metadata
library_name: pyaging
tags:
- pyaging
- aging-clock
- biology
- dna-methylation
epicmithypo
Hypomethylation component of epiCMIT: a 1,164-CpG score ranging from 0 to 1 that tracks low-to-high relative proliferative history in normal and neoplastic B cells.
Model weights retain the original authors' terms; the pyaging software license does not relicense them.
| Predicts | mitotic age |
| Species | Homo sapiens |
| Tissue | B cells |
| Data type | DNA methylation |
| Model type | complement of mean methylation |
| Year | 2020 |
Use with pyaging
import pyaging as pya
pya.pred.predict_age(adata, ["epicmithypo"])
Browse every clock in the pyaging Clock Catalogue.
Citation
Duran-Ferrer, M., et al. "The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome." Nature Cancer 1 (2020): 1066-1081.