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| license: mit | |
| library_name: pyaging | |
| tags: | |
| - pyaging | |
| - aging-clock | |
| - biology | |
| - dna-methylation | |
| # compil6 | |
| Thirty-five-CpG whole-blood proxy score for persistent IL-6-related inflammatory burden, fitted against covariate-adjusted normalized plasma IL-6. | |
| | | | | |
| |---|---| | |
| | **Predicts** | interleukin-6 | | |
| | **Species** | Homo sapiens | | |
| | **Tissue** | whole blood | | |
| | **Data type** | DNA methylation | | |
| | **Model type** | elastic net regression | | |
| | **Year** | 2021 | | |
| ## Use with pyaging | |
| ```python | |
| import pyaging as pya | |
| pya.pred.predict_age(adata, ["compil6"]) | |
| ``` | |
| Browse every clock in the [pyaging Clock Catalogue](https://pyaging.readthedocs.io). | |
| ## Citation | |
| Stevenson, A. J., et al. “Creating and Validating a DNA Methylation-Based Proxy for Interleukin-6.” The Journals of Gerontology: Series A 76(12): 2284–2292 (2021). | |
| https://doi.org/10.1093/gerona/glab046 | |