QUEST-data / README.md
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---
license: cc-by-nc-nd-4.0
tags:
- pathology
- histopathology
- virtual-staining
- multiplex-immunofluorescence
extra_gated_heading: Request access to QUEST-data
extra_gated_prompt: >-
This dataset is released under CC BY-NC-ND 4.0 and may only be used for non-commercial
research with proper attribution. Any commercial use, sale or other monetisation of the
data or of models trained on it is prohibited and requires prior approval. The primary
email of your Hugging Face account must match your institutional email: requests from
free providers (@gmail, @outlook, @hotmail, @qq, @163, @foxmail and the like) are denied.
By downloading the data you attest that all information given below is correct and
up-to-date, and you agree not to distribute, publish, redistribute or reproduce a copy of
this dataset in whole or in part. If another user in your organisation wishes to use it,
they must register as an individual user and agree to these terms. You may not attempt to
re-identify the patients from whom these data were derived. Commercial entities should
contact the corresponding author.
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---
# QUEST-data
Paired H&E / multiplex immunofluorescence evaluation regions for
[QUEST](https://github.com/YAndrewL/QUEST).
## Stain cohorts
Each file is one region. The panel is per-region: `K` varies between files and the
channel order follows that file's own `biomarkers`, so index by marker name, never
by position.
| key | | |
|---|---|---|
| `he` | `(n, 224, 224, 3)` uint8 | H&E patches of that region |
| `mif` | `(n, 224, 224, K)` float16 | measured multiplex, same patches |
| `biomarkers` | `(K,)` str | that region's own panel |
| cohort | regions | patches | K | size |
|---|---|---|---|---|
| `crc_stain` | 100 | 12,154 | 50-54 | 17 GB |
| `breast_stain` | 100 | 10,789 | 53-54 | 13 GB |
| `lung_stain` | 100 | 20,585 | 36-54 | 23 GB |
| `melanoma_stain` | 77 | 6,768 | 45-54 | 9.4 GB |
## Mixed_10K
10,000 patches in 10 shards of 1,000, on one fixed 52-marker panel with the channel
axis second. `gt_mask` marks which channels were measured for each patch;
unmeasured channels are zero-filled and cannot be told from a true negative without
it.
| key | | |
|---|---|---|
| `he` | `(n, 224, 224, 3)` uint8 | |
| `mif` | `(n, 52, 224, 224)` float16 | |
| `biomarkers` | `(52,)` str | fixed panel |
| `gt_mask` | `(n, 52)` bool | measured channels |
```python
from huggingface_hub import snapshot_download
snapshot_download("yandrewl/QUEST-data", repo_type="dataset",
allow_patterns="crc_stain/*", local_dir="data")
```