| { |
| "approved_by_author": "\u231b", |
| "citation": "Fuentealba, M., Rouch, L., Guyonnet, S. et al. A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors. Nature Aging 5, 1207\u20131216 (2025).", |
| "citations": 45, |
| "citations_date": "2026-10-02", |
| "clock_name": "dnamic", |
| "data_type": "DNA methylation", |
| "doi": "https://doi.org/10.1038/s43587-025-00883-5", |
| "journal": "Nature Aging", |
| "last_author": "David Furman", |
| "model_type": "elastic net regression", |
| "n_features": 91, |
| "notes": "Whole-blood DNA-methylation predictor of intrinsic capacity, an average score across cognition, locomotion, psychological, sensory, and vitality domains; trained with tenfold cross-validated elastic net on INSPIRE-T and returning higher values for better capacity.", |
| "platform": [ |
| "Illumina EPIC" |
| ], |
| "population": "older adults", |
| "predicts": [ |
| "intrinsic capacity" |
| ], |
| "research_only": null, |
| "species": "Homo sapiens", |
| "tissue": [ |
| "whole blood" |
| ], |
| "training_target": [ |
| "intrinsic capacity" |
| ], |
| "unit": [ |
| "unitless" |
| ], |
| "version": "0.5.7", |
| "year": 2025 |
| } |
