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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

bohlin

Official minimum-lambda variant of the Bohlin gestational-age LASSO: pyaging implements the 251-CpG lambda.min model and converts its day-scale output to weeks. The paper/package default one-standard-error variant uses 96 CpGs and has nearly identical predictive performance.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts gestational age
Species Homo sapiens
Tissue cord blood
Data type DNA methylation
Model type LASSO regression
Year 2016

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["bohlin"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Bohlin, J., Håberg, S. E., Magnus, P. et al. Prediction of gestational age based on genome-wide differentially methylated regions. Genome Biology 17, 207 (2016).

https://doi.org/10.1186/s13059-016-1063-4