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| license: mit | |
| library_name: pyaging | |
| tags: | |
| - pyaging | |
| - aging-clock | |
| - biology | |
| - transcriptomics | |
| # bitage | |
| Binarized whole-organism C. elegans RNA-seq clock that estimates temporally rescaled biological age; the released linear predictor sums coefficients for genes binarized on plus a 103.55-hour intercept. | |
| | | | | |
| |---|---| | |
| | **Predicts** | biological age | | |
| | **Species** | Caenorhabditis elegans | | |
| | **Tissue** | whole organism | | |
| | **Data type** | transcriptomics | | |
| | **Model type** | elastic net regression | | |
| | **Year** | 2021 | | |
| ## Use with pyaging | |
| ```python | |
| import pyaging as pya | |
| pya.pred.predict_age(adata, ["bitage"]) | |
| ``` | |
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). | |
| ## Citation | |
| Meyer, David H., and Björn Schumacher. "BiT age: A transcriptome-based aging clock near the theoretical limit of accuracy." Aging Cell 20 (2021): e13320. | |
| https://doi.org/10.1111/acel.13320 | |