ensembleagestatic / README.md
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metadata
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

ensembleagestatic

Single elastic-net static predictor of the median EnsembleAge.Dynamic calibrated age, trained on perturbed MethylGauge mice.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.

Predicts intervention-responsive epigenetic age
Species Mus musculus
Tissue multi-tissue
Data type DNA methylation
Model type elastic net regression
Year 2025

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["ensembleagestatic"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Haghani, A. et al. EnsembleAge: enhancing epigenetic age assessment with a multi-clock framework. GeroScience 48, 2873-2886 (2025).

https://doi.org/10.1007/s11357-025-01808-1