πŸ•ŠοΈ PocketGull RxGuard PGx (Pharmacogenomic Safety Sentinel)

Specialized clinical decision-support adapter evaluating patient metabolic phenotypes (CYP2D6, CYP2C19, CYP3A4, HLA-B) to prevent adverse drug events and toxic gene-drug interactions across humanitarian and inpatient settings.

🧬 Key Guardrails

  • CYP2D6 Poor/Ultra-Rapid Metabolizer Rules: Flags codeine, tramadol, and tamoxifen toxicity risks.
  • CYP2C19 Loss-of-Function Warnings: Intercepts clopidogrel (Plavix) hypo-responsiveness in post-PCI coronary care.
  • HLA-B*5701 Screening Gate: Enforces mandatory screening before abacavir dispensing to avert fatal hypersensitivity.
  • Cross-Border 6-Language Passport Integration: Generates multilingual PGx contraindication summaries in English, Spanish, French, Arabic, Ukrainian, and Swahili.
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