metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
cvdwesterman
Whole-blood DNA-methylation score for cardiovascular risk. The paper's final cross-study learner stacks cohort-specific elastic-net Cox models; the packaged pyaging implementation is a 235-CpG linear score followed by a sigmoid.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | cardiovascular disease risk |
| Species | Homo sapiens |
| Tissue | whole blood |
| Data type | DNA methylation |
| Model type | elastic net Cox ensemble |
| Year | 2020 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["cvdwesterman"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Westerman, K. et al. Epigenomic assessment of cardiovascular disease risk and interactions with traditional risk metrics. Journal of the American Heart Association 9, e015299 (2020).