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metadata
library_name: EMber
tags:
  - cryo-em
  - image-feature-extraction
  - model_hub_mixin
  - pytorch_model_hub_mixin

EMber: Learning the Shared Latent Structure of Cryo-EM Inverse Problems

Nithin Chalapathi 路 Theo Sternlieb 路 Ethan Han 路 Sonya M. Hanson 路 Pilar Cossio 路 Aditi S. Krishnapriyan 路 Ritwik Gupta

EMber is a family of pretrained vision transformers for extracting representations from single-particle cryo-EM particle images. Given a particle image, EMber produces an image-level embedding and spatial patch features for use in downstream analysis. The models were trained using self-distillation on over 50 million experimental particle images from 214 EMPIAR datasets, together with simulated projections from 268,000 molecular assemblies.

Check out our preprint here and code here.

EMber-Base has 85.3M parameters and uses a 16x16 patch size.