ποΈ PocketGull RxGuard PGx (Pharmacogenomic Safety Sentinel)
Specialized clinical decision-support adapter evaluating patient metabolic phenotypes (CYP2D6, CYP2C19, CYP3A4, HLA-B) to prevent adverse drug events and toxic gene-drug interactions across humanitarian and inpatient settings.
𧬠Key Guardrails
- CYP2D6 Poor/Ultra-Rapid Metabolizer Rules: Flags codeine, tramadol, and tamoxifen toxicity risks.
- CYP2C19 Loss-of-Function Warnings: Intercepts clopidogrel (Plavix) hypo-responsiveness in post-PCI coronary care.
- HLA-B*5701 Screening Gate: Enforces mandatory screening before abacavir dispensing to avert fatal hypersensitivity.
- Cross-Border 6-Language Passport Integration: Generates multilingual PGx contraindication summaries in English, Spanish, French, Arabic, Ukrainian, and Swahili.
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