| { | |
| "approved_by_author": "\u231b", | |
| "citation": "Li, X. et al. Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults. Nature Communications 13, 5269 (2022).", | |
| "citations": 24, | |
| "citations_date": "2026-10-02", | |
| "clock_name": "dnamfili", | |
| "data_type": "DNA methylation", | |
| "doi": "https://doi.org/10.1038/s41467-022-32893-x", | |
| "journal": "Nature Communications", | |
| "last_author": "Hermann Brenner", | |
| "model_type": "LASSO regression", | |
| "n_features": 20, | |
| "notes": "Epigenetic frailty risk score (eFRS), a weighted 20-CpG whole-blood DNA-methylation score selected by LASSO from replicated frailty-associated loci.", | |
| "platform": [ | |
| "Illumina EPIC", | |
| "Illumina 450K" | |
| ], | |
| "population": "older adults", | |
| "predicts": [ | |
| "frailty risk" | |
| ], | |
| "research_only": null, | |
| "species": "Homo sapiens", | |
| "tissue": [ | |
| "whole blood" | |
| ], | |
| "training_target": [ | |
| "frailty" | |
| ], | |
| "unit": [ | |
| "unitless" | |
| ], | |
| "version": "0.5.7", | |
| "year": 2022 | |
| } |