolic responses to mechanical ventilation with elevated oxygen and carbon dioxide.
# The Oxygen-Loop Fault An adult man at rest lies supine at sea level. For one hour, a breathing circuit supplies dry gas containing 60% oxygen, 1% carbon dioxide and 39% nitrogen. Mechanical ventilation delivers 8 breaths per minute with a tidal volume of 700 mL. Room temperature is 22.2 °C. Compare with the same man...
tasks/scenario-12
5
scenario-13
Centrifuge Saline Bag
Predict the combined effects of increased gravity, head-up tilt, supplemental oxygen, and saline.
# The Centrifuge Saline Bag An adult man at rest spends one hour restrained at 55 degrees head-up in a centrifuge producing an effective gravity of 1.5 g. He breathes dry 40% oxygen and 60% nitrogen at sea-level pressure and receives 500 mL of 0.9% saline evenly over the hour. Room temperature is 22.2 °C. Compare with...
tasks/scenario-13
5
scenario-16
Sealed Ambulance
Predict responses to concentrated saline and altered ventilation after blood loss with impaired kidney function.
# The Sealed Ambulance An adult man has half the usual number of filtering nephrons in each kidney. After two hours in this state, he loses 750 mL of whole blood evenly over 15 minutes and rests for 15 minutes after bleeding stops. He then spends one hour supine breathing dry 40% oxygen, 1% carbon dioxide and 59% nitr...
tasks/scenario-16
5
scenario-17
Cold Transfer
Predict the combined effects of cooling, head-up tilt, and supplemental oxygen.
# The Cold Transfer An adult man at rest starts supine in a 22.2 °C room, breathing ordinary air at sea-level pressure. At time zero, he is moved into a 15 °C room, restrained at 45 degrees head-up, and supplied dry 60% oxygen and 40% nitrogen. He remains under those conditions for one hour, without exercise, bleeding...
tasks/scenario-17
5

Physim Reasoning Tasks

Ten whole-body physiology tasks. Each task combines interventions across organ systems and asks an agent to predict five downstream changes relative to a matched simulated control.

The task catalog, model comparison, and project overview are available at symbolic.life/tasks.

Contents

  • tasks/: runnable Harbor tasks, each with an instruction, container environment, verifier, and reference solution.
  • task_catalog.jsonl: browsable task descriptions and prompts.
  • download/: the exact task archive served on symbolic.life.
  • benchmark-results.json: completed six-model benchmark results.

Run

Install Docker and uv, then run from this repository’s directory:

uv run --with harbor==0.23.0 python run_verified.py run --path ./tasks --agent oracle

To evaluate an agent, configure its provider credentials in your own environment and run:

uv run --with harbor==0.23.0 python run_verified.py run --path ./tasks --agent terminus-2 --model PROVIDER/MODEL --ak reasoning_effort=high

The supplied launcher uses the tested Harbor version and mounts each task’s verifier separately and read-only. Keep tests/ and solution/ outside the evaluated agent’s environment.

Scoring

The answer gives increase, decrease, or unchanged for each of five outputs. The task prompt specifies the comparison and unchanged threshold. Output accuracy is the fraction of correct directions; whole-task success requires all five directions to be correct.

Results

Each of the six models completed three attempts per task. The model identifiers and reasoning settings are recorded in benchmark-results.json. All recorded scores were independently regraded against the released task files.

Model Correct outputs Output accuracy Fully correct attempts
Claude Opus 5 73/150 48.7% 0/30
GPT-6 Astra 69/150 46.0% 0/30
Nemotron 3 Ultra 68/150 45.3% 0/30
Grok 4.6 66/150 44.0% 0/30
Gemini 3.8 Flash 63/150 42.0% 0/30
Grok 4.7 60/150 40.0% 0/30

Data source

Reference answers are frozen outputs of a physiological simulation. They are model predictions, rather than measured human outcomes. Running and grading the released tasks does not require access to the simulator or a GPU.

License

The task data, prompts, and included code are released under the Apache License 2.0.

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